Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer von Kim, Seung Tae, Cristescu, Razvan, Bass, Adam J., Kim, Kyoung-Mee, Odegaard, Justin I., Kim, Kyung, Liu, Xiao Qiao, Sher, Xinwei, Jung, Hun, Lee, Mijin, Lee, Sujin, Park, Se Hoon, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Lee, Hyuk, Choi, Mingew, Talasaz, AmirAli, Kang, Peter Soonmo, Cheng, Jonathan, Loboda, Andrey, Lee, Jeeyun, Kang, Won Ki

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IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment von Karakasheva, Tatiana A, Lin, Eric W, Tang, Qiaosi, Qiao, Edmund, Waldron, Todd J, Soni, Monica, Klein-Szanto, Andres J, Sahu, Varun, Basu, Devraj, Ohashi, Shinya, Baba, Kiichiro, Giaccone, Zachary T, Walker, Sarah R, Frank, David A, Wileyto, E Paul, Long, Qi, Dunagin, Margaret C, Raj, Arjun, Diehl, J Alan, Wong, K K, Bass, Adam J, Rustgi, Anil K

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Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis von Rampal, Raajit, Al-Shahrour, Fatima, Abdel-Wahab, Omar, Patel, Jay P., Brunel, Jean-Philippe, Mermel, Craig H., Bass, Adam J., Pretz, Jennifer, Ahn, Jihae, Hricik, Todd, Kilpivaara, Outi, Wadleigh, Martha, Busque, Lambert, Gilliland, D. Gary, Golub, Todd R., Ebert, Benjamin L., Levine, Ross L.

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Genomics and Targeted Therapies in Gastroesophageal Adenocarcinoma von Nagaraja, Ankur K, Kikuchi, Osamu, Bass, Adam J

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Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma von Natsuizaka, Mitsuteru, Whelan, Kelly A., Kagawa, Shingo, Tanaka, Koji, Giroux, Veronique, Chandramouleeswaran, Prasanna M., Long, Apple, Sahu, Varun, Darling, Douglas S., Que, Jianwen, Yang, Yizeng, Katz, Jonathan P., Wileyto, E. Paul, Basu, Devraj, Kita, Yoshiaki, Natsugoe, Shoji, Naganuma, Seiji, Klein-Szanto, Andres J., Diehl, J. Alan, Bass, Adam J., Wong, Kwok-Kin, Rustgi, Anil K., Nakagawa, Hiroshi

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Paired exome analysis of Barrett's esophagus and adenocarcinoma von Stachler, Matthew D, Taylor-Weiner, Amaro, Peng, Shouyong, McKenna, Aaron, Agoston, Agoston T, Odze, Robert D, Davison, Jon M, Nason, Katie S, Loda, Massimo, Leshchiner, Ignaty, Stewart, Chip, Stojanov, Petar, Seepo, Sara, Lawrence, Michael S, Ferrer-Torres, Daysha, Lin, Jules, Chang, Andrew C, Gabriel, Stacey B, Lander, Eric S, Beer, David G, Getz, Gad, Carter, Scott L, Bass, Adam J

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Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression von Xu, Chunxiao, Fillmore, Christine M., Koyama, Shohei, Wu, Hongbo, Zhao, Yanqiu, Chen, Zhao, Herter-Sprie, Grit S., Akbay, Esra A., Tchaicha, Jeremy H., Altabef, Abigail, Reibel, Jacob B., Walton, Zandra, Ji, Hongbin, Watanabe, Hideo, Jänne, Pasi A., Castrillon, Diego H., Rustgi, Anil K., Bass, Adam J., Freeman, Gordon J., Padera, Robert F., Dranoff, Glenn, Hammerman, Peter S., Kim, Carla F., Wong, Kwok-Kin

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Detection of Mutations in Barrett’s Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma von Stachler, Matthew D., Camarda, Nicholas D., Deitrick, Christopher, Kim, Anthony, Agoston, Agoston T., Odze, Robert D., Hornick, Jason L., Nag, Anwesha, Thorner, Aaron R., Ducar, Matthew, Noffsinger, Amy, Lash, Richard H., Redston, Mark, Carter, Scott L., Davison, Jon M., Bass, Adam J.

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Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma von Qie, Shuo, Yoshida, Akihiro, Parnham, Stuart, Oleinik, Natalia, Beeson, Gyda C., Beeson, Craig C., Ogretmen, Besim, Bass, Adam J., Wong, Kwok-Kin, Rustgi, Anil K., Diehl, J. Alan

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Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer? von Goedegebuure, Ruben S A, de Klerk, Leonie K, Bass, Adam J, Derks, Sarah, Thijssen, Victor L J L

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Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer von Zhang, Haisheng, Schaefer, Antje, Wang, Yichen, Hodge, Richard G., Blake, Devon R., Diehl, J. Nathaniel, Papageorge, Alex G., Stachler, Matthew D., Liao, Jennifer, Zhou, Jin, Wu, Zhong, Akarca, Fahire G., de Klerk, Leonie K., Derks, Sarah, Pierobon, Mariaelena, Hoadley, Katherine A., Wang, Timothy C., Church, George, Wong, Kwok-Kin, Petricoin, Emanuel F., Cox, Adrienne D., Lowy, Douglas R., Der, Channing J., Bass, Adam J.

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Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer von Dang, Fabin, Nie, Li, Zhou, Jin, Shimizu, Kouhei, Chu, Chen, Wu, Zhong, Fassl, Anne, Ke, Shizhong, Wang, Yuangao, Zhang, Jinfang, Zhang, Tao, Tu, Zhenbo, Inuzuka, Hiroyuki, Sicinski, Piotr, Bass, Adam J., Wei, Wenyi

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Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis von Chang, Wenju, Wang, Hongshan, Kim, Woosook, Liu, Yang, Deng, Huan, Liu, Haibo, Jiang, Zhengyu, Niu, Zhengchuan, Sheng, Weiwei, Nápoles, Osmel Companioni, Sun, Yihong, Xu, Jianmin, Sepulveda, Antonia, Hayakawa, Yoku, Bass, Adam J., Wang, Timothy C.

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Sox2 Suppresses Gastric Tumorigenesis in Mice von Sarkar, Abby, Huebner, Aaron J., Sulahian, Rita, Anselmo, Anthony, Xu, Xinsen, Flattery, Kyle, Desai, Niyati, Sebastian, Carlos, Yram, Mary Anna, Arnold, Katrin, Rivera, Miguel, Mostoslavsky, Raul, Bronson, Roderick, Bass, Adam J., Sadreyev, Ruslan, Shivdasani, Ramesh A., Hochedlinger, Konrad

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Generation of Genetically Engineered Mouse Lung Organoid Models for Squamous Cell Lung Cancers Allows for the Study of Combinatorial Immunotherapy von Hai, Josephine, Zhang, Hua, Zhou, Jin, Wu, Zhong, Chen, Ting, Papadopoulos, Eleni, Dowling, Catriona M., Pyon, Val, Pan, Yuanwang, Liu, Jie Bin, Bronson, Roderick T., Silver, Heather, Lizotte, Patrick H., Deng, Jiehui, Campbell, Joshua D., Sholl, Lynette M., Ng, Christine, Tsao, Ming-Sound, Thakurdin, Cassandra, Bass, Adam J., Wong, Kwok-Kin

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Profiling critical cancer gene mutations in clinical tumor samples von MacConaill, Laura E, Campbell, Catarina D, Kehoe, Sarah M, Bass, Adam J, Hatton, Charles, Niu, Lili, Davis, Matt, Yao, Keluo, Hanna, Megan, Mondal, Chandrani, Luongo, Lauren, Emery, Caroline M, Baker, Alissa C, Philips, Juliet, Goff, Deborah J, Fiorentino, Michelangelo, Rubin, Mark A, Polyak, Kornelia, Chan, Jennifer, Wang, Yuexiang, Fletcher, Jonathan A, Santagata, Sandro, Corso, Gianni, Roviello, Franco, Shivdasani, Ramesh, Kieran, Mark W, Ligon, Keith L, Stiles, Charles D, Hahn, William C, Meyerson, Matthew L, Garraway, Levi A

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Genomic signatures of past and present chromosomal instability in Barrett’s esophagus and early esophageal adenocarcinoma von Bao, Chunyang, Tourdot, Richard W., Brunette, Gregory J., Stewart, Chip, Sun, Lili, Baba, Hideo, Watanabe, Masayuki, Agoston, Agoston T., Jajoo, Kunal, Davison, Jon M., Nason, Katie S., Getz, Gad, Wang, Kenneth K., Imamura, Yu, Odze, Robert, Bass, Adam J., Stachler, Matthew D., Zhang, Cheng-Zhong

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Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients von Schumacher, Steven E, Shim, Byoung Yong, Corso, Giovanni, Ryu, Min-Hee, Kang, Yoon-Koo, Roviello, Franco, Saksena, Gordon, Peng, Shouyong, Shivdasani, Ramesh A, Bass, Adam J, Beroukhim, Rameen

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RhoA Mutations Identified in Diffuse Gastric Cancer von Zhou, Jin, Hayakawa, Yoku, Wang, Timothy C., Bass, Adam J.

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Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma von Kim, Jihun, Fox, Cameron, Peng, Shouyong, Pusung, Mark, Pectasides, Eirini, Matthee, Eric, Hong, Yong Sang, Do, In-Gu, Jang, Jiryeon, Thorner, Aaron R, Van Hummelen, Paul, Rustgi, Anil K, Wong, Kwok-Kin, Zhou, Zhongren, Tang, Ping, Kim, Kyoung-Mee, Lee, Jeeyun, Bass, Adam J

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