A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas von Foulks, Jason M, Carpenter, Kent J, Luo, Bai, Xu, Yong, Senina, Anna, Nix, Rebecca, Chan, Ashley, Clifford, Adrianne, Wilkes, Marcus, Vollmer, David, Brenning, Benjamin, Merx, Shannon, Lai, Shuping, McCullar, Michael V, Ho, Koc-Kan, Albertson, Daniel J, Call, Lee T, Bearss, Jared J, Tripp, Sheryl, Liu, Ting, Stephens, Bret J, Mollard, Alexis, Warner, Steven L, Bearss, David J, Kanner, Steven B

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Design, Synthesis, and Biological Evaluation of a Series of Novel AXL Kinase Inhibitors von Mollard, Alexis, Warner, Steven L, Call, Lee T, Wade, Mark L, Bearss, Jared J, Verma, Anupam, Sharma, Sunil, Vankayalapati, Hariprasad, Bearss, David J

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Patterns and Significance of PIM Kinases in Urothelial Carcinoma von Albertson, Daniel J, Schmidt, Robert L, Bearss, Jared J, Tripp, Sheryl R, Bearss, David J, Liu, Ting

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Abstract C92: HCI-2577 inhibits LSD1 and modulates histone marks in Ewing's sarcoma models von Bearss, Jared J., Neiss, Adrianne, Liu, Xiao-Hui, Vankayalapati, Hariprasad, Sharma, Sunil

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Abstract 2161: Targeting Bruton's tyrosine kinase (BTK) in multiple myeloma with novel BTK inhibitors von Bushman, Destinee, Bearss, Jared J., Sorna, Venkataswamy, Vankayalapati, Hariprasad, Sharma, Sunil, Zhan, Fenghuang, Bearss, David

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Abstract 2174: Small molecule iInhibitors of PIM kinases as potential treatments for urothelial carcinomas von Carpenter, Kent J., Brog, Rachel, Moreno, Christopher, Albertson, Daniel J., Bearss, Jared J., Liu, Ting, Warner, Steven, Bearss, David J.

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Abstract 5543: Inhibition of the tyrosine kinase receptor Axl blocks cell invasion and promotes apoptosis in pancreatic cancer cells von Anderson, Malia, Ober, Alex, Mollard, Alexis, Call, Lee, Bearss, Jared J., Vankayalapati, Hariprasad, Sharma, Sunil, Warner, Steven, Bearss, David J.

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Abstract 2788: Design, optimization, and biological evaluation of potent irreversible inhibitors of BTK kinase von Bearss, David J., Venkataswamy, Sorna, Warner, Steven L., Vankayalapati, Hariprasad, Bearss, Jared J., Sharma, Sunil

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A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas12 von Foulks, Jason M., Carpenter, Kent J., Luo, Bai, Xu, Yong, Senina, Anna, Nix, Rebecca, Chan, Ashley, Clifford, Adrianne, Wilkes, Marcus, Vollmer, David, Brenning, Benjamin, Merx, Shannon, Lai, Shuping, McCullar, Michael V., Ho, Koc-Kan, Albertson, Daniel J., Call, Lee T., Bearss, Jared J., Tripp, Sheryl, Liu, Ting, Stephens, Bret J., Mollard, Alexis, Warner, Steven L., Bearss, David J., Kanner, Steven B.

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Abstract 2577: Targeting the Axl tyrosine kinase receptor in pancreatic cancer von Call, Lee T., Mollard, Alexis, Wade, Mark L., Bearss, Jared J., Yang, Mei, Verma, Anupam, Vankayalapati, Hariprasad, Hansen, Marc D.H., Bearss, David J., Sharma, Sunil, Warner, Steven L.

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Modulation of NLRP3 Inflammasome in Monocytes By HT-6184 in a Single-Cell Proteomic Study von Bursey, Devan, Bearss, Benjamin, Avei, Taylor, Mollard, Alexis, Bearss, Jared, Janat-Amsbury, Margit Maria, Bearss, David J.

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Ex-Vivo Human Whole Blood Assay for Evaluating the Pharmacodynamics of HT-6184: Reduction in NLRP3 Inflammasome Mediated Cytokine Production von Avei, Taylor, Bursey, Devan, Bearss, Benjamin, Mollard, Alexis, Bearss, Jared, Janat-Amsbury, Margit Maria, Bearss, David J.

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HT-6184 Inhibits the Formation of the NLRP3 Inflammasome in Human Monocytic THP-1 Cells von Bearss, Benjamin, Bursey, Devan, Avei, Taylor, Mollard, Alexis, Bearss, Jared, Janat-Amsbury, Margit Maria, Bearss, David J.

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Fragment-based design, synthesis, biological evaluation, and SAR of 1H-benzo[d]imidazol-2-yl)-1H-indazol derivatives as potent PDK1 inhibitors von Chen, Ting, Sorna, Venkataswamy, Choi, Susie, Call, Lee, Bearss, Jared, Carpenter, Kent, Warner, Steven L., Sharma, Sunil, Bearss, David J., Vankayalapati, Hariprasad

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LSD1 activates a lethal prostate cancer gene network independently of its demethylase function von Sehrawat, Archana, Gao, Lina, Wang, Yuliang, Bankhead, Armand, McWeeney, Shannon K., King, Carly J., Schwartzman, Jacob, Urrutia, Joshua, Bisson, William H., Coleman, Daniel J., Joshi, Sunil K., Kim, Dae-Hwan, Sampson, David A., Weinmann, Sheila, Kallakury, Bhaskar V. S., Berry, Deborah L., Haque, Reina, Van Den Eeden, Stephen K., Sharma, Sunil, Bearss, Jared, Beer, Tomasz M., Thomas, George V., Heiser, Laura M., Alumkal, Joshi J.

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Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort study von Taher, Jennifer, Mighton, Chloe, Chowdhary, Sunakshi, Casalino, Selina, Frangione, Erika, Arnoldo, Saranya, Bearss, Erin, Binnie, Alexandra, Bombard, Yvonne, Borgundvaag, Bjug, Chertkow, Howard, Clausen, Marc, Devine, Luke, Faghfoury, Hanna, Friedman, Steven Marc, Gingras, Anne-Claude, Khan, Zeeshan, Mazzulli, Tony, McGeer, Allison, McLeod, Shelley L, Pugh, Trevor J, Richardson, David, Simpson, Jared, Stern, Seth, Strug, Lisa, Taher, Ahmed, Lerner-Ellis, Jordan

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Fragment-based design, synthesis, biological evaluation, and SAR of 1 H -benzo[ d ]imidazol-2-yl)-1 H -indazol derivatives as potent PDK1 inhibitors von Chen, Ting, Sorna, Venkataswamy, Choi, Susie, Call, Lee, Bearss, Jared, Carpenter, Kent, Warner, Steven L., Sharma, Sunil, Bearss, David J., Vankayalapati, Hariprasad

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Characterizing Risk Factors for Hospitalization and Clinical Characteristics in a Cohort of COVID-19 Patients Enrolled in the GENCOV Study von Morgan, Gregory, Casalino, Selina, Chowdhary, Sunakshi, Frangione, Erika, Fung, Chun Yiu Jordan, Haller, Simona, Lapadula, Elisa, Scott, Mackenzie, Wolday, Dawit, Young, Juliet, Arnoldo, Saranya, Aujla, Navneet, Bearss, Erin, Binnie, Alexandra, Bombard, Yvonne, Borgundvaag, Bjug, Briollais, Laurent, Dagher, Marc, Devine, Luke, Faghfoury, Hanna, Friedman, Steven M, Gingras, Anne-Claude, Goneau, Lee W, Khan, Zeeshan, Mazzulli, Tony, McLeod, Shelley L, Nomigolzar, Romina, Noor, Abdul, Pugh, Trevor J, Richardson, David, Satnam Singh, Harpreet Kaur, Simpson, Jared, Stern, Seth, Strug, Lisa, Taher, Ahmed, Lerner-Ellis, Jordan, Taher, Jennifer

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Genome screening, reporting, and genetic counseling for healthy populations von Casalino, Selina, Frangione, Erika, Chung, Monica, MacDonald, Georgia, Chowdhary, Sunakshi, Mighton, Chloe, Faghfoury, Hanna, Bombard, Yvonne, Strug, Lisa, Pugh, Trevor J., Simpson, Jared, Arnoldo, Saranya, Aujla, Navneet, Bearss, Erin, Binnie, Alexandra, Borgundvaag, Bjug, Chertkow, Howard, Clausen, Marc, Dagher, Marc, Devine, Luke, Di Iorio, David, Friedman, Steven Marc, Fung, Chun Yiu Jordan, Gingras, Anne-Claude, Goneau, Lee W., Kaushik, Deepanjali, Khan, Zeeshan, Lapadula, Elisa, Lu, Tiffany, Mazzulli, Tony, McGeer, Allison, McLeod, Shelley L., Morgan, Gregory, Richardson, David, Singh, Harpreet, Stern, Seth, Taher, Ahmed, Wong, Iris, Zarei, Natasha, Greenfeld, Elena, Hao, Limin, Lebo, Matthew, Lane, William, Noor, Abdul, Taher, Jennifer, Lerner-Ellis, Jordan

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A Genomic Counseling Model for Population-Based Sequencing: A Pre-Post Intervention Study von Casalino, Selina, Mighton, Chloe, Clausen, Marc, Frangione, Erika, Aujla, Navneet, MacDonald, Georgia, Young, Juliet, Fung, Chun Yiu Jordan, Morgan, Gregory, Arnoldo, Saranya, Bearss, Erin, Binnie, Alexandra, Borgundvaag, Bjug, Chowdhary, Sunakshi, Dagher, Marc, Devine, Luke, Friedman, Steven Marc, Hao, Limin, Khan, Zeeshan, Lane, William, Lapadula, Elisa, Lebo, Matthew, Richardson, David, Stern, Seth, Strug, Lisa, Taher, Ahmed, Greenfeld, Elena, Noor, Abdul, Faghfoury, Hanna, Taher, Jennifer, Bombard, Yvonne, Lerner-Ellis, Jordan, Dickson, Brendan, Gingras, Anne-Claude, Goneau, Lee W., Mazzulli, Tony, McGeer, Allison, McLeod, Shelley, Pugh, Trevor J., Simpson, Jared

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