Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates von Dong, Yizhou, Love, Kevin T., Dorkin, J. Robert, Sirirungruang, Sasilada, Zhang, Yunlong, Chen, Delai, Bogorad, Roman L., Yin, Hao, Chen, Yi, Vegas, Arturo J., Alabi, Christopher A., Sahay, Gaurav, Olejnik, Karsten T., Wang, Weiheng, Schroeder, Avi, Lytton-Jean, Abigail K. R., Siegwart, Daniel J., Akinc, Akin, Barnes, Carmen, Barros, Scott A., Carioto, Mary, Fitzgerald, Kevin, Hettinger, Julia, Kumar, Varun, Novobrantseva, Tatiana I., Qin, June, Querbes, William, Koteliansky, Victor, Langer, Robert, Anderson, Daniel G.

Volltext

Rational design of cationic lipids for siRNA delivery von Semple, Sean C, Akinc, Akin, Chen, Jianxin, Sandhu, Ammen P, Mui, Barbara L, Cho, Connie K, Sah, Dinah W Y, Stebbing, Derrick, Crosley, Erin J, Yaworski, Ed, Hafez, Ismail M, Dorkin, J Robert, Qin, June, Lam, Kieu, Rajeev, Kallanthottathil G, Wong, Kim F, Jeffs, Lloyd B, Nechev, Lubomir, Eisenhardt, Merete L, Jayaraman, Muthusamy, Kazem, Mikameh, Maier, Martin A, Srinivasulu, Masuna, Weinstein, Michael J, Chen, Qingmin, Alvarez, Rene, Barros, Scott A, De, Soma, Klimuk, Sandra K, Borland, Todd, Kosovrasti, Verbena, Cantley, William L, Tam, Ying K, Manoharan, Muthiah, Ciufolini, Marco A, Tracy, Mark A, de Fougerolles, Antonin, MacLachlan, Ian, Cullis, Pieter R, Madden, Thomas D, Hope, Michael J

Volltext

Shielding of Lipid Nanoparticles for siRNA Delivery: Impact on Physicochemical Properties, Cytokine Induction, and Efficacy von Kumar, Varun, Qin, June, Jiang, Yongfeng, Duncan, Richard G, Brigham, Benjamin, Fishman, Shannon, Nair, Jayaprakash K, Akinc, Akin, Barros, Scott A, Kasperkovitz, Pia V

Volltext

OSWG Recommendations for Genotoxicity Testing of Novel Oligonucleotide-Based Therapeutics von Berman, Cindy L., Barros, Scott A., Galloway, Sheila M., Kasper, Peter, Oleson, Frederick B., Priestley, Catherine C., Sweder, Kevin S., Schlosser, Michael J., Sobol, Zhanna

Volltext

Safety profile of RNAi nanomedicines von Barros, Scott A., Gollob, Jared A.

Volltext

Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalNAc-siRNA conjugates von Janas, Maja M, Zlatev, Ivan, Liu, Ju, Jiang, Yongfeng, Barros, Scott A, Sutherland, Jessica E, Davis, Wendell P, Liu, Jingxuan, Brown, Christopher R, Liu, Xiumin, Schlegel, Mark K, Blair, Lauren, Zhang, Xuemei, Das, Biplab, Tran, Chris, Aluri, Krishna, Li, Jing, Agarwal, Saket, Indrakanti, Ramesh, Charisse, Klaus, Nair, Jayaprakash, Matsuda, Shigeo, Rajeev, Kallanthottathil G, Zimmermann, Tracy, Sepp-Lorenzino, Laura, Xu, Yuanxin, Akinc, Akin, Fitzgerald, Kevin, Vaishnaw, Akshay K, Smith, Peter F, Manoharan, Muthiah, Jadhav, Vasant, Wu, Jing-Tao, Maier, Martin A

Volltext

Impact of Oligonucleotide Structure, Chemistry, and Delivery Method on In Vitro Cytotoxicity von Janas, Maja M., Jiang, Yongfeng, Schlegel, Mark K., Waldron, Scott, Kuchimanchi, Satya, Barros, Scott A.

Volltext

Exposure to siRNA-GalNAc Conjugates in Systems of the Standard Test Battery for Genotoxicity von Janas, Maja M., Jiang, Yongfeng, Duncan, Richard G., Hayes, Antoinette N., Liu, Ju, Kasperkovitz, Pia V., Placke, Michael E., Barros, Scott A.

Volltext

Molecular structure and characterization of a novel murine ABC transporter, Abca13 von Barros, Scott A, Tennant, Raymond W, Cannon, Ronald E

Volltext

Safety profile of RNAi nanomedicines: Nanotoxicity: From Bench to Bedside von BARROS, Scott A, GOLLOB, Jared A

Volltext

Activation of Protein Kinase Cζ Increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated Transport von Barros, Scott A., Srimaroeng, Chutima, Perry, Jennifer L., Walden, Ramsey, Dembla-Rajpal, Neetu, Sweet, Douglas H., Pritchard, John B.

Volltext

Expanded Therapeutic Index Of Antithrombin Silencing and Correction Of Aptt In a Hemophilia A Mouse Model von Barros, Scott A, Carioto, Mary, Hettinger, Julia, Jiang, Yongfeng, Qin, June, Prabhala, Harsha, Sehgal, Alfica, Akinc, Akin

Volltext

Activation of Protein Kinase Cζ Increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated Transport von Scott A. Barros, Chutima Srimaroeng, Jennifer L. Perry, Ramsey Walden, Neetu Dembla-Rajpal, Douglas H. Sweet, John B. Pritchard

Volltext

Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport von Barros, Scott A, Srimaroeng, Chutima, Perry, Jennifer L, Walden, Ramsey, Dembla-Rajpal, Neetu, Sweet, Douglas H, Pritchard, John B

Volltext

Predictive Toxicogenomics in Preclinical Discovery von Barros, Scott A., Martin, Rory B.

Volltext

Hydraulic traits explain differential responses of Amazonian forests to the 2015 El Niño-induced drought von de V. Barros, Fernanda, Bittencourt, Paulo R. L., Brum, Mauro, Restrepo-Coupe, Natalia, Pereira, Luciano, Teodoro, Grazielle S., Saleska, Scott R., Borma, Laura S., Christoffersen, Bradley O., Penha, Deliane, Alves, Luciana F., Lima, Adriano J. N., Carneiro, Vilany M. C., Gentine, Pierre, Lee, Jung-Eun, Aragão, Luiz E. O. C., Ivanov, Valeriy, Leal, Leila S. M., Araujo, Alessandro C., Oliveira, Rafael S.

Volltext

Think Tanks, Business and Civil Society: The Ethics of Promoting Pro-corporate Ideologies von Barros, Amon, Taylor, Scott

Volltext

The tethered peptide activation mechanism of adhesion GPCRs von Barros-Álvarez, Ximena, Nwokonko, Robert M., Vizurraga, Alexander, Matzov, Donna, He, Feng, Papasergi-Scott, Makaía M., Robertson, Michael J., Panova, Ouliana, Yardeni, Eliane Hadas, Seven, Alpay B., Kwarcinski, Frank E., Su, Hongyu, Peroto, Maria Claudia, Meyerowitz, Justin G., Shalev-Benami, Moran, Tall, Gregory G., Skiniotis, Georgios

Volltext

Parenting in the Context of Deportation Risk von Berger Cardoso, Jodi, Scott, Jennifer L., Faulkner, Monica, Barros Lane, Liza

Volltext

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs von Akinc, Akin, Maier, Martin A., Manoharan, Muthiah, Fitzgerald, Kevin, Jayaraman, Muthusamy, Barros, Scott, Ansell, Steven, Du, Xinyao, Hope, Michael J., Madden, Thomas D., Mui, Barbara L., Semple, Sean C., Tam, Ying K., Ciufolini, Marco, Witzigmann, Dominik, Kulkarni, Jayesh A., van der Meel, Roy, Cullis, Pieter R.

Volltext