Genetic Disorders of the Extracellular Matrix von Lamandé, Shireen R., Bateman, John F.

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The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis von Gossan, Nicole, Zeef, Leo, Hensman, James, Hughes, Alun, Bateman, John F., Rowley, Lynn, Little, Christopher B., Piggins, Hugh D., Rattray, Magnus, Boot‐Handford, Raymond P., Meng, Qing‐Jun

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Increased intracellular proteolysis reduces disease severity in an ER stress-associated dwarfism von Mullan, Lorna A, Mularczyk, Ewa J, Kung, Louise H, Forouhan, Mitra, Wragg, Jordan Ma, Goodacre, Royston, Bateman, John F, Swanton, Eileithyia, Briggs, Michael D, Boot-Handford, Raymond P

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Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis von Kung, Louise H W, Mullan, Lorna, Soul, Jamie, Wang, Ping, Mori, Kazutoshi, Bateman, John F, Briggs, Michael D, Boot-Handford, Raymond P

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Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection von Ishida, Yoshihito, Yamamoto, Akitsugu, Kitamura, Akira, Lamandé, Shireen R, Yoshimori, Tamotsu, Bateman, John F, Kubota, Hiroshi, Nagata, Kazuhiro

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Generation of a heterozygous COL2A1 (p.G1113C) hypochondrogenesis mutation iPSC line, MCRIi019-A-7, using CRISPR/Cas9 gene editing von Lilianty, Jinia, Bateman, John F., Lamandé, Shireen R.

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Collagen VI disorders: Insights on form and function in the extracellular matrix and beyond von Lamandé, Shireen R., Bateman, John F.

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Targeted induction of endoplasmic reticulum stress induces cartilage pathology von Rajpar, M Helen, McDermott, Ben, Kung, Louise, Eardley, Rachel, Knowles, Lynette, Heeran, Mel, Thornton, David J, Wilson, Richard, Bateman, John F, Poulsom, Richard, Arvan, Peter, Kadler, Karl E, Briggs, Michael D, Boot-Handford, Raymond P

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Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis von Bernardo, Bianca C., Belluoccio, Daniele, Rowley, Lynn, Little, Christopher B., Hansen, Uwe, Bateman, John F.

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XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease von Piróg, Katarzyna A, Dennis, Ella P, Hartley, Claire L, Jackson, Robert M, Soul, Jamie, Schwartz, Jean-Marc, Bateman, John F, Boot-Handford, Raymond P, Briggs, Michael D

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Mutations in TRPV4 cause an inherited arthropathy of hands and feet von Lamandé, Shireen R, Yuan, Yuan, Gresshoff, Irma L, Rowley, Lynn, Belluoccio, Daniele, Kaluarachchi, Kumara, Little, Christopher B, Botzenhart, Elke, Zerres, Klaus, Amor, David J, Cole, William G, Savarirayan, Ravi, McIntyre, Peter, Bateman, John F

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Transcriptomics of Wild‐Type Mice and Mice Lacking ADAMTS‐5 Activity Identifies Genes Involved in Osteoarthritis Initiation and Cartilage Destruction von Bateman, John F., Rowley, Lynn, Belluoccio, Daniele, Chan, Ben, Bell, Katrina, Fosang, Amanda J., Little, Christopher B.

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Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis von Yammine, Kathryn M., Mirda Abularach, Sophia, Sampurno, Lisa, Bateman, John F., Lamandé, Shireen R., Shoulders, Matthew D.

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Cauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndrome von Miller, Kerry A, Ah-Cann, Casey J, Welfare, Megan F, Tan, Tiong Y, Pope, Kate, Caruana, Georgina, Freckmann, Mary-Louise, Savarirayan, Ravi, Bertram, John F, Dobbie, Michael S, Bateman, John F, Farlie, Peter G

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Changes in the Chondrocyte and Extracellular Matrix Proteome during Post-natal Mouse Cartilage Development von Wilson, Richard, Norris, Emma L., Brachvogel, Bent, Angelucci, Constanza, Zivkovic, Snezana, Gordon, Lavinia, Bernardo, Bianca C., Stermann, Jacek, Sekiguchi, Kiyotoshi, Gorman, Jeffrey J., Bateman, John F.

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XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease von Cameron, Trevor L, Bell, Katrina M, Gresshoff, Irma L, Sampurno, Lisa, Mullan, Lorna, Ermann, Joerg, Glimcher, Laurie H, Boot-Handford, Raymond P, Bateman, John F

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Nonsense-mediated mRNA decay of collagen -emerging complexity in RNA surveillance mechanisms von Fang, Yiwen, Bateman, John F, Mercer, Julian F, Lamandé, Shireen R

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CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A von Kung, Louise H.W., Sampurno, Lisa, Yammine, Kathryn M., Graham, Alison, McDonald, Penny, Bateman, John F., Shoulders, Matthew D., Lamandé, Shireen R.

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Complexes of Matrilin-1 and Biglycan or Decorin Connect Collagen VI Microfibrils to Both Collagen II and Aggrecan von Wiberg, Charlotte, Klatt, Andreas R., Wagener, Raimund, Paulsson, Mats, Bateman, John F., Heinegård, Dick, Mörgelin, Matthias

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Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing von Hosseini Far, Hani, Patria, Yudha Nur, Motazedian, Ali, Elefanty, Andrew G., Stanley, Edouard G., Lamandé, Shireen R., Bateman, John F.

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