Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy von Bautista-Aguilera, Oscar M., Ismaili, Lhassane, Chioua, Mourad, Andrys, Rudolf, Schmidt, Monika, Bzonek, Petr, Angeles Martinez-Grau, Maria, Beadle, Christopher D., Vetman, Tatiana, Lopez-Munoz, Francisco, Iriepa, Isabel, Refouvelet, Bernard, Musilek, Kamil, Marco-Contelles, Jose

Volltext

Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S‑2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metab... von Monn, James A, Prieto, Lourdes, Taboada, Lorena, Pedregal, Concepcion, Hao, Junliang, Reinhard, Matt R, Henry, Steven S, Goldsmith, Paul J, Beadle, Christopher D, Walton, Lesley, Man, Teresa, Rudyk, Helene, Clark, Barry, Tupper, David, Baker, S. Richard, Lamas, Carlos, Montero, Carlos, Marcos, Alicia, Blanco, Jaime, Bures, Mark, Clawson, David K, Atwell, Shane, Lu, Frances, Wang, Jing, Russell, Marijane, Heinz, Beverly A, Wang, Xushan, Carter, Joan H, Xiang, Chuanxi, Catlow, John T, Swanson, Steven, Sanger, Helen, Broad, Lisa M, Johnson, Michael P, Knopp, Kelly L, Simmons, Rosa M. A, Johnson, Bryan G, Shaw, David B, McKinzie, David L

Volltext

Synthesis and Pharmacological Characterization of C4‑(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)‑2-Amino-4-(1H‑1,... von Monn, James A, Prieto, Lourdes, Taboada, Lorena, Hao, Junliang, Reinhard, Matthew R, Henry, Steven S, Beadle, Christopher D, Walton, Lesley, Man, Teresa, Rudyk, Helene, Clark, Barry, Tupper, David, Baker, S. Richard, Lamas, Carlos, Montero, Carlos, Marcos, Alicia, Blanco, Jaime, Bures, Mark, Clawson, David K, Atwell, Shane, Lu, Frances, Wang, Jing, Russell, Marijane, Heinz, Beverly A, Wang, Xushan, Carter, Joan H, Getman, Brian G, Catlow, John T, Swanson, Steven, Johnson, Bryan G, Shaw, David B, McKinzie, David L

Volltext

Chromenones as Multineurotargeting Inhibitors of Human Enzymes von Lemke, Carina, Christmann, Joscha, Yin, Jiafei, Alonso, José M, Serrano, Estefanía, Chioua, Mourad, Ismaili, Lhassane, Martínez-Grau, María Angeles, Beadle, Christopher D, Vetman, Tatiana, Dato, Florian M, Bartz, Ulrike, Elsinghorst, Paul W, Pietsch, Markus, Müller, Christa E, Iriepa, Isabel, Wille, Timo, Marco-Contelles, José, Gütschow, Michael

Volltext

Synthesis and Pharmacological Characterization of 2‑(2,6-Dichlorophenyl)-1-((1S,3R)‑5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)‑yl)ethan-1-o... von Hao, Junliang, Beck, James P, Schaus, John M, Krushinski, Joseph H, Chen, Qi, Beadle, Christopher D, Vidal, Paloma, Reinhard, Matthew R, Dressman, Bruce A, Massey, Steven M, Boulet, Serge L, Cohen, Michael P, Watson, Brian M, Tupper, David, Gardinier, Kevin M, Myers, Jason, Johansson, Anette M, Richardson, Jeffery, Richards, Daniel S, Hembre, Erik J, Remick, David M, Coates, David A, Bhardwaj, Rajni M, Diseroad, Benjamin A, Bender, David, Stephenson, Greg, Wolfangel, Craig D, Diaz, Nuria, Getman, Brian G, Wang, Xu-shan, Heinz, Beverly A, Cramer, Jeff W, Zhou, Xin, Maren, Deanna L, Falcone, Julie F, Wright, Rebecca A, Mitchell, Stephen N, Carter, Guy, Yang, Charles R, Bruns, Robert F, Svensson, Kjell A

Volltext

The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents von Keuler, Tim, Lemke, Carina, Elsinghorst, Paul W., Iriepa, Isabel, Chioua, Mourad, Martínez-Grau, María Angeles, Beadle, Christopher D., Vetman, Tatiana, López-Muñoz, Francisco, Wille, Timo, Bartz, Ulrike, Deuther-Conrad, Winnie, Marco-Contelles, José, Gütschow, Michael

Volltext

1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors von Beadle, Christopher D, Boot, John, Camp, Nicholas P, Dezutter, Nancy, Findlay, Jeremy, Hayhurst, Lorna, Masters, John J, Penariol, Roberta, Walter, Magnus W

Volltext

Investigation of a Flexible Enantiospecific Approach to Aziridines von Jamookeeah, Clare E, Beadle, Christopher D, Jackson, Richard F. W, Harrity, Joseph P. A

Volltext

1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors von BEADLE, Christopher D, BOOT, John, CAMP, Nicholas P, DEZUTTER, Nancy, FINDLAY, Jeremy, HAYHURST, Lorna, MASTERS, John J, PENARIOL, Roberta, WALTER, Magnus W

Volltext

Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,... von Monn, James A., Prieto, Lourdes, Taboada, Lorena, Hao, Junliang, Reinhard, Matthew R., Henry, Steven S., Beadle, Christopher D., Walton, Lesley, Man, Teresa, Rudyk, Helene, Clark, Barry, Tupper, David, Baker, S. Richard, Lamas, Carlos, Montero, Carlos, Marcos, Alicia, Blanco, Jaime, Bures†, Mark, Clawson, David K., Atwell, Shane, Lu, Frances, Wang, Jing, Russell, Marijane, Heinz, Beverly A., Wang, Xushan, Carter, Joan H., Getman, Brian G., Catlow, John T., Swanson, Steven, Johnson, Bryan G., Shaw, David B., McKinzie, David L.

Volltext

Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1 S ,2 S ,5 R ,6 S -2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selecti... von Monn, James A., Prieto, Lourdes, Taboada, Lorena, Pedregal, Concepcion, Hao, Junliang, Reinhard, Matt R., Henry, Steven S., Goldsmith, Paul J., Beadle, Christopher D., Walton, Lesley, Man, Teresa, Rudyk, Helene, Clark, Barry, Tupper, David, Baker, S. Richard, Lamas, Carlos, Montero, Carlos, Marcos, Alicia, Blanco, Jaime, Bures, Mark, Clawson, David K., Atwell, Shane, Lu, Frances, Wang, Jing, Russell, Marijane, Heinz, Beverly A., Wang, Xushan, Carter, Joan H., Xiang, Chuanxi, Catlow, John T., Swanson, Steven, Sanger, Helen, Broad, Lisa M., Johnson, Michael P., Knopp, Kelly L., Simmons, Rosa M. A., Johnson, Bryan G., Shaw, David B., McKinzie, David L.

Volltext

Automated Synthesis of New Quinoxalinetacrines von Bautista‐Aguilera, Óscar M., Ismaili, Lhassane, Chioua, Mourad, Iriepa, Isabel, Ángeles Martinez‐Grau, Marìa, Beadle, Christopher D., Vetman, Tatiana, López‐Muñoz, Francisco, Marco‐Contelles, José

Volltext

Synthesis and Pharmacological Characterization of C 4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 R ,2 S ,4 R ,5 R ,6 R )-2-Ami... von Monn, James A., Prieto, Lourdes, Taboada, Lorena, Hao, Junliang, Reinhard, Matthew R., Henry, Steven S., Beadle, Christopher D., Walton, Lesley, Man, Teresa, Rudyk, Helene, Clark, Barry, Tupper, David, Baker, S. Richard, Lamas, Carlos, Montero, Carlos, Marcos, Alicia, Blanco, Jaime, Bures, Mark, Clawson, David K., Atwell, Shane, Lu, Frances, Wang, Jing, Russell, Marijane, Heinz, Beverly A., Wang, Xushan, Carter, Joan H., Getman, Brian G., Catlow, John T., Swanson, Steven, Johnson, Bryan G., Shaw, David B., McKinzie, David L.

Volltext

1-Aryl-3,4-dihydro-1 H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors von Beadle, Christopher D., Boot, John, Camp, Nicholas P., Dezutter, Nancy, Findlay, Jeremy, Hayhurst, Lorna, Masters, John J., Penariol, Roberta, Walter, Magnus W.

Volltext

ChemInform Abstract: Investigation of a Flexible Enantiospecific Approach to Aziridines von Jamookeeah, Clare E., Beadle, Christopher D., Jackson, Richard F. W., Harrity, Joseph P. A.

Volltext

Quinolone derivatives von BEADLE CHRISTOPHER D, PENARIOL ROBERTA, CAMP NICHOLAS P

Volltext bestellen

1-Aryl-3,4-dihydro-1H-quinolin-2-one Derivatives, Novel and Selective Norepinephrine Reuptake Inhibitors von Beadle, Christopher D., Boot, John, Camp, Nicholas P., Dezutter, Nancy, Findlay, Jeremy, Hayhurst, Lorna, Masters, John J., Penariol, Roberta, Walter, Magnus W.

Volltext

3-AMINOPYRROLIDINES AS INHIBITORS OF MONOAMINE UPTAKE von MASTERS, JOHN, JOSEPH, CASES-THOMAS, M. J, WHATTON, MARIA, ANN, WOOD, VIRGINIA, ANN, CLARK, BARRY, PETER, GALLAGHER, PETER, T, GILMORE, JEREMY, TIMMS, GRAHAM, HENRY, WALTER, MAGNUS, W, BEADLE, CHRISTOPHER, D

Volltext bestellen

3-Aminopiperidines and 3-aminoquinuclidines as inhibitors of monoamine uptake von CLARK BARRY, GALLAGHER PETER T, WALTER MAGNUS W, WOOD VIRGINIA A, WHATTON MARIA A, MASTERS JOHN J, BEADLE CHRISTOPHER D, GILMORE JEREMY, TIMMS GRAHAM H, CASES-THOMAS MANUEL J

Volltext bestellen

3-Aminopyrrolidines as inhibitors of monoamine uptake von CLARK BARRY P, GALLAGHER PETER T, WALTER MAGNUS W, WOOD VIRGINIA A, WHATTON MARIA A, MASTERS JOHN J, BEADLE CHRISTOPHER D, GILMORE JEREMY, TIMMS GRAHAM H, CASESTHOMAS MANUEL J

Volltext bestellen