The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States von Beecham, AH, Amezcua, L, Chinea, A, Manrique, CP, Rubi, C, Isobe, N, Lund, BT, Santaniello, A, Beecham, GW, Burchard, EG, Comabella, M, Patsopoulos, N, Fitzgerald, K, Calabresi, PA, De Jager, P, Conti, DV, Delgado, SR, Oksenberg, JR, McCauley, JL

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Genome-wide scan demonstrates significant linkage for male sexual orientation von Sanders, A. R., Martin, E. R., Beecham, G. W., Guo, S., Dawood, K., Rieger, G., Badner, J. A., Gershon, E. S., Krishnappa, R. S., Kolundzija, A. B., Duan, J., Gejman, P. V., Bailey, J. M.

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Targeted sequencing of ABCA7 identifies splicing, stop-gain and intronic risk variants for Alzheimer disease von Kunkle, B.W., Carney, R.M., Kohli, M.A., Naj, A.C., Hamilton-Nelson, K.L., Whitehead, P.L., Wang, L., Lang, R., Cuccaro, M.L., Vance, J.M., Byrd, G.S., Beecham, G.W., Gilbert, J.R., Martin, E.R., Haines, J.L., Pericak-Vance, M.A.

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Utility of blood pressure genetic risk score in admixed Hispanic samples von Beecham, A H, Wang, L, Vasudeva, N, Liu, Z, Dong, C, Goldschmidt-Clermont, P J, Pericak-Vance, M A, Rundek, T, Seo, D, Blanton, S H, Sacco, R L, Beecham, G W

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Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population von Marca-Ysabel, Maria Victoria, Rajabli, Farid, Cornejo-Olivas, Mario, Whitehead, Patrice G., Hofmann, Natalia K., Illanes Manrique, Maryenela Zaida, Veliz Otani, Diego Martin, Milla Neyra, Ana Karina, Castro Suarez, Sheila, Meza Vega, Maria, Adams, Larry D., Mena, Pedro R., Rosario, Isasi, Cuccaro, Michael L., Vance, Jeffery M., Beecham, Gary W., Custodio, Nilton, Montesinos, Rosa, Mazzetti Soler, Pilar E., Pericak-Vance, Margaret A.

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Response to Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior" von Ganna, Andrea, Verweij, Karin J. H., Nivard, Michel G., Maier, Robert, Wedow, Robbee, Busch, Alexander S., Abdellaoui, Abdel, Guo, Shengru, Sathirapongsasuti, J. Fah, Lichtenstein, Paul, Lundstrom, Sebastian, Langstrom, Niklas, Auton, Adam, Harris, Kathleen Mullan, Beecham, Gary W., Martin, Eden R., Sanders, Alan R., Perry, John R. B., Neale, Benjamin M., Zietsch, Brendan P.

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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Abeta, tau, immunity and lipid processing von Kunkle, B. W., Grenier-Boley, B., Sims, R., Bis, J. C., Damotte, V., Naj, A. C., Boland, A., Vronskaya, M., van Der Lee, S. J., Amlie-Wolf, A., Bellenguez, C., Frizatti, A., Chouraki, V., Martin, E. R., Sleegers, K., Badarinarayan, N., Jakobsdottir, J., Hamilton-Nelson, K. L., Moreno-Grau, S., Olaso, R., Raybould, R., Chen, Y., Kuzma, A. B., Hiltunen, M., Morgan, T., Ahmad, S., Vardarajan, B. N., Epelbaum, J., Hoffmann, P., Boada, M., Beecham, G. W., Garnier, J. G., Harold, D., Fitzpatrick, A. L., Valladares, O., Moutet, M. L., Gerrish, A., Qu, L., Bacq, D., Denning, N., Jian, X., Zhao, Y., del Zompo, M., Fox, N. C., Choi, S. H., Mateo, I., Hughes, J. T., Adams, H. H., Malamon, J., Sanchez-Garcia, F., Patel, Y., Brody, J. A., Dombroski, B. A., Naranjo, M. C. D., Daniilidou, M., Eiriksdottir, G., Mukherjee, S., Wallon, D., Uphill, J., Aspelund, T., Cantwell, L. B., Garzia, F., Galimberti, D., Hofer, E., Butkiewicz, M., Fin, B., Scarpini, E., Sarnowski, C., Bush, W. S., Meslage, S., Kornhuber, J., White, C. C., Song, Y., Barber, R. C., Engelborghs, S., Sordon, S., Voijnovic, D., Adams, P. M., Vandenberghe, R., Mayhaus, M., Cupples, L. A., Albert, M. S., de Deyn, P. P., Gu, W., Himali, J. J., Beekly, D., Squassina, A., Hartmann, A. M., Orellana, A., Blacker, D., Rodriguez-Rodriguez, E., Lovestone, S., Garcia, M. E., Doody, R. S., Munoz-Fernadez, C., Sussams, R., Lin, H., Fairchild, T. J., Benito, Y. A., Holmes, C.

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Genome studies must account for history-Response von Ganna, Andrea, Verweij, Karin J H, Nivard, Michel G, Maier, Robert, Wedow, Robbee, Busch, Alexander S, Abdellaoui, Abdel, Guo, Shengru, Sathirapongsasuti, J Fah, Lichtenstein, Paul, Lundström, Sebastian, Långström, Niklas, Auton, Adam, Harris, Kathleen Mullan, Beecham, Gary W, Martin, Eden R, Sanders, Alan R, Perry, John R B, Neale, Benjamin M, Zietsch, Brendan P

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Genomic evidence consistent with antagonistic pleiotropy may help explain the evolutionary maintenance of same-sex sexual behaviour in humans von Zietsch, Brendan P., Sidari, Morgan J., Abdellaoui, Abdel, Maier, Robert, Långström, Niklas, Guo, Shengru, Beecham, Gary W., Martin, Eden R., Sanders, Alan R., Verweij, Karin J. H.

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Author Correction: Genomic evidence consistent with antagonistic pleiotropy may help explain the evolutionary maintenance of same-sex sexual behaviour in humans von Zietsch, Brendan P., Sidari, Morgan J., Abdellaoui, Abdel, Maier, Robert, Långström, Niklas, Guo, Shengru, Beecham, Gary W., Martin, Eden R., Sanders, Alan R., Verweij, Karin J. H.

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Genomic evidence consistent with antagonistic pleiotropy may help explain the evolutionary maintenance of same-sex sexual behaviour in humans (Aug, 10.1038/s41562-021-01168-8, 2021... von Zietsch, Brendan P., Sidari, Morgan J., Abdellaoui, Abdel, Maier, Robert, Langstrom, Niklas, Guo, Shengru, Beecham, Gary W., Martin, Eden R., Sanders, Alan R., Verweij, Karin J. H.

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Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease von Jakobsdottir, J., Raybould, R., Vronskaya, M., White, C.C., Herms, S., Smith, A.V., Funk, C.C., Sánchez-Juan, P., Wolters, F.J., Zhao, Y., Malamon, J., Dombroski, B., Whitehead, P., Cantwell, L.B., Burgess, J.D., Adams, H.H., Chakrabarty, P., Beiser, A.S., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Henández, I., Tarraga, L., Albert, M.S., Emilsson, V., Doody, R.S., Spalletta, G., Frosch, M.P., Kamboh, M.I., Marshall, R., Fairén, M.D., Uphill, J., Hughes, J.T., Orfei, M.D., Ciaramella, A., Mayhaus, M., Brookes, K., Cupidi, C., Gill, M., Apostolova, L.G., Asthana, S., Boeve, B.F., Burke, J.R., Buxbaum, J.D., Cairns, N.J., Chui, H.C., Gearing, M., Harrell, L.E., Jarvik, G.P., Leverenz, J.B., Li, G., Lieberman, A.P., McCormick, W.C., Miller, C.A., Pankratz, V.S., Raskind, M., Tanzi, R.E., Troncoso, J.C., Wingo, T.S., Garzia, F., Vandenberghe, R., Fernadez, C.M., Lilius, L., Koivisto, A.M., Dermecourt, V., Fievet, N., Brice, A., Ritchie, K., Dubois, B., Himali, J.J., Tschanz, J., Fitzpatrick, A.L., Kukull, W.A., Larson, E.B., Rotter, J.I., Coto, E., Gallo, M., Galimberti, D., Tsuang, D.W., Daniele, A., Nacmias, B., Rubinsztein, D.C., Bras, J., Collinge, J., Tsolaki, M., Uitterlinden, A.G., Powell, J., Golde, T.E., De Jager, P.L., Ertekin-Taner, N., Passmore, P., Younkin, S.G., Ortega-Cubero, S., Jones, L., Mayeux, R., Amin, N., Holmans, P.A., Pericak-Vance, M.A., Lambert, J.C., Destefano, Anita L.

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CALHM1 Polymorphism is not Associated with Late‐onset Alzheimer Disease von Beecham, Gary W., Schnetz‐Boutaud, Nathalie, Haines, Jonathan L., Pericak‐Vance, Margaret A.

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Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease von Lai, D, Alipanahi, B, Fontanillas, P, Schwantes-An, TH, Aasly, J, Alcalay, RN, Beecham, GW, Berg, D, Bressman, S, Brice, A, Brockman, K, Clark, L, Cookson, M, Das, S, Van Deerlin, V, Follett, J, Farrer, MJ, Trinh, J, Gasser, T, Goldwurm, S, Gustavsson, E, Klein, C, Lang, AE, Langston, JW, Latourelle, J, Lynch, T, Marder, K, Marras, C, Martin, ER, McLean, CY, Mejia-Santana, H, Molho, E, Myers, RH, Nuytemans, K, Ozelius, L, Payami, H, Raymond, D, Rogaeva, E, Rogers, MP, Ross, OA, Samii, A, Saunders-Pullman, R, Schüle, B, Schulte, C, Scott, WK, Tanner, C, Tolosa, E, Tomkins, JE, Vilas, D, Trojanowski, JQ, Uitti, R, Vance, JM, Visanji, NP, Wszolek, ZK, Zabetian, CP, Mirelman, A, Giladi, N, Orr Urtreger, A, Cannon, P, Fiske, B, Foroud, T, Agee, M, Auton, A, Bell, RK, Bryc, K, Elson, SL, Furlotte, NA, Hinds, DA, Huber, KE, Kleinman, A, Litterman, NK, McIntyre, MH, Mountain, JL, Noblin, ES, Northover, CAM, Pitts, SJ, Fah Sathirapongsasuti, J, Sazonova, OV, Shelton, JF, Shringarpure, S, Tian, C, Tung, JY, Vacic, V, Wilson, CH

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Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study von Reiman, EM, Arboleda-Velasquez, JF, Quiroz, YT, Huentelman, MJ, Beach, TG, Caselli, RJ, Chen, Y, Su, Y, Myers, AJ, Hardy, J, Paul Vonsattel, J, Younkin, SG, Bennett, DA, De Jager, PL, Larson, EB, Crane, PK, Keene, CD, Kamboh, MI, Kofler, JK, Duque, L, Gilbert, JR, Gwirtsman, HE, Buxbaum, JD, Dickson, DW, Frosch, MP, Ghetti, BF, Lunetta, KL, Wang, L-S, Hyman, BT, Kukull, WA, Foroud, T, Haines, JL, Mayeux, RP, Pericak-Vance, MA, Schneider, JA, Trojanowski, JQ, Farrer, LA, Schellenberg, GD, Beecham, GW, Montine, TJ, Jun, GR, Alzheimer’s Disease Genetics Consortium

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Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting von Chauhan, G, Adams, HHH, Satizabal, CL, Bis, JC, Teumer, A, Sargurupremraj, M, Hofer, E, Trompet, S, Hilal, S, Smith, AV, Jian, X, Malik, R, Traylor, M, Pulit, SL, Amouyel, P, Mazoyer, B, Zhu, YC, Kaffashian, S, Beecham, GW, Montine, TJ, Schellenberg, GD, Kjartansson, O, Guðnason, V, Knopman, DS, Griswold, ME, Windham, BG, Gottesman, RF, Mosley, TH, Schmidt, R, Saba, Y, Schmidt, H, Takeuchi, F, Nabika, T, Kato, N, Rajan, KB, Aggarwal, NT, De Jager, PL, Evans, DA, Psaty, BM, Rotter, JI, Rice, K, Lopez, OL, Liao, J, Chen, C, Cheng, CY, Wong, TY, Ikram, MK, van der Lee, SJ, Amin, N, Chouraki, V, Destefano, AL, Aparicio, HJ, Romero, JR, Maillard, P, Decarli, C, Wardlaw, JM, Del C. Valdés Hernández, M, Luciano, M, Liewald, D, Deary, IJ, Starr, JM, Bastin, ME, Maniega, SM, Slagboom, PE, Beekman, M, Deelen, J, Uh, HW, Lemmens, R, Brodaty, H, Wright, MJ, Ames, D, Boncoraglio, GB, Hopewell, JC, Beecham, AH, Blanton, SH, Wright, CB, Sacco, RL, Wen, W, Thalamuthu, A, Armstrong, NJ, Chong, E, Schofield, PR, Kwok, JB, van der Grond, J, Stott, DJ, Ford, I, Jukema, JW, Vernooij, MW, Hofman, A, Uitterlinden, AG, van der Lugt, A, Wittfeld, K, Grabe, HJ, Hosten, N, von Sarnowski, B, Völker, U, Levi, C, Jimenez-Conde, J, Sachdev, Perminder, Mather, Karen

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A statistical framework for cross-tissue transcriptome-wide association analysis von Li, M, Lu, Q, Wang, J, Zekavat, SM, Yu, Z, Gu, J, Mukherjee, S, Natarajan, P, Kuzma, A, Crane, PK, Lu, H, Zhao, H, Albert, MS, Arnold, SE, Asthana, S, Beach, TG, Beekly, D, Bigio, EH, Bowen, JD, Boxer, A, Burke, JR, Cairns, NJ, Cantwell, LB, Cao, C, Carlson, CS, Carney, RM, Chui, HC, Cribbs, DH, Crocco, EA, De Jager, PL, DeCarli, C, Dick, M, Doody, RS, Faber, KM, Fallon, KB, Farlow, MR, Farrer, LA, Ferris, S, Frosch, MP, Gearing, M, Geschwind, DH, Goate, AM, Graff-Radford, NR, Green, RC, Growdon, JH, Haines, JL, Hardy, J, Huentelman, MJ, Hyman, BT, Jun, G, Kamboh, MI, Karydas, A, Kauwe, JSK, Kaye, JA, Kim, R, Kowall, NW, Kukull, WA, Martiniuk, F, Mash, DC, McCurry, SM, Mesulam, M, Miller, BL, Miller, CA, Miller, JW, Montine, TJ, Morris, JC, Naj, AC, O'Bryant, S, Olichney, JM, Parisi, JE, Paulson, HL, Pericak-Vance, MA, Peskind, E, Pierce, A, Potter, H, Reiman, EM, Reisberg, B, Reisch, JS, Ringman, JM, Roberson, ED, Rogaeva, E, Saykin, AJ, Schellenberg, GD, Schneider, JA, Schneider, LS, Sonnen, JA, Spina, S, Trojanowski, JQ, Troncoso, JC, Van Eldik, LJ, Vinters, HV, Weintraub, S, Welsh-Bohmer, KA, Wilhelmsen, KC, Williamson, J, Wingo, TS, Wright, CB, Younkin, SG, Yu, C-E, Yu, L

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Transethnic genome-wide scan identifies novel Alzheimer's disease loci von Jun, GR, Chung, J, Mez, J, Barber, R, Beecham, GW, Bennett, DA, Buxbaum, JD, Byrd, GS, Carrasquillo, MM, Crane, PK, Cruchaga, C, De Jager, P, Ertekin-Taner, N, Evans, D, Fallin, MD, Foroud, TM, Friedland, RP, Goate, AM, Graff-Radford, NR, Hendrie, H, Hall, KS, Hamilton-Nelson, KL, Inzelberg, R, Kamboh, MI, Kauwe, JSK, Kukull, WA, Kunkle, BW, Kuwano, R, Larson, EB, Logue, MW, Manly, JJ, Martin, ER, Montine, TJ, Mukherjee, S, Naj, A, Reiman, EM, Reitz, C, Sherva, R, St George-Hyslop, PH, Thornton, T, Younkin, SG, Vardarajan, BN, Wang, L-S, Wendlund, JR, Winslow, AR, Haines, J, Mayeux, R, Pericak-Vance, MA, Schellenberg, G, Lunetta, KL, Farrer, LA

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Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease von Peloso, GM, van der Lee, SJ, Sims, R, Naj, AC, Bellenguez, C, Badarinarayan, N, Jakobsdottir, J, Kunkle, BW, Boland, A, Raybould, R, Bis, JC, Martin, ER, Grenier-Boley, B, Heilmann-Heimbach, S, Chouraki, V, Kuzma, AB, Sleegers, K, Vronskaya, M, Ruiz, A, Graham, RR, Olaso, R, Hoffmann, P, Grove, ML, Vardarajan, BN, Hiltunen, M, Nöthen, MM, White, CC, Hamilton-Nelson, KL, Epelbaum, J, Maier, W, Choi, SH, Beecham, GW, Dulary, C, Herms, S, Smith, AV, Funk, CC, Derbois, Forstner, AJ, Ahmad, S, Li, H, Bacq, D, Harold, D, Satizabal, CL, Valladares, O, Squassina, A, Thomas, R, Brody, JA, Qu, L, Sánchez-Juan, P, Morgan, T, Wolters, FJ, Zhao, Y, Garcia, FS, Denning, N, Fornage, M, Malamon, J, Naranjo, MCD, Majounie, E, Mosley, TH, Dombroski, B, Wallon, D, Lupton, MK, Dupuis, J, Whitehead, P, Fratiglioni, L, Medway, C, Jian, X, Mukherjee, S, Keller, L, Brown, K, Lin, H, Cantwell, LB, Panza, F, McGuinness, B, Moreno-Grau, S, Burgess, JD, Solfrizzi, V, Proitsi, P, Adams, HH, Allen, M, Seripa, D, Pastor, P, Cupples, LA, Price, ND, Hannequin, D, Frank-García, A, Levy, D, Chakrabarty, P, Caffarra, P, Giegling, I, Beiser, AS, Giedraitis, V, Hampel, H, Garcia, ME, Wang, X, Lannfelt, L, Mecocci, P, Eiriksdottir, G, Crane, PK

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A novel Alzheimer disease locus located near the gene encoding tau protein von Jun, G, Ibrahim-Verbaas, CA, Vronskaya, M, Lambert, J-C, Chung, J, Naj, AC, Kunkle, BW, Wang, L-S, Bis, JC, Bellenguez, C, Harold, D, Lunetta, KL, Destefano, AL, Grenier-Boley, B, Sims, R, Beecham, GW, Smith, AV, Hamilton-Nelson, KL, Ikram, MA, Fievet, N, Denning, N, Martin, ER, Schmidt, H, Dunstan, ML, Valladares, O, Laza, AR, Zelenika, D, Ramirez, A, Foroud, TM, Choi, S-H, Boland, A, Kukull, WA, Pasquier, F, Beekly, D, Fitzpatrick, AL, Hanon, O, Barber, R, Gudnason, V, Campion, D, Love, S, Bennett, DA, Amin, N, Buxbaum, JD, Lopez, OL, Deramecourt, V, Fox, NC, Cantwell, LB, Tárraga, L, Dufouil, C, Hardy, J, Crane, PK, Eiriksdottir, G, Hannequin, D, Clarke, R, Mosley, TH, Brayne, C, Maier, W, De Jager, P, Emilsson, V, Dartigues, J-F, Hampel, H, Kamboh, MI, de Bruijn, RFAG, Tzourio, C, Pastor, P, Larson, EB, Rotter, JI, O'Donovan, MC, Montine, TJ, Nalls, MA, Mead, S, Reiman, EM, Jonsson, PV, Holmes, C, St George-Hyslop, PH, Boada, M, Passmore, P, Wendland, JR, Schmidt, R, Morgan, K, Powell, JF, Younkin, SG, Jakobsdóttir, J, Kauwe, JSK, Wilhelmsen, KC, Rujescu, D, Hofman, A, Jones, L, IGAP Consortium, Van Broeckhoven, C, Launer, LJ, Mayeux, R, Lathrop, M, Goate, AM, Escott-Price, V, Amouyel, P, Williams, J, van Duijn, CM, Schellenberg, GD, Farrer, LA

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