Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion von Singh, Mandeep S., Balmer, Jasmin, Barnard, Alun R., Aslam, Sher A., Moralli, Daniela, Green, Catherine M., Barnea-Cramer, Alona, Duncan, Isabel, MacLaren, Robert E.

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Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial von MacLaren, Robert E, Prof, Groppe, Markus, PhD, Barnard, Alun R, PhD, Cottriall, Charles L, PhD, Tolmachova, Tanya, PhD, Seymour, Len, Prof, Clark, K Reed, PhD, During, Matthew J, Prof, Cremers, Frans P M, Prof, Black, Graeme C M, Prof, Lotery, Andrew J, Prof, Downes, Susan M, FRCOphth, Webster, Andrew R, Prof, Seabra, Miguel C, Prof

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Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization von Charbel Issa, Peter, Alun R. Barnard, Philipp Herrmann, Ilyas Washington, Robert E. MacLaren

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Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia von Xue, Kanmin, Jolly, Jasleen K, Barnard, Alun R., Rudenko, Anna, Salvetti, Anna P., Patrício, Maria I., Edwards, Thomas L., Groppe, Markus, Orlans, Harry O., Tolmachova, Tanya, Black, Graeme C., Webster, Andrew R., Lotery, Andrew J., Holder, Graham E., Downes, Susan M., Seabra, Miguel C., MacLaren, Robert E.

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Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation von Singh, Mandeep S., Issa, Peter Charbel, Butler, Rachel, Martin, Chris, Lipinski, Daniel M., Sekaran, Sumathi, Barnard, Alun R., MacLaren, Robert E.

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Visual Acuity after Retinal Gene Therapy for Choroideremia von Edwards, Thomas L, Jolly, Jasleen K, Groppe, Markus, Barnard, Alun R, Cottriall, Charles L, Tolmachova, Tanya, Black, Graeme C, Webster, Andrew R, Lotery, Andrew J, Holder, Graham E, Xue, Kanmin, Downes, Susan M, Simunovic, Matthew P, Seabra, Miguel C, MacLaren, Robert E

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Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice von Barnea-Cramer, Alona O., Wang, Wei, Lu, Shi-Jiang, Singh, Mandeep S., Luo, Chenmei, Huo, Hongguang, McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Lanza, Robert

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Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa von Orlans, Harry O., McClements, Michelle E., Barnard, Alun R., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E.

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RNA Editing as a Therapeutic Approach for Retinal Gene Therapy Requiring Long Coding Sequences von Fry, Lewis E., Peddle, Caroline F., Barnard, Alun R., McClements, Michelle E., MacLaren, Robert E.

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Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy von De Silva, Samantha R., Barnard, Alun R., Hughes, Steven, Tam, Shu K. E., Martin, Chris, Singh, Mandeep S., Barnea-Cramer, Alona O., McClements, Michelle E., During, Matthew J., Peirson, Stuart N., Hankins, Mark W., MacLaren, Robert E.

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When clocks go bad: neurobehavioural consequences of disrupted circadian timing von Barnard, Alun R, Nolan, Patrick M

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Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy von Chandler, Laurel C., Yusuf, Imran H., McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Xue, Kanmin

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Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision von Altimus, Cara M, Zhao, Haiqing, Badea, Tudor C, Yau, King-Wai, Ecker, Jennifer L, Barnard, Alun R, Lall, Gurprit S, Hankins, Mark W, Berson, David M, Haq, Shafiqul, Lucas, Robert J, Güler, Ali D, Hattar, Samer, Liao, Hsi-Wen, Cahill, Hugh

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Repair of Retinal Degeneration following Ex Vivo Minicircle DNA Gene Therapy and Transplantation of Corrected Photoreceptor Progenitors von Barnea-Cramer, Alona O., Singh, Mandeep, Fischer, Dominik, De Silva, Samantha, McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E.

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The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification von Cross, Sally H., Mckie, Lisa, Hurd, Toby W., Riley, Sam, Wills, Jimi, Barnard, Alun R., Young, Fiona, MacLaren, Robert E., Jackson, Ian J.

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CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa von Lipinski, Daniel M, Barnard, Alun R, Singh, Mandeep S, Martin, Chris, Lee, Edward J, Davies, Wayne I L, MacLaren, Robert E

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Filtration of Short-Wavelength Light Provides Therapeutic Benefit in Retinitis Pigmentosa Caused by a Common Rhodopsin Mutation von Orlans, Harry O, Merrill, Jonathon, Barnard, Alun R, Charbel Issa, Peter, Peirson, Stuart N, MacLaren, Robert E

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After-Hours Mutant Reveals a Role for Fbxl3 in Determining Mammalian Circadian Period von Godinho, Sofia I.H, Maywood, Elizabeth S, Shaw, Linda, Tucci, Valter, Barnard, Alun R, Busino, Luca, Pagano, Michele, Kendall, Rachel, Quwailid, Mohamed M, Romero, M. Rosario, O'Neill, John, Chesham, Johanna E, Brooker, Debra, Lalanne, Zuzanna, Hastings, Michael H, Nolan, Patrick M

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Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo von Tolmachova, Tanya, Tolmachov, Oleg E., Barnard, Alun R., de Silva, Samantha R., Lipinski, Daniel M., Walker, Nathan J., MacLaren, Robert E., Seabra, Miguel C.

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Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina von Patrício, Maria I., Barnard, Alun R., Orlans, Harry O., McClements, Michelle E., MacLaren, Robert E.

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