Protein-Based Adjuvants for Vaccines as Immunomodulators of the Innate and Adaptive Immune Response: Current Knowledge, Challenges, and Future Opportunities von Díaz-Dinamarca, Diego A, Salazar, Michelle L, Castillo, Byron N, Manubens, Augusto, Vasquez, Abel E, Salazar, Fabián, Becker, María Inés

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Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer von Lladser, Alvaro, Manubens, Augusto, Becker, María Inés, Ferreira, Jorge, Jara, Lilian, Venuti, Aldo, Curzio, Gianfranca, Paolini, Francesca, Villar, Javiera, Del Campo, Miguel, Mora Román, Juan José, Murgas, Paola

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Immunopurification of Golgi vesicles by magnetic sorting von Mura, Casilda V, Becker, Marı́a Inés, Orellana, Ariel, Wolff, Daniel

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A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata promotes potent anti-tumor activity in melanoma von Arancibia, Sergio, Espinoza, Cecilia, Salazar, Fabián, Del Campo, Miguel, Tampe, Ricardo, Zhong, Ta-Ying, De Ioannes, Pablo, Moltedo, Bruno, Ferreira, Jorge, Lavelle, Ed C, Manubens, Augusto, De Ioannes, Alfredo E, Becker, María Inés

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Surface immunogenic protein from Streptococcus agalactiae and Fissurella latimarginata hemocyanin are TLR4 ligands and activate MyD88- and TRIF dependent signaling pathways von Díaz-Dinamarca, Diego A., Salazar, Michelle L., Escobar, Daniel F., Castillo, Byron N., Valdebenito, Bastián, Díaz, Pablo, Manubens, Augusto, Salazar, Fabián, Troncoso, Mayarling F., Lavandero, Sergio, Díaz, Janepsy, Becker, María Inés, Vásquez, Abel E.

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A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells inhibiting tumor growth von Gleisner, María Alejandra, Pereda, Cristián, Tittarelli, Andrés, Navarrete, Mariela, Fuentes, Camila, Ávalos, Ignacio, Tempio, Fabian, Araya, Juan Pablo, Becker, María Inés, González, Fermín Eduardo, López, Mercedes Natalia, Salazar-Onfray, Flavio

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Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non‐specific immunostimulatory effects von Arancibia, Sergio, Campo, Miguel Del, Nova, Esteban, Salazar, Fabián, Becker, María Inés

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TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals von Jiménez, José M, Salazar, Michelle L, Arancibia, Sergio, Villar, Javiera, Salazar, Fabián, Brown, Gordon D, Lavelle, Ed C, Martínez-Pomares, Luisa, Ortiz-Quintero, Jafet, Lavandero, Sergio, Manubens, Augusto, Becker, María Inés

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N-Glycosylation of mollusk hemocyanins contributes to their structural stability and immunomodulatory properties in mammals von Salazar, Michelle L., Jimènez, Josè M., Villar, Javiera, Rivera, Maira, Báez, Mauricio, Manubens, Augusto, Becker, María Inès

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Antiproliferative and Uncoupling Effects of Delocalized, Lipophilic, Cationic Gallic Acid Derivatives on Cancer Cell Lines. Validation in Vivo in Singenic Mice von Jara, José A, Castro-Castillo, Vicente, Saavedra-Olavarría, Jorge, Peredo, Liliana, Pavanni, Mario, Jaña, Fabián, Letelier, María Eugenia, Parra, Eduardo, Becker, María Inés, Morello, Antonio, Kemmerling, Ulrike, Maya, Juan Diego, Ferreira, Jorge

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Cutting Edge: Stealth Influenza Virus Replication Precedes the Initiation of Adaptive Immunity von Moltedo, Bruno, Lopez, Carolina B, Pazos, Michael, Becker, Maria Ines, Hermesh, Tamar, Moran, Thomas M

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Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1 von Pacheco, Rodrigo, Quezada, Sergio A, Kalergis, Alexis M, Becker, María Inés, Ferreira, Jorge, De Ioannes, Alfredo E

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Oxidative Modifications in Crystallin Proteins and Lens Epithelial Cells Associated with Photosensitized Reactions Mediated by the Major Chromophore Arising from Glucose Degradatio... von Vargas, Francisco, Becker, María Inés, Friguet, Bertrand, Silva, Eduardo, Ávila, Felipe

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Immunocompetence of breeding females is sensitive to cortisol levels but not to communal rearing in the degu ( Octodon degus ) von Ebensperger, Luis A, León, Cecilia, Ramírez-Estrada, Juan, Abades, Sebastian, Hayes, Loren D, Nova, Esteban, Salazar, Fabián, Bhattacharjee, Joydeep, Becker, María Inés

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Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages von Zhong, Ta-Ying, Arancibia, Sergio, Born, Raimundo, Tampe, Ricardo, Villar, Javiera, Del Campo, Miguel, Manubens, Augusto, Becker, María Inés

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Structural insights into a functional unit from an immunogenic mollusk hemocyanin von Muñoz, Sebastián M., Vallejos-Baccelliere, Gabriel, Manubens, Augusto, Salazar, Michelle L., Nascimento, Andrey F.Z., Tapia-Reyes, Patricio, Meneses, Claudio, Ambrosio, Andre L.B., Becker, María Inés, Guixé, Victoria, Castro-Fernandez, Victor

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Concholepas hemocyanin biosynthesis takes place in the hepatopancreas, with hemocytes being involved in its metabolism von Manubens, Augusto, Salazar, Fabián, Haussmann, Denise, Figueroa, Jaime, Del Campo, Miguel, Pinto, Jonathan Martínez, Huaquín, Laura, Venegas, Alejandro, Becker, María Inés

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Immunodominant role of CCHA subunit of Concholepas hemocyanin is associated with unique biochemical properties von Becker, María Inés, Fuentes, Alejandra, Del Campo, Miguel, Manubens, Augusto, Nova, Esteban, Oliva, Harold, Faunes, Fernando, Valenzuela, María Antonieta, Campos-Vallette, Marcelo, Aliaga, Alvaro, Ferreira, Jorge, De Ioannes, Alfredo E., De Ioannes, Pablo, Moltedo, Bruno

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C‐type lectin receptors MR and DC‐SIGN are involved in recognition of hemocyanins, shaping their immunostimulatory effects on human dendritic cells von Villar, Javiera, Salazar, Michelle L., Jiménez, José M., Campo, Miguel Del, Manubens, Augusto, Gleisner, María Alejandra, Ávalos, Ignacio, Salazar‐Onfray, Flavio, Salazar, Fabián, Mitchell, Daniel A, Alshahrani, Mohammad Y, Martínez‐Pomares, Luisa, Becker, María Inés

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The oxygen-binding properties of hemocyanin from the mollusk Concholepas concholepas von González, Andrea, Nova, Esteban, Del Campo, Miguel, Manubens, Augusto, De Ioannes, Alfredo, Ferreira, Jorge, Becker, María Inés

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