Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition von Soucheray, Margaret, Capelletti, Marzia, Pulido, Inés, Kuang, Yanan, Paweletz, Cloud P, Becker, Jeffrey H, Kikuchi, Eiki, Xu, Chunxiao, Patel, Tarun B, Al-Shahrour, Fatima, Carretero, Julián, Wong, Kwok-Kin, Jänne, Pasi A, Shapiro, Geoffrey I, Shimamura, Takeshi

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Chromium (VI) promotes lung cancer initiation by activating EGF/ALDH1A1 signalling von Metropulos, Anastasia E., Becker, Jeffrey H., Principe, Daniel R.

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Non-small cell lung carcinoma spheroid models in agarose microwells for drug response studies von Luan, Qiyue, Becker, Jeffrey H, Macaraniag, Celine, Massad, Malek G, Zhou, Jian, Shimamura, Takeshi, Papautsky, Ian

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CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC von Becker, Jeffrey H, Gao, Yandi, Soucheray, Margaret, Pulido, Ines, Kikuchi, Eiki, Rodríguez, María L, Gandhi, Rutu, Lafuente-Sanchis, Aranzazu, Aupí, Miguel, Alcácer Fernández-Coronado, Javier, Martín-Martorell, Paloma, Cremades, Antonio, Galbis-Caravajal, José M, Alcácer, Javier, Christensen, Camilla L, Simms, Patricia, Hess, Ashley, Asahina, Hajime, Kahle, Michael P, Al-Shahrour, Fatima, Borgia, Jeffrey A, Lahoz, Agustín, Insa, Amelia, Juan, Oscar, Jänne, Pasi A, Wong, Kwok-Kin, Carretero, Julian, Shimamura, Takeshi

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Endothelin-1-Mediated Drug Resistance in EGFR -Mutant Non-Small Cell Lung Carcinoma von Pulido, Inés, Ollosi, Stephen, Aparisi, Salvador, Becker, Jeffrey H, Aliena-Valero, Alicia, Benet, Marta, Rodríguez, María L, López, Adrián, Tamayo-Torres, Eva, Chuliá-Peris, Lourdes, García-Cañaveras, Juan Carlos, Soucheray, Margaret, Dalheim, Annika V, Salom, Juan B, Qiu, Wei, Kaja, Simon, Fernández-Coronado, Javier Alcácer, Alandes, Sandra, Alcácer, Javier, Al-Shahrour, Fátima, Borgia, Jeffrey A, Juan, Oscar, Nishimura, Michael I, Lahoz, Agustín, Carretero, Julián, Shimamura, Takeshi

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Endothelin-1-mediated Drug Resistance in EGFR-mutant NSCLC von Pulido, Inés, Ollosi, Stephen, Aparisi, Salvador, Becker, Jeffrey H., Aliena-Valero, Alicia, Benet, Marta, Rodríguez, María L., López, Adrián, Tamayo-Torres, Eva, Chuliá-Peris, Lourdes, García-Cañaveras, Juan Carlos, Soucheray, Margaret, Dalheim, Annika V., Salom, Juan B., Qiu, Wei, Kaja, Simon, Fernández-Coronado, Javier Alcácer, Alandes, Sandra, Alcácer, Javier, Al-Shahrour, Fátima, Borgia, Jeffrey A., Juan, Oscar, Nishimura, Michael I., Lahoz, Agustín, Carretero, Julián, Shimamura, Takeshi

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Abstract LB-085: A new role for LKB1 to regulate Heat Shock Protein 90 activity von Becker, Jeffrey H., Kahle, Michael P., Soucheray, Margaret, Pulido, Ines, Al-Shahrour, Fatima, Pino, Manuel Sanchez del, Wong, Kwok-Kin, Carretero, Julian, Shimamura, Takeshi

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Abstract LB-C21: CXCR7 expression is necessary for the maintenance of mesenchymal phenotype in acquired EGFR TKI resistance in NSCLC von Becker, Jeffrey H., Gao, Yandi, Pulido, Ines, Kikuchi, Eiki, Soucheray, Margaret, Gandhi, Rutu, Christensen, Camilla L., Al-shahrour, Fatima, Wong, Kwok-Kin, Carretero, Julian, Shimamura, Takeshi

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Abstract 766: Suppression of gefitinib-induced EMT in EGFR mutant NSCLC preferentially selects for acquired T790M von Soucheray, Margaret, Capelletti, Marzia, Pulido, Ines, Kuang, Yunan, Paweletz, Cloud P., Becker, Jeffrey H., Kikuchi, Eiki, Xu, Chunxiao, Patel, Tarun B., Al-shahrour, Fatima, Carretero, Julian, Wong, Kwok-Kin, Janne, Pasi A., Shapiro, Geoffrey I., Shimamura, Takeshi

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Assessment of multi-modality evaluations of obscure gastrointestinal bleeding von Law, Ryan, Varayil, Jithinraj E, WongKeeSong, Louis M, Fidler, Jeff, Fletcher, Joel G, Barlow, John, Alexander, Jeffrey, Rajan, Elizabeth, Hansel, Stephanie, Becker, Brenda, Larson, Joseph J, Enders, Felicity T, Bruining, David H, Coelho-Prabhu, Nayantara

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Fulminant Myocarditis with Combination Immune Checkpoint Blockade von Johnson, Douglas B, Balko, Justin M, Compton, Margaret L, Chalkias, Spyridon, Gorham, Joshua, Xu, Yaomin, Hicks, Mellissa, Puzanov, Igor, Alexander, Matthew R, Bloomer, Tyler L, Becker, Jason R, Slosky, David A, Phillips, Elizabeth J, Pilkinton, Mark A, Craig-Owens, Laura, Kola, Nina, Plautz, Gregory, Reshef, Daniel S, Deutsch, Jonathan S, Deering, Raquel P, Olenchock, Benjamin A, Lichtman, Andrew H, Roden, Dan M, Seidman, Christine E, Koralnik, Igor J, Seidman, Jonathan G, Hoffman, Robert D, Taube, Janis M, Diaz, Luis A, Anders, Robert A, Sosman, Jeffrey A, Moslehi, Javid J

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Annual Research Review: Perspectives on progress in ADHD science – from characterization to cause von Sonuga‐Barke, Edmund J.S., Becker, Stephen P., Bölte, Sven, Castellanos, Francisco Xavier, Franke, Barbara, Newcorn, Jeffrey H., Nigg, Joel T., Rohde, Luis Augusto, Simonoff, Emily

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Postnatal exposure to household disinfectants, infant gut microbiota and subsequent risk of overweight in children von Tun, Mon H., MBBS MSc, Kozyrskyj, Anita L., PhD, Tun, Hein M., DVM PhD, Mahoney, Justin J., MSc, Mandhane, Piush J., MD PhD, Konya, Theodore B., MSc, Brook, Jeffrey R., PhD, Lou, Wendy, PhD, Scott, James A., PhD, Guttman, David S., PhD, Becker, Allan B., MD, Turvey, Stuart E., MBBS DPhil, Subbarao, Padmaja, MD MSc, Sears, Malcolm R., MBChB, Takarao, Tim K., MD MSc

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Safe Cycling: How Do Risk Perceptions Compare With Observed Risk? von Winters, Meghan, Babul, Shelina, Becker, H. J. E. H. (Jack), Brubacher, Jeffrey R., Chipman, Mary, Cripton, Peter, Cusimano, Michael D., Friedman, Steven M., Harris, M. Anne, Hunte, Garth, Monro, Melody, Reynolds, Conor C. O., Shen, Hui, Teschke, Kay

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CD56bright NK cells exhibit potent antitumor responses following IL-15 priming von Wagner, Julia A, Rosario, Maximillian, Romee, Rizwan, Berrien-Elliott, Melissa M, Schneider, Stephanie E, Leong, Jeffrey W, Sullivan, Ryan P, Jewell, Brea A, Becker-Hapak, Michelle, Schappe, Timothy, Abdel-Latif, Sara, Ireland, Aaron R, Jaishankar, Devika, King, Justin A, Vij, Ravi, Clement, Dennis, Goodridge, Jodie, Malmberg, Karl-Johan, Wong, Hing C, Fehniger, Todd A

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Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1 von Garrelfs, Sander F, Frishberg, Yaacov, Hulton, Sally A, Koren, Michael J, O’Riordan, William D, Cochat, Pierre, Deschênes, Georges, Shasha-Lavsky, Hadas, Saland, Jeffrey M, van’t Hoff, William G, Fuster, Daniel G, Magen, Daniella, Moochhala, Shabbir H, Schalk, Gesa, Simkova, Eva, Groothoff, Jaap W, Sas, David J, Meliambro, Kristin A, Lu, Jiandong, Sweetser, Marianne T, Garg, Pushkal P, Vaishnaw, Akshay K, Gansner, John M, McGregor, Tracy L, Lieske, John C

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Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer von Povsic, Thomas J., MD, PhD, Lawrence, Monica G., MD, Lincoff, A. Michael, MD, Mehran, Roxana, MD, Rusconi, Christopher P., PhD, Zelenkofske, Steven L., DO, Huang, Zhen, MS, Sailstad, Jeffrey, BS, Armstrong, Paul W., MD, Steg, P. Gabriel, MD, Bode, Christoph, MD, Becker, Richard C., MD, Alexander, John H., MD, MHS, Adkinson, N. Franklin, MD, Levinson, Arnold I., MD

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Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis von Nissen, Steven E, Yeomans, Neville D, Solomon, Daniel H, Lüscher, Thomas F, Libby, Peter, Husni, M. Elaine, Graham, David Y, Borer, Jeffrey S, Wisniewski, Lisa M, Wolski, Katherine E, Wang, Qiuqing, Menon, Venu, Ruschitzka, Frank, Gaffney, Michael, Beckerman, Bruce, Berger, Manuela F, Bao, Weihang, Lincoff, A. Michael

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Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial von Orban, Tihamer, MD, Bundy, Brian, PhD, Becker, Dorothy J, Prof, DiMeglio, Linda A, MD, Gitelman, Stephen E, Prof, Goland, Robin, Prof, Gottlieb, Peter A, Prof, Greenbaum, Carla J, MD, Marks, Jennifer B, Prof, Monzavi, Roshanak, MD, Moran, Antoinette, Prof, Raskin, Philip, Prof, Rodriguez, Henry, Prof, Russell, William E, Prof, Schatz, Desmond, Prof, Wherrett, Diane, MD, Wilson, Darrell M, Prof, Krischer, Jeffrey P, Prof, Skyler, Jay S, Dr, Prof

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Approaches for describing and communicating overall uncertainty in toxicity characterizations: U.S. Environmental Protection Agency's Integrated Risk Information System (IRIS) as a... von Beck, Nancy B., Becker, Richard A., Erraguntla, Neeraja, Farland, William H., Grant, Roberta L., Gray, George, Kirman, Christopher, LaKind, Judy S., Jeffrey Lewis, R., Nance, Patricia, Pottenger, Lynn H., Santos, Susan L., Shirley, Stephanie, Simon, Ted, Dourson, Michael L.

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