Design, Synthesis, and Biological Evaluation of a Series of Novel AXL Kinase Inhibitors von Mollard, Alexis, Warner, Steven L, Call, Lee T, Wade, Mark L, Bearss, Jared J, Verma, Anupam, Sharma, Sunil, Vankayalapati, Hariprasad, Bearss, David J

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Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia von Park, I-K, Mundy-Bosse, B, Whitman, S P, Zhang, X, Warner, S L, Bearss, D J, Blum, W, Marcucci, G, Caligiuri, M A

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A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas von Foulks, Jason M, Carpenter, Kent J, Luo, Bai, Xu, Yong, Senina, Anna, Nix, Rebecca, Chan, Ashley, Clifford, Adrianne, Wilkes, Marcus, Vollmer, David, Brenning, Benjamin, Merx, Shannon, Lai, Shuping, McCullar, Michael V, Ho, Koc-Kan, Albertson, Daniel J, Call, Lee T, Bearss, Jared J, Tripp, Sheryl, Liu, Ting, Stephens, Bret J, Mollard, Alexis, Warner, Steven L, Bearss, David J, Kanner, Steven B

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription von Siddiqui-Jain, Adam, Grand, Cory L., Bearss, David J., Hurley, Laurence H.

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Chemical Genetic Screen Reveals a Role for Desmosomal Adhesion in Mammary Branching Morphogenesis von Basham, Kaitlin J., Kieffer, Collin, Shelton, Dawne N., Leonard, Christopher J., Bhonde, Vasudev R., Vankayalapati, Hariprasad, Milash, Brett, Bearss, David J., Looper, Ryan E., Welm, Bryan E.

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High-Throughput Virtual Screening Identifies Novel N′‑(1-Phenylethylidene)-benzohydrazides as Potent, Specific, and Reversible LSD1 Inhibitors von Sorna, Venkataswamy, Theisen, Emily R, Stephens, Bret, Warner, Steven L, Bearss, David J, Vankayalapati, Hariprasad, Sharma, Sunil

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Targeting Axl and Mer kinases in cancer von Verma, Anupam, Warner, Steven L, Vankayalapati, Hariprasad, Bearss, David J, Sharma, Sunil

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An Epithelial―Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resista... von AVERETT BYERS, Lauren, LIXIA DIAO, NILSSON, Monique B, GUDIKOTE, Jayanthi, TRAN, Hai, CARDNELL, Robert J. G, BEARSS, David J, WARNER, Steven L, FOULKS, Jason M, KANNER, Steven B, GANDHI, Varsha, KRETT, Nancy, JING WANG, ROSEN, Steven T, KIM, Edward S, HERBST, RoyS, BLUMENSCHEIN, George R, LEE, J. Jack, LIPPMAN, Scott M, KIAN ANG, K, MILLS, Gordon B, HONG, Waun K, WEINSTEIN, John N, SAINTIGNY, Pierre, WISTUBA, Ignacio I, COOMBES, Kevin R, MINNA, John D, HEYMACH, John V, GIRARD, Luc, PEYTON, Michael, LI SHEN, YOUHONG FAN, GIRI, Uma, TUMULA, Praveen K

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Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma von Sankar, S, Bell, R, Stephens, B, Zhuo, R, Sharma, S, Bearss, D J, Lessnick, S L

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Shining the light on aurora-a kinase as a drug target in pancreatic cancer von Bearss, David J

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Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer von Gray, Jr, Phillip J, Bearss, David J, Han, Haiyong, Nagle, Raymond, Tsao, Ming-Sound, Dean, Nicholas, Von Hoff, Daniel D

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Smallpox lesion characterization in placebo-treated and tecovirimat-treated macaques using traditional and novel methods von Bell, Todd M, Facemire, Paul, Bearss, Jeremy J, Raymond, Jo Lynne, Chapman, Jennifer, Zeng, Xiankun, Shamblin, Joshua D, Williams, Janice A, Grosenbach, Douglas W, Hruby, Dennis E, Damon, Inger K, Goff, Arthur J, Mucker, Eric M

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Immune-Mediated Systemic Vasculitis as the Proposed Cause of Sudden-Onset Sensorineural Hearing Loss following Lassa Virus Exposure in Cynomolgus Macaques von Cashman, Kathleen A, Wilkinson, Eric R, Zeng, Xiankun, Cardile, Anthony P, Facemire, Paul R, Bell, Todd M, Bearss, Jeremy J, Shaia, Carl I, Schmaljohn, Connie S

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EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics von Bearss, Jeremiah J, Padi, Sathish KR, Singh, Neha, Cardo-Vila, Marina, Song, Jin H, Mouneimne, Ghassan, Fernandes, Nikita, Li, Yang, Harter, Matthew R, Gard, Jaime MC, Cress, Anne E, Peti, Wolfgang, Nelson, Andrew DL, Buchan, J Ross, Kraft, Andrew S, Okumura, Koichi

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S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth von Chuang, Jody C, Warner, Steven L, Vollmer, David, Vankayalapati, Hariprasad, Redkar, Sanjeev, Bearss, David J, Qiu, Xiangning, Yoo, Christine B, Jones, Peter A

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Use of a bacteriophage lysin to identify a novel target for antimicrobial development von Schuch, Raymond, Pelzek, Adam J, Raz, Assaf, Euler, Chad W, Ryan, Patricia A, Winer, Benjamin Y, Farnsworth, Andrew, Bhaskaran, Shyam S, Stebbins, C Erec, Xu, Yong, Clifford, Adrienne, Bearss, David J, Vankayalapati, Hariprasad, Goldberg, Allan R, Fischetti, Vincent A

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TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth von Chan, Tsz-Yin, Egbert, Christina M., Maxson, Julia E., Siddiqui, Adam, Larsen, Logan J., Kohler, Kristina, Balasooriya, Eranga Roshan, Pennington, Katie L., Tsang, Tsz-Ming, Frey, Madison, Soderblom, Erik J., Geng, Huimin, Müschen, Markus, Forostyan, Tetyana V., Free, Savannah, Mercenne, Gaelle, Banks, Courtney J., Valdoz, Jonard, Whatcott, Clifford J., Foulks, Jason M., Bearss, David J., O’Hare, Thomas, Huang, David C. S., Christensen, Kenneth A., Moody, James, Warner, Steven L., Tyner, Jeffrey W., Andersen, Joshua L.

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Characterization of Burkholderia pseudomallei Strains Using a Murine Intraperitoneal Infection Model and In Vitro Macrophage Assays von Welkos, Susan L, Klimko, Christopher P, Kern, Steven J, Bearss, Jeremy J, Bozue, Joel A, Bernhards, Robert C, Trevino, Sylvia R, Waag, David M, Amemiya, Kei, Worsham, Patricia L, Cote, Christopher K

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PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth von Singh, Neha, Padi, Sathish K. R., Bearss, Jeremiah J., Pandey, Ritu, Okumura, Koichi, Beltran, Himisha, Song, Jin H., Kraft, Andrew S., Olive, Virginie

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The tumor suppressor axis p53/miR-34a regulates Axl expression in B-cell chronic lymphocytic leukemia: implications for therapy in p53-defective CLL patients von Boysen, J, Sinha, S, Price-Troska, T, Warner, S L, Bearss, D J, Viswanatha, D, Shanafelt, T D, Kay, N E, Ghosh, A K

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