Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells von Alcaraz, Estefania, Vilardell, Jordi, Borgo, Christian, Sarró, Eduard, Plana, Maria, Marin, Oriano, Pinna, Lorenzo A, Bayascas, José R, Meseguer, Anna, Salvi, Mauro, Itarte, Emilio, Ruzzene, Maria

Volltext

MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes von Soriano, Aroa, París-Coderch, Laia, Jubierre, Luz, Martínez, Alba, Zhou, Xiangyu, Piskareva, Olga, Bray, Isabella, Vidal, Isaac, Almazán-Moga, Ana, Molist, Carla, Roma, Josep, Bayascas, José R, Casanovas, Oriol, Stallings, Raymond L, Sánchez de Toledo, José, Gallego, Soledad, Segura, Miguel F

Volltext

The Contribution of Apoptosis-inducing Factor, Caspase-activated DNase, and Inhibitor of Caspase-activated DNase to the Nuclear Phenotype and DNA Degradation during Apoptosis von Yuste, Victor J., Sánchez-López, Isabel, Solé, Carme, Moubarak, Rana S., Bayascas, José R., Dolcet, Xavier, Encinas, Mario, Susin, Santos A., Comella, Joan X.

Volltext

LKB1-dependent signaling pathways von Alessi, Dario R, Sakamoto, Kei, Bayascas, Jose R

Volltext

Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways von Bayascas, Jose R.

Volltext

Regulation of Akt/PKB Ser473 Phosphorylation von Bayascas, Jose R., Alessi, Dario R.

Volltext

Phosphoinositide (3,4,5)-Triphosphate Binding to Phosphoinositide-Dependent Kinase 1 Regulates a Protein Kinase B/Akt Signaling Threshold That Dictates T-Cell Migration, Not Prolif... von Waugh, Caryll, Sinclair, Linda, Finlay, David, Bayascas, Jose R., Cantrell, Doreen

Volltext

Canonical and Kinase Activity-Independent Mechanisms for Extracellular Signal-Regulated Kinase 5 (ERK5) Nuclear Translocation Require Dissociation of Hsp90 from the ERK5-Cdc37 Comp... von Erazo, Tatiana, Moreno, Ana, Ruiz-Babot, Gerard, Rodríguez-Asiain, Arantza, Morrice, Nicholas A, Espadamala, Josep, Bayascas, Jose R, Gómez, Nestor, Lizcano, Jose M

Volltext

Hypomorphic Mutation of PDK1 Suppresses Tumorigenesis in PTEN+/− Mice von Bayascas, Jose R., Leslie, Nick R., Parsons, Ramon, Fleming, Stewart, Alessi, Dario R.

Volltext

Interaction of PDK1 with Phosphoinositides Is Essential for Neuronal Differentiation but Dispensable for Neuronal Survival von Zurashvili, Tinatin, Cordón-Barris, Lluís, Ruiz-Babot, Gerard, Zhou, Xiangyu, Lizcano, Jose M, Gómez, Nestor, Giménez-Llort, Lydia, Bayascas, Jose R

Volltext

Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides von Yang, Shaobin, Pascual-Guiral, Sònia, Ponce, Rebeca, Giménez-Llort, Lydia, Baltrons, María A, Arancio, Ottavio, Palacio, Jose R, Clos, Victoria M, Yuste, Victor J, Bayascas, Jose R

Volltext

Capturing conformational transitions of full-length PDK1 that dictate kinase substrate selectivity von Martínez-Arenas, Laura, Bayascas, Jose R

Volltext

Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance von Bayascas, Jose R., Wullschleger, Stephan, Sakamoto, Kei, García-Martínez, Juan M., Clacher, Carol, Komander, David, van Aalten, Daan M. F., Boini, Krishna M., Lang, Florian, Lipina, Christopher, Logie, Lisa, Sutherland, Calum, Chudek, John A., van Diepen, Janna A., Voshol, Peter J., Lucocq, John M., Alessi, Dario R.

Volltext

The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival von Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Yoldi, Guillermo, Megías-Roda, Elisabet, Bolinaga-Ayala, Idoia, Viñas-Casas, Maria, Gorgisen, Gokhan, Domingo-Ortí, Inés, Pérez-Montoyo, Héctor, Bayascas, Jose R., Colas, Eva, Dolcet, Xavier, Lizcano, Jose M.

Volltext

Receptors of the Glial Cell Line-Derived Neurotrophic Factor Family of Neurotrophic Factors Signal Cell Survival through the Phosphatidylinositol 3-Kinase Pathway in Spinal Cord Mo... von Soler, Rosa M, Dolcet, Xavier, Encinas, Mario, Egea, Joaquim, Bayascas, Jose R, Comella, Joan X

Volltext

Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independen... von Cordón-Barris, Lluís, Pascual-Guiral, Sònia, Yang, Shaobin, Giménez-Llort, Lydia, Lope-Piedrafita, Silvia, Niemeyer, Carlota, Claro, Enrique, Lizcano, Jose M., Bayascas, Jose R.

Volltext

Evaluation of Approaches to Generation of Tissue-specific Knock-in Mice von Bayascas, Jose R., Sakamoto, Kei, Armit, Laura, Arthur, J. Simon C., Alessi, Dario R.

Volltext

Correction for Zurashvili et al., Interaction of PDK1 with Phosphoinositides Is Essential for Neuronal Differentiation but Dispensable for Neuronal Survival von Zurashvili, Tinatin, Cordón-Barris, Lluís, Ruiz-Babot, Gerard, Zhou, Xiangyu, Lizcano, Jose M, Gómez, Nestor, Giménez-Llort, Lydia, Bayascas, Jose R

Volltext

Gossypol Treatment Restores Insufficient Apoptotic Function of DFF40/CAD in Human Glioblastoma Cells von Martínez-Escardó, Laura, Alemany, Montse, Sánchez-Osuna, María, Sánchez-Chardi, Alejandro, Roig-Martínez, Meritxell, Suárez-García, Salvio, Ruiz-Molina, Daniel, Vidal, Noemi, Plans, Gerard, Majós, Carles, Ribas, Judit, Baltrons, María Antonia, Bayascas, Jose R., Barcia, Carlos, Bruna, Jordi, Yuste, Victor J.

Volltext

Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation von Sanchez Canedo, Cossette, Demeulder, Bénédicte, Ginion, Audrey, Bayascas, Jose R, Balligand, Jean-Luc, Alessi, Dario R, Vanoverschelde, Jean-Louis, Beauloye, Christophe, Hue, Louis, Bertrand, Luc

Volltext