Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension von Zhang, Shan-Shan, Larrabee, Lance, Chang, Andrew H., Desai, Sapna, Sloan, Lisa, Wang, Xin, Wu, Yixuan, Parvez, Nazia, Amaratunga, Karen, Hartman, Allison C., Whitnall, Abby, Mason, Joseph, Barton, Nicholas P., Chu, Audrey Y., Davitte, Jonathan M., Csakai, Adam J., Tibbetts, Caitlin Vestal, Tolbert, Audrey E., O’Keefe, Heather, Polanco, Jessie, Foley, Joseph, Kmett, Casey, Kehler, Jonathan, Kozejova, Gabriela, Wang, Feng, Mayer, Andrew P., Koenig, Patrick, Foletti, Davide, Pitts, Steven J., Schnackenberg, Christine G.

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Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy von Viney, Jonathan M, Andrew, David P, Phillips, Rhian M, Meiser, Andrea, Patel, Pallavi, Lennartz-Walker, Melissa, Cousins, David J, Barton, Nicholas P, Hall, David A, Pease, James E

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Synthesis and Structure–Activity Relationships of Indazole Arylsulfonamides as Allosteric CC-Chemokine Receptor 4 (CCR4) Antagonists von Procopiou, Panayiotis A, Barrett, John W, Barton, Nicholas P, Begg, Malcolm, Clapham, David, Copley, Royston C. B, Ford, Alison J, Graves, Rebecca H, Hall, David A, Hancock, Ashley P, Hill, Alan P, Hobbs, Heather, Hodgson, Simon T, Jumeaux, Coline, Lacroix, Yannick M. L, Miah, Afjal H, Morriss, Karen M. L, Needham, Deborah, Sheriff, Emma B, Slack, Robert J, Smith, Claire E, Sollis, Steven L, Staton, Hugo

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Discovery and optimization of highly ligand-efficient oxytocin receptor antagonists using structure-based drug design von Bellenie, Benjamin R., Barton, Nicholas P., Emmons, Amanda J., Heer, Jag P., Salvagno, Cristian

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Discovery and optimisation of a potent and selective tertiary sulfonamide oxytocin antagonist von Barton, Nicholas P., Bellenie, Benjamin R., Doran, Andrew T., Emmons, Amanda J., Heer, Jag P., Salvagno, Cristian M.

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Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti von Schmidt, Tom L, Barton, Nicholas H, Rašić, Gordana, Turley, Andrew P, Montgomery, Brian L, Iturbe-Ormaetxe, Inaki, Cook, Peter E, Ryan, Peter A, Ritchie, Scott A, Hoffmann, Ary A, O'Neill, Scott L, Turelli, Michael

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Visual dependency and dizziness after vestibular neuritis von Cousins, Sian, Cutfield, Nicholas J, Kaski, Diego, Palla, Antonella, Seemungal, Barry M, Golding, John F, Staab, Jeffrey P, Bronstein, Adolfo M

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Docetaxel and prednisone with or without lenalidomide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (MAINSAIL): a randomised, double-blind, pl... von Petrylak, Daniel P, Prof, Vogelzang, Nicholas J, MD, Budnik, Nikolay, MD, Wiechno, Pawel Jan, MD, Sternberg, Cora N, Prof, Doner, Kevin, MD, Bellmunt, Joaquim, MD, Burke, John M, MD, de Olza, Maria Ochoa, MD, Choudhury, Ananya, PhD, Gschwend, Juergen E, Prof, Kopyltsov, Evgeny, MD, Flechon, Aude, MD, Van As, Nicolas, MD, Houede, Nadine, MD, Barton, Debora, MD, Fandi, Abderrahim, MD, Jungnelius, Ulf, MD, Li, Shaoyi, PhD, de Wit, Ronald, Prof, Fizazi, Karim, Prof

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Randomized Trial of Genotype-Guided Versus Standard Warfarin Dosing in Patients Initiating Oral Anticoagulation von ANDERSON, Jeffrey L, HORNE, Benjamin D, CARLQUIST, John F, STEVENS, Scott M, GROVE, Amanda S, BARTON, Stephanie, NICHOLAS, Zachery P, KAHN, Samera F. S, MAY, Heidi T, SAMUELSON, Kent M, MUHLESTEIN, Joseph B

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Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19 von Horby, Peter, Mafham, Marion, Linsell, Louise, Bell, Jennifer L., Staplin, Natalie, Emberson, Jonathan R., Wiselka, Martin, Ustianowski, Andrew, Elmahi, Einas, Prudon, Benjamin, Whitehouse, Tony, Felton, Timothy, Williams, John, Faccenda, Jakki, Underwood, Jonathan, Baillie, J. Kenneth, Chappell, Lucy C., Faust, Saul N., Jaki, Thomas, Jeffery, Katie, Lim, Wei Shen, Montgomery, Alan, Rowan, Kathryn, Tarning, Joel, Watson, James A., White, Nicholas J., Juszczak, Edmund, Haynes, Richard, Landray, Martin J.

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The contribution of statistical physics to evolutionary biology von de Vladar, Harold P., Barton, Nicholas H.

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Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations von Mayhew, David, Devos, Nathalie, Lambert, Christophe, Brown, James R, Clarke, Stuart C, Kim, Viktoriya L, Magid-Slav, Michal, Miller, Bruce E, Ostridge, Kristoffer K, Patel, Ruchi, Sathe, Ganesh, Simola, Daniel F, Staples, Karl J, Sung, Ruby, Tal-Singer, Ruth, Tuck, Andrew C, Van Horn, Stephanie, Weynants, Vincent, Williams, Nicholas P, Devaster, Jeanne-Marie, Wilkinson, Tom M A

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Phenotypic properties of transmitted founder HIV-1 von Parrish, Nicholas F., Gao, Feng, Li, Hui, Giorgi, Elena E., Barbian, Hannah J., Parrish, Erica H., Zajic, Lara, Iyer, Shilpa S., Decker, Julie M., Kumar, Amit, Hora, Bhavna, Berg, Anna, Cai, Fangping, Hopper, Jennifer, Denny, Thomas N., Ding, Haitao, Ochsenbauer, Christina, Kappes, John C., Galimidi, Rachel P., West, Anthony P., Bjorkman, Pamela J., Wilen, Craig B., Doms, Robert W., O'Brien, Meagan, Bhardwaj, Nina, Borrow, Persephone, Haynes, Barton F., Muldoon, Mark, Theiler, James P., Korber, Bette, Shaw, George M., Hahn, Beatrice H.

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Dynamic maximum entropy provides accurate approximation of structured population dynamics von Bod'ová, Katarína, Szép, Enikő, Barton, Nicholas H

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B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota von Kreuk, Lieselotte Sm, Koch, Meghan A, Slayden, Leianna C, Lind, Nicholas A, Chu, Sophia, Savage, Hannah P, Kantor, Aaron B, Baumgarth, Nicole, Barton, Gregory M

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CRISPR-based herd immunity can limit phage epidemics in bacterial populations von Payne, Pavel, Geyrhofer, Lukas, Barton, Nicholas H, Bollback, Jonathan P

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It's about time: A multistate semicontinuous time mark–recapture model to evaluate seasonal survival and movement rates of juvenile Coho Salmon in a small coastal watershed von Van Vleet, Nicholas P., Ward, Darren M., Som, Nicholas A., Barton, Daniel C., Anderson, Colin, Henderson, Mark J.

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Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals von Whiffin, Nicola, Karczewski, Konrad J., Zhang, Xiaolei, Chothani, Sonia, Smith, Miriam J., Evans, D. Gareth, Roberts, Angharad M., Quaife, Nicholas M., Schafer, Sebastian, Rackham, Owen, Alföldi, Jessica, O’Donnell-Luria, Anne H., Francioli, Laurent C., Cook, Stuart A., Barton, Paul J. R., MacArthur, Daniel G., Ware, James S.

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Non-coding region variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms von Wright, Caroline F., Quaife, Nicholas M., Ramos-Hernández, Laura, Danecek, Petr, Ferla, Matteo P., Samocha, Kaitlin E., Kaplanis, Joanna, Gardner, Eugene J., Eberhardt, Ruth Y., Chao, Katherine R., Karczewski, Konrad J., Morales, Joannella, Gallone, Giuseppe, Balasubramanian, Meena, Banka, Siddharth, Gompertz, Lianne, Kerr, Bronwyn, Kirby, Amelia, Lynch, Sally A., Morton, Jenny E.V., Pinz, Hailey, Sansbury, Francis H., Stewart, Helen, Zuccarelli, Britton D., Cook, Stuart A., Taylor, Jenny C., Juusola, Jane, Retterer, Kyle, Firth, Helen V., Hurles, Matthew E., Lara-Pezzi, Enrique, Barton, Paul J.R., Whiffin, Nicola

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An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice von Castro, João Pl, Yancoskie, Michelle N, Marchini, Marta, Belohlavy, Stefanie, Hiramatsu, Layla, Kučka, Marek, Beluch, William H, Naumann, Ronald, Skuplik, Isabella, Cobb, John, Barton, Nicholas H, Rolian, Campbell, Chan, Yingguang Frank

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