Questions and answers from IRI's members von Goss, Will, Kashdan, David, Miller, Bill, Johnson, Albert, Janda, Bruce W, Rekart, Ted, Baron, Ray

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Questions and Answers From IRI's Members: What are IRI members talking about? These questions were recently posed on IRI's Community Forum von Helmick, Dave, Goss, Will, Kashdan, David, Seth, Jyoti, Miller, Bill, Johnson, Albert, Repinec, Steve, Janda, Bruce W., Rekart, Ted, Baron, Ray, Johnson, Albert

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PRODUCTO ALIMENTICIO TIPO BARRA MASTICABLE von DALE SLESSER, JOHN M. KAISER, ROBART BARON, RAY GREEN

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Lenvatinib plus Pembrolizumab for Advanced Endometrial Cancer von Makker, Vicky, Colombo, Nicoletta, Casado Herráez, Antonio, Santin, Alessandro D, Colomba, Emeline, Miller, David S, Fujiwara, Keiichi, Pignata, Sandro, Baron-Hay, Sally, Ray-Coquard, Isabelle, Shapira-Frommer, Ronnie, Ushijima, Kimio, Sakata, Jun, Yonemori, Kan, Kim, Yong Man, Guerra, Eva M, Sanli, Ulus A, McCormack, Mary M, Smith, Alan D, Keefe, Stephen, Bird, Steven, Dutta, Lea, Orlowski, Robert J, Lorusso, Domenica

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Metabolomic derangements are associated with mortality in critically ill adult patients von Rogers, Angela J, McGeachie, Michael, Baron, Rebecca M, Gazourian, Lee, Haspel, Jeffrey A, Nakahira, Kiichi, Fredenburgh, Laura E, Hunninghake, Gary M, Raby, Benjamin A, Matthay, Michael A, Otero, Ronny M, Fowler, Vance G, Rivers, Emanuel P, Woods, Christopher W, Kingsmore, Stephen, Langley, Ray J, Choi, Augustine M K

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Identifying Water–Anion Correlated Motion in Aqueous Solutions through Van Hove Functions von Shinohara, Yuya, Matsumoto, Ray, Thompson, Matthew W, Ryu, Chae Woo, Dmowski, Wojciech, Iwashita, Takuya, Ishikawa, Daisuke, Baron, Alfred Q. R, Cummings, Peter T, Egami, Takeshi

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BAMBI elimination enhances alternative TGF-β signaling and glomerular dysfunction in diabetic mice von Fan, Ying, Li, Xuezhu, Xiao, Wenzhen, Fu, Jia, Harris, Ray C, Lindenmeyer, Maja, Cohen, Clemens D, Guillot, Nicolas, Baron, Margaret H, Wang, Niansong, Lee, Kyung, He, John C, Schlondorff, Detlef, Chuang, Peter Y

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Health-Related Quality of Life in Patients With Advanced Endometrial Cancer Treated With Lenvatinib Plus Pembrolizumab or Treatment of Physician’s Choice von Lorusso, Domenica, Colombo, Nicoletta, Herraez, Antonio Casado, Santin, Alessandro D., Colomba, Emeline, Miller, David Scott, Fujiwara, Keiichi, Pignata, Sandro, Baron-Hay, Sally E., Ray-Coquard, Isabelle Laure, Shapira-Frommer, Ronnie, Kim, Yong Man, McCormack, Mary, Massaad, Rachid, Nguyen, Allison Martin, Zhao, Qi, McKenzie, Jodi, Prabhu, Vimalanand S., Makker, Vicky

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Breast-Cancer Adjuvant Therapy with Zoledronic Acid von Coleman, Robert E, Marshall, Helen, Cameron, David, Dodwell, David, Burkinshaw, Roger, Keane, Maccon, Gil, Miguel, Houston, Stephen J, Grieve, Robert J, Barrett-Lee, Peter J, Ritchie, Diana, Pugh, Julia, Gaunt, Claire, Rea, Una, Peterson, Jennifer, Davies, Claire, Hiley, Victoria, Gregory, Walter, Bell, Richard

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Lenvatinib Plus Pembrolizumab in Previously Treated Advanced Endometrial Cancer: Updated Efficacy and Safety From the Randomized Phase III Study 309/KEYNOTE-775 von Makker, Vicky, Colombo, Nicoletta, Casado Herráez, Antonio, Monk, Bradley J, Mackay, Helen, Santin, Alessandro D, Miller, David S, Moore, Richard G, Baron-Hay, Sally, Ray-Coquard, Isabelle, Ushijima, Kimio, Yonemori, Kan, Kim, Yong Man, Guerra Alia, Eva M, Sanli, Ulus A, Bird, Steven, Orlowski, Robert, McKenzie, Jodi, Okpara, Chinyere, Barresi, Gianmaria, Lorusso, Domenica

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Reliability of a novel classification system for thoracolumbar injuries: the Thoracolumbar Injury Severity Score von Vaccaro, Alexander R, Baron, Eli M, Sanfilippo, James, Jacoby, Sidney, Steuve, Jacob, Grossman, Eric, DiPaola, Matthew, Ranier, Paul, Austin, Luke, Ropiak, Ray, Ciminello, Michael, Okafor, Chuka, Eichenbaum, Matthew, Rapuri, Venkat, Smith, Eric, Orozco, Fabio, Ugolini, Peter, Fletcher, Mark, Minnich, Jonathan, Goldberg, Gregory, Wilsey, Jared, Lee, Joon Y, Lim, Moe R, Burns, Anthony, Marino, Ralph, DiPaola, Christian, Zeiller, Laura, Zeiler, Steven C, Harrop, James, Anderson, D Greg, Albert, Todd J, Hilibrand, Alan S

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Antibiotics as first-line alternative to appendicectomy in adult appendicitis: 90-day follow-up from a prospective, multicentre cohort study von Javanmard-Emamghissi, H., Hollyman, M., Boyd-Carson, H., Doleman, B., Adiamah, A., Lund, J. N., Moler-Zapata, S., Grieve, R., Moug, S. J., Tierney, G. M.

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525MO Updated efficacy and safety of lenvatinib (LEN) + pembrolizumab (pembro) vs treatment of physician’s choice (TPC) in patients (pts) with advanced endometrial cancer (aEC): St... von Makker, V., Colombo, N., Casado Herraez, A., Monk, B.J., Mackay, H., Santin, A.D., Miller, D.S., Moore, R.G., Baron-Hay, S.E., Ray-Coquard, I.L., Shapira-Frommer, R., Ushijima, K., Yonemori, K., Kim, Y.M., Guerra Alia, E.M., Sanli, U.A., Huang, J., McKenzie, J., Barresi, G., Lorusso, D.

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Transferability of health cost evaluation across locations in oncology: cluster and principal component analysis as an explorative tool von Perrier, Lionel, Buja, Alessandra, Mastrangelo, Giuseppe, Baron, Patrick Sylvestre, Ducimetière, Françoise, Pauwels, Petrus J, Rossi, Carlo Riccardo, Gilly, François Noël, Martin, Amaury, Favier, Bertrand, Farsi, Fadila, Laramas, Mathieu, Baldo, Vincenzo, Collard, Olivier, Cellier, Dominic, Blay, Jean-Yves, Ray-Coquard, Isabelle

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20MO Time to deterioration in quality of life in patients (pts) with advanced endometrial cancer (aEC) treated with lenvatinib plus pembrolizumab (L+P) or treatment of physician’s... von Lorusso, D., Colombo, N., Casado Herraez, A., Santin, A.D., Colomba, E., Miller, D.S., Fujiwara, K., Pignata, S., Baron-Hay, S.E., Ray-Coquard, I.L., Shapira-Frommer, R., Kim, Y.M., McCormack, M., Massaad, R., Martin Nguyen, A., Zhao, Q., McKenzie, J., Prabhu, V.S., Makker, V.

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Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] P... von Abbate, Antonio, MD, PhD, Kontos, Michael C., MD, Grizzard, John D., MD, Biondi-Zoccai, Giuseppe G.L., MD, Van Tassell, Benjamin W., PharmD, Robati, Roshanak, MD, Roach, Lenore M., RN, Arena, Ross A., PhD, Roberts, Charlotte S., ACNP, Varma, Amit, MD, Gelwix, Christopher C., MD, Salloum, Fadi N., PhD, Hastillo, Andrea, MD, Dinarello, Charles A., MD, Vetrovec, George W., MD

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Health-related quality of life (HRQoL) in advanced endometrial cancer (aEC) patients (pts) treated with lenvatinib plus pembrolizumab or treatment of physician’s choice (TPC) von Lorusso, Domenica, Colombo, Nicoletta, Casado Herraez, Antonio, Santin, Alessandro, Colomba, Emeline, Miller, David Scott, Fujiwara, Keiichi, Pignata, Sandro, Baron-Hay, Sally E., Ray-Coquard, Isabelle Laure, Shapira-Frommer, Ronnie, Kim, Yong Man, McCormack, Mary, Bird, Steven, Prabhu, Vimalanand S., Martin Nguyen, Allison, Zhao, Qi, Dutta, Lea, Makker, Vicky

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A multicenter, open-label, randomized, phase III study to compare the efficacy and safety of lenvatinib in combination with pembrolizumab versus treatment of physician's choice in... von Makker, Vicky, Colombo, Nicoletta, Herráez, Antonio Casado, Santin, Alessandro, Colomba, Emeline, Miller, David, Fujiwara, Keiichi, Pignata, Sandro, Baron-Hay, Sally, Ray-Coquard, Isabelle, Shapira-Frommer, Ronnie, Ushijima, Kimio, Sakata, Jun, Yonemori, Kan, Kim, Yong Man, Guerra, Eva, Sanli, Ulus, McCormack, Mary, Huang, Jie, Smith, Alan, Keefe, Stephen, Dutta, Lea, Orlowski, Robert, Lorusso, Domenica

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Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients von Hodge, Rebecca, Mandle, Hannah B, Ray, Stephen, Tandon, Sonia, Peterson, Meaghan, Henry, Abigail, Jahan, Ferdous A, Bostick, Roberd M, Baron, John A, Barry, Elizabeth L, Yacoub, Rami, Rutherford, Robin E, Seabrook, March E, Fedirko, Veronika

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Assessing the performance of indicators during their life cycle: the mixed QUID method von Michel, Philippe, Fraticelli, Laurie, Parneix, Pierre, Daucourt, Valentin, Farges, Olivier, Gasquet, Isabelle, Occelli, Pauline, Ray-Coquard, Isabelle, Duclos, Antoine

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