Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity von Chen, Han, Beardsley, G. Peter, Coen, Donald M.

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Expression of HER2/erbB-2 Correlates With Survival in Osteosarcoma von GORLICK, R, HUVOS, A. G, HELLER, G, ALEDO, A, BEARDSLEY, G. P, HEALEY, J. H, MEYERS, P. A

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LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes von SHIH, C, CHEN, V. J, ANDIS, S. L, BEWLEY, J. R, RAYL, E. A, MOROSON, B. A, BEARDSLEY, G. P, KOHLER, W, RATNAM, M, SCHULTZ, R. M, GOSSETT, L. S, GATES, S. B, MACKELLAR, W. C, HABECK, L. L, SHACKELFORD, K. A, MENDELSOHN, L. G, SOOSE, D. J, PATEL, V. F

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Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: Meeting summary von GORLICK, Richard, ANDERSON, Peter, GARDNER, Thomas, GEBHARDT, Mark, GRIER, Holcombe, HANSEN, Marc, HEALEY, John, HELMAN, Lee, HOCK, Janet, HOUGHTON, Janet, HOUGHTON, Peter, HUVOS, Andrew, ANDRULIS, Irene, KHANNA, Chand, KIERAN, Mark, KIEINERMAN, Eugenic, LADANYI, Marc, LAU, Ching, MALKIN, David, MARINA, Neyssa, MELTZER, Paul, MEYERS, Paul, SCHOFIELD, Deborah, ARNDT, Carola, SCHWARTZ, Cindy, SMITH, Malcolm A, TORETSKY, Jeffrey, TSOKOS, Maria, WEXLER, Leonard, WIGGINTON, Jon, WITHROW, Stephen, SCHOENFELDT, Mason, ANDERSON, Barry, BEARDSLEY, G. Peter, BERNSTEIN, Mark, BRIDGE, Julia, CHEUNG, Nai-Kong, DOME, Jeffrey S, EBB, David

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Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis von Wilson, Ian A, Greasley, Samantha E, Horton, Patricia, Ramcharan, Joseph, Beardsley, G. Peter, Benkovic, Stephen J

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Crystal Structures of Human Bifunctional Enzyme Aminoimidazole-4-carboxamide Ribonucleotide Transformylase/IMP Cyclohydrolase in Complex with Potent Sulfonyl-containing Antifolates von Cheong, Cheom-Gil, Wolan, Dennis W., Greasley, Samantha E., Horton, Patricia A., Beardsley, G. Peter, Wilson, Ian A.

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Oblique collision and accretion of the Netherlands Leeward Antilles to South America von Beardsley, A. G., Avé Lallemant, H. G.

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The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lac... von Bulock, Karen G, Beardsley, G Peter, Anderson, Karen S

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Sequence Alterations in the Reduced Folate Carrier Are Observed in Osteosarcoma Tumor Samples von RUI YANG, SOWERS, Rebecca, BERTINO, Joseph R, MEYERS, Paul A, GORLICK, Richard, MAZZA, Bethanne, HEALEY, John H, HUVOS, Andrew, GRIER, Holcombe, BERNSTEIN, Mark, BEARDSLEY, G. Peter, KRAILO, Mark D, DEVIDAS, Meenakshi

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Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase von Xu, Lan, Chong, Youhoon, Hwang, Inkyu, D'Onofrio, Anthony, Amore, Kristen, Beardsley, G. Peter, Li, Chenglong, Olson, Arthur J., Boger, Dale L., Wilson, Ian A.

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Catalytic Mechanism of the Cyclohydrolase Activity of Human Aminoimidazole Carboxamide Ribonucleotide Formyltransferase/Inosine Monophosphate Cyclohydrolase von Vergis, James M, Beardsley, G. Peter

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Structural Insights into the Avian AICAR Transformylase Mechanism von Wolan, Dennis W, Greasley, Samantha E, Beardsley, G. Peter, Wilson, Ian A

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Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activit... von Vergis, J M, Bulock, K G, Fleming, K G, Beardsley, G P

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Laboratory evaluation of rapid test kits to detect hepatitis C antibody for use in predonation screening in emergency settings von O'Connell, Robert J., Gates, Robert G., Bautista, Christian T., Imbach, Michelle, Eggleston, John C., Beardsley, Stephen G., Manak, Mark M., Gonzales, Richard, Rentas, Francisco J., Macdonald, Victor W., Cardo, Lisa J., Reiber, David T., Stramer, Susan L., Michael, Nelson L., Peel, Sheila A.

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Crystal Structures of Human GAR Tfase at Low and High pH and with Substrate β-GAR von Zhang, Yan, Desharnais, Joel, Greasley, Samantha E, Beardsley, G. Peter, Boger, Dale L, Wilson, Ian A

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Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity von Chen, Han, Beardsley, G. Peter, Coen, Donald

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A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis von Beardsley, G P, Moroson, B A, Taylor, E C, Moran, R G

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The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, an... von Rayl, E A, Moroson, B A, Beardsley, G P

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Functional consequences of the arabinosylcytosine structural lesion in DNA von Mikita, Thomas, Beardsley, G. Peter

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Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM von PIZZORNO, G, MOROSON, B. A, CASHMORE, A. R, RUSSELLO, O, MAYER, J. R, GALIVAN, J, BUNNI, M. A, PRIEST, D. G, BEARDSLEY, G. P

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