Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy von Cartier, Nathalie, Hacein-Bey-Abina, Salima, Bartholomae, Cynthia C, Veres, Gabor, Schmidt, Manfred, Kutschera, Ina, Vidaud, Michel, Abel, Ulrich, Dal-Cortivo, Liliane, Caccavelli, Laure, Mahlaoui, Nizar, Kiermer, Véronique, Mittelstaedt, Denice, Bellesme, Céline, Lahlou, Najiba, Lefrère, François, Blanche, Stéphane, Audit, Muriel, Payen, Emmanuel, Leboulch, Philippe, l'Homme, Bruno, Bougnères, Pierre, Von Kalle, Christof, Fischer, Alain, Cavazzana-Calvo, Marina, Aubourg, Patrick

Volltext

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy von Montini, Eugenio, Cesana, Daniela, Schmidt, Manfred, Sanvito, Francesca, Bartholomae, Cynthia C, Ranzani, Marco, Benedicenti, Fabrizio, Sergi, Lucia Sergi, Ambrosi, Alessandro, Ponzoni, Maurilio, Doglioni, Claudio, Di Serio, Clelia, von Kalle, Christof, Naldini, Luigi

Volltext

Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer von Weischenfeldt, Joachim, Simon, Ronald, Feuerbach, Lars, Schlangen, Karin, Weichenhan, Dieter, Minner, Sarah, Wuttig, Daniela, Warnatz, Hans-Jörg, Stehr, Henning, Rausch, Tobias, Jäger, Natalie, Gu, Lei, Bogatyrova, Olga, Stütz, Adrian M., Claus, Rainer, Eils, Jürgen, Eils, Roland, Gerhäuser, Clarissa, Huang, Po-Hsien, Hutter, Barbara, Kabbe, Rolf, Lawerenz, Christian, Radomski, Sylwester, Bartholomae, Cynthia C., Fälth, Maria, Gade, Stephan, Schmidt, Manfred, Amschler, Nina, Haß, Thomas, Galal, Rami, Gjoni, Jovisa, Kuner, Ruprecht, Baer, Constance, Masser, Sawinee, von Kalle, Christof, Zichner, Thomas, Benes, Vladimir, Raeder, Benjamin, Mader, Malte, Amstislavskiy, Vyacheslav, Avci, Meryem, Lehrach, Hans, Parkhomchuk, Dmitri, Sultan, Marc, Burkhardt, Lia, Graefen, Markus, Huland, Hartwig, Kluth, Martina, Krohn, Antje, Sirma, Hüseyin, Stumm, Laura, Steurer, Stefan, Grupp, Katharina, Sültmann, Holger, Sauter, Guido, Plass, Christoph, Brors, Benedikt, Yaspo, Marie-Laure, Korbel, Jan O., Schlomm, Thorsten

Volltext

Comprehensive genomic access to vector integration in clinical gene therapy von Arens, Anne, Naldini, Luigi, Cattoglio, Claudia, Eckenberg, Ralph, Deichmann, Annette, Bartholomae, Cynthia C, Faber, Katrin, Nowrouzi, Ali, Paruzynski, Anna, Montini, Eugenio, Thrasher, Adrian J, Ali, Robin R, Saurin, William, Kirsten, Romy, Schwarzwaelder, Kerstin, Schmidt, Manfred, Balaggan, Kamaljit S, Glimm, Hanno, Gaspar, H Bobby, Cesana, Daniela, Biasco, Luca, Aiuti, Alessandro, Howe, Steven J, Recchia, Alessandra, Gabriel, Richard, Cohen-Haguenauer, Odile, Wang, Wei, Mavilio, Fulvio, Yáñez-Muñoz, Rafael J, von Kalle, Christof, Ball, Claudia R

Volltext

Propagation and origin of warm anomalies in the Angola Benguela upwelling system in 2001 von Rouault, M., Illig, S., Bartholomae, C, Reason, C.J.C., Bentamy, A.

Volltext

Analyzing the number of common integration sites of viral vectors--new methods and computer programs von Abel, Ulrich, Deichmann, Annette, Nowrouzi, Ali, Gabriel, Richard, Bartholomae, Cynthia C, Glimm, Hanno, von Kalle, Christof, Schmidt, Manfred

Volltext

Effects of environmental variables on survey catch rates and distribution by size of shallow‐ and deep‐water Cape hakes, Merluccius capensis and Merluccius paradoxus off Namibia... von Kainge, P., Plas, A. K., Bartholomae, C. H., Wieland, K.

Volltext

Self-inactivating MLV vectors have a reduced genotoxic profile in human epidermal keratinocytes von Cavazza, A, Cocchiarella, F, Bartholomae, C, Schmidt, M, Pincelli, C, Larcher, F, Mavilio, F

Volltext

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition von Kool, Marcel, Jones, David T.W., Jäger, Natalie, Northcott, Paul A., Pugh, Trevor J., Hovestadt, Volker, Piro, Rosario M., Esparza, L. Adriana, Markant, Shirley L., Remke, Marc, Milde, Till, Bourdeaut, Franck, Ryzhova, Marina, Sturm, Dominik, Pfaff, Elke, Stark, Sebastian, Hutter, Sonja, Şeker-Cin, Huriye, Johann, Pascal, Bender, Sebastian, Schmidt, Christin, Rausch, Tobias, Shih, David, Reimand, Jüri, Sieber, Laura, Wittmann, Andrea, Linke, Linda, Witt, Hendrik, Weber, Ursula D., Zapatka, Marc, König, Rainer, Beroukhim, Rameen, Bergthold, Guillaume, van Sluis, Peter, Volckmann, Richard, Koster, Jan, Versteeg, Rogier, Schmidt, Sabine, Wolf, Stephan, Lawerenz, Chris, Bartholomae, Cynthia C., von Kalle, Christof, Unterberg, Andreas, Herold-Mende, Christel, Hofer, Silvia, Kulozik, Andreas E., von Deimling, Andreas, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Hasselblatt, Martin, Crawford, John R., Grant, Gerald A., Jabado, Nada, Perry, Arie, Cowdrey, Cynthia, Croul, Sydney, Zadeh, Gelareh, Korbel, Jan O., Doz, Francois, Delattre, Olivier, Bader, Gary D., McCabe, Martin G., Collins, V. Peter, Kieran, Mark W., Cho, Yoon-Jae, Pomeroy, Scott L., Witt, Olaf, Brors, Benedikt, Taylor, Michael D., Schüller, Ulrich, Korshunov, Andrey, Eils, Roland, Wechsler-Reya, Robert J., Lichter, Peter, Pfister, Stefan M.

Volltext

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma von Jones, David T W, Hutter, Barbara, Jäger, Natalie, Korshunov, Andrey, Kool, Marcel, Warnatz, Hans-Jörg, Zichner, Thomas, Lambert, Sally R, Ryzhova, Marina, Quang, Dong Anh Khuong, Fontebasso, Adam M, Stütz, Adrian M, Hutter, Sonja, Zuckermann, Marc, Sturm, Dominik, Gronych, Jan, Lasitschka, Bärbel, Schmidt, Sabine, Şeker-Cin, Huriye, Witt, Hendrik, Sultan, Marc, Ralser, Meryem, Northcott, Paul A, Hovestadt, Volker, Bender, Sebastian, Pfaff, Elke, Stark, Sebastian, Faury, Damien, Schwartzentruber, Jeremy, Majewski, Jacek, Weber, Ursula D, Zapatka, Marc, Raeder, Benjamin, Schlesner, Matthias, Worth, Catherine L, Bartholomae, Cynthia C, von Kalle, Christof, Imbusch, Charles D, Radomski, Sylwester, Lawerenz, Chris, van Sluis, Peter, Koster, Jan, Volckmann, Richard, Versteeg, Rogier, Lehrach, Hans, Monoranu, Camelia, Winkler, Beate, Unterberg, Andreas, Herold-Mende, Christel, Milde, Till, Kulozik, Andreas E, Ebinger, Martin, Schuhmann, Martin U, Cho, Yoon-Jae, Pomeroy, Scott L, von Deimling, Andreas, Witt, Olaf, Taylor, Michael D, Wolf, Stephan, Karajannis, Matthias A, Eberhart, Charles G, Scheurlen, Wolfram, Hasselblatt, Martin, Ligon, Keith L, Kieran, Mark W, Korbel, Jan O, Yaspo, Marie-Laure, Brors, Benedikt, Felsberg, Jörg, Reifenberger, Guido, Collins, V Peter, Jabado, Nada, Eils, Roland, Lichter, Peter

Volltext

Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency von Abdul-Razak, H. H., Rocca, C. J., Howe, S. J., Alonso-Ferrero, M. E., Wang, J., Gabriel, R., Bartholomae, C. C., Gan, C. H. V., Garín, M. I., Roberts, A., Blundell, M. P., Prakash, V., Molina-Estevez, F. J., Pantoglou, J., Guenechea, G., Holmes, M. C., Gregory, P. D., Kinnon, C., von Kalle, C., Schmidt, M., Bueren, J. A., Thrasher, A. J., Yáñez-Muñoz, R. J.

Volltext

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing von Hovestadt, Volker, Jones, David T. W., Picelli, Simone, Wang, Wei, Kool, Marcel, Northcott, Paul A., Sultan, Marc, Stachurski, Katharina, Ryzhova, Marina, Warnatz, Hans-Jörg, Ralser, Meryem, Brun, Sonja, Bunt, Jens, Jäger, Natalie, Kleinheinz, Kortine, Erkek, Serap, Weber, Ursula D., Bartholomae, Cynthia C., von Kalle, Christof, Lawerenz, Chris, Eils, Jürgen, Koster, Jan, Versteeg, Rogier, Milde, Till, Witt, Olaf, Schmidt, Sabine, Wolf, Stephan, Pietsch, Torsten, Rutkowski, Stefan, Scheurlen, Wolfram, Taylor, Michael D., Brors, Benedikt, Felsberg, Jörg, Reifenberger, Guido, Borkhardt, Arndt, Lehrach, Hans, Wechsler-Reya, Robert J., Eils, Roland, Yaspo, Marie-Laure, Landgraf, Pablo, Korshunov, Andrey, Zapatka, Marc, Radlwimmer, Bernhard, Pfister, Stefan M., Lichter, Peter

Volltext

Retroviral Vector Performance in Defined Chromosomal Loci of Modular Packaging Cell Lines von GAMA-NORTON, L, HERRMANN, S, HAUSER, H, WIRTH, D, SCHUCHT, R, COROADINHA, A. S, LÖW, R, ALVES, P. M, BARTHOLOMAE, C. C, SCHMIDT, M, BAUM, C, SCHAMBACH, A

Volltext

The seasonal variability of the northern Benguela undercurrent and its relation to the oxygen budget on the shelf von Mohrholz, V., Bartholomae, C.H., van der Plas, A.K., Lass, H.U.

Volltext

Stem Cell Gene Therapy for Fanconi Anemia: Report from the 1st International Fanconi Anemia Gene Therapy Working Group Meeting von Tolar, Jakub, Adair, Jennifer E, Antoniou, Michael, Bartholomae, Cynthia C, Becker, Pamela S, Blazar, Bruce R, Bueren, Juan, Carroll, Thomas, Cavazzana-Calvo, Marina, Clapp, D Wade, Dalgleish, Robert, Galy, Anne, Gaspar, H Bobby, Hanenberg, Helmut, Von Kalle, Christof, Kiem, Hans-Peter, Lindeman, Dirk, Naldini, Luigi, Navarro, Susana, Renella, Raffaele, Rio, Paula, Sevilla, Julián, Schmidt, Manfred, Verhoeyen, Els, Wagner, John E, Williams, David A, Thrasher, Adrian J

Volltext

Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing von Schmidt, Manfred, Paruzynski, Anna, Arens, Anne, Gabriel, Richard, Bartholomae, Cynthia C, Scholz, Simone, Wang, Wei, Wolf, Stephan, Glimm, Hanno, von Kalle, Christof

Volltext

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection von Biffi, Alessandra, Bartolomae, Cynthia C., Cesana, Daniela, Cartier, Natalie, Aubourg, Patrik, Ranzani, Marco, Cesani, Martina, Benedicenti, Fabrizio, Plati, Tiziana, Rubagotti, Enrico, Merella, Stefania, Capotondo, Alessia, Sgualdino, Jacopo, Zanetti, Gianluigi, von Kalle, Christof, Schmidt, Manfred, Naldini, Luigi, Montini, Eugenio

Volltext

Overexpression of the anti-apoptotic protein AVEN contributes to increased malignancy in hematopoietic neoplasms von Eißmann, M, Melzer, I M, Fernández, S B M, Michel, G, Hrabě de Angelis, M, Hoefler, G, Finkenwirth, P, Jauch, A, Schoell, B, Grez, M, Schmidt, M, Bartholomae, C C, Newrzela, S, Haetscher, N, Rieger, M A, Zachskorn, C, Mittelbronn, M, Zörnig, M

Volltext

Lentiviral Hematopoietic Cell Gene Therapy for X-Linked Adrenoleukodystrophy von Cartier, Nathalie, Hacein-Bey-Abina, Salima, Bartholomae, Cynthia C., Bougnères, Pierre, Schmidt, Manfred, Von Kalle, Christof, Fischer, Alain, Cavazzana-Calvo, Marina, Aubourg, Patrick

Volltext

Lentiviral vector–based insertional mutagenesis identifies genes associated with liver cancer von Ranzani, Marco, Cesana, Daniela, Bartholomae, Cynthia C, Sanvito, Francesca, Pala, Mauro, Benedicenti, Fabrizio, Gallina, Pierangela, Sergi, Lucia Sergi, Merella, Stefania, Bulfone, Alessandro, Doglioni, Claudio, von Kalle, Christof, Kim, Yoon Jun, Schmidt, Manfred, Tonon, Giovanni, Naldini, Luigi, Montini, Eugenio

Volltext