Abstract 335: Efficacy of FGFR inhibitors and combination therapies for acquired resistance in FGFR2-fusion cholangiocarcinoma von Krook, Melanie A., Lenyo, Alexandria M., Wilberding, Maxwell J., Barker, Hannah D., Dantuono, Mikayla, Chen, Hui-Zi, Reeser, Julie W., Wing, Michele R., Miya, Jharna, Samorodnitsky, Eric, Smith, Amy M., Dao, Thuy, Martin, Dorrelyn M., Dittmar, Kristin, Ciombor, Kristen K., Hays, John L., Freud, Aharon G., Roychowdhury, Sameek

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A transient apical extracellular matrix relays cytoskeletal patterns to shape permanent acellular ridges on the surface of adult C. elegans von Katz, Sophie S, Barker, Trevor J, Maul-Newby, Hannah M, Sparacio, Alessandro P, Nguyen, Ken C Q, Maybrun, Chloe L, Belfi, Alexandra, Cohen, Jennifer D, Hall, David H, Sundaram, Meera V, Frand, Alison R

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Less-structured time in children's daily lives predicts self-directed executive functioning von Barker, Jane E, Semenov, Andrei D, Michaelson, Laura, Provan, Lindsay S, Snyder, Hannah R, Munakata, Yuko

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Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation von Alangari, Abdullah A., Ashoori, Matin D., Alwan, Wisam, Dawe, Hannah R., Stockinger, Brigitta, Barker, Jonathan N., Wincent, Emma, Di Meglio, Paola

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Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial von Folegatti, Pedro M, Bibi, Sagida, Chappell, Harry, Fedosyuk, Sofiya, Gbesemete, Diane, Kelly, Elizabeth J, Makinson, Rebecca, Rawlinson, Thomas, Ross-Russell, Amy L, Saich, Stephen, Smith, Catherine C, Tarrant, Richard, Thomas, Kelly M, Warren, Sarah C, Lambe, Teresa, Adams, Kelly, Ali, Aabidah, Allen, Lauren, Baker, Natalie, Barrett, Kelly, Bellamy, Duncan, Berg, Adam, Beveridge, Amy, Bewley, Kevin, Bijker, Else M., Boland, Elena, Bormans, Daan, Bower, Thomas, Boyd, Amy, Brenner, Tanja, Buttigieg, Karen R., Cao, Michelangelo, Chapman, David, Chelysheva, Irina, Cifuentes, Liliana, Collins, Sarah, Conlon, Christopher P., Davis, Judith, Dong, Tao, Drake, Jonathan, Fisher, Richard, Garlant, Harriet, Gavrila, Madita, Gibbons, Felicity, Gill, Hardeep, Hart, Thomas C., Hartnell, Birgit, Haskell, Louise, Hawkins, Sophia, Hermosin Herrera, Macarena, Hill, David, Hill, Jennifer, Howes, Jessica, Jackson, Susan, Joshi, Amar, Kelly, Dearbhla M., King, Lloyd D.W., Knott, Daniel, Lee, Kim Y.N., Leung, Stephanie, Liu, Shuchang, Loew, Lisa, Madhavan, Meera, Marius, Phedra, Marshall, Julia L., Martin, Jane, Moore, Maria, Morris, Susan J., O'Reilly, Peter John, Owino, Nelly, Patel, Bhumika, Patrick-Smith, Maia, Perring, James, Phillips, Daniel J., Poulton, Ian, Presland, Laura, Pulido, David, Rajapaska, Durga, Ramos Lopez, Fernando, Rollier, Christine S., Romani, Rossana, Sedik, Cynthia, Seddiqi, Samiullah, Segireddy, Rameswara R., Sharpe, Hannah R., Silva-Reyes, Laura, Smith, David J., Smith, Daniel C., Smith, Nicholas, Stockley, David, Summerton, Eloise, Szigeti, Anna, Taylor, Ursula, Tonks, Susan, Tree, Julian A., Truby, Adam, Varughese, Rachel, Woodyer, Mark, Worth, Andrew T., Yao, Xin Li

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RNA velocity of single cells von La Manno, Gioele, Soldatov, Ruslan, Zeisel, Amit, Braun, Emelie, Hochgerner, Hannah, Petukhov, Viktor, Lidschreiber, Katja, Kastriti, Maria E., Lönnerberg, Peter, Furlan, Alessandro, Fan, Jean, Borm, Lars E., Liu, Zehua, van Bruggen, David, Guo, Jimin, He, Xiaoling, Barker, Roger, Sundström, Erik, Castelo-Branco, Gonçalo, Cramer, Patrick, Adameyko, Igor, Linnarsson, Sten, Kharchenko, Peter V.

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Slow slip along the Hikurangi margin linked to fluid-rich sediments trailing subducting seamounts von Bangs, Nathan L., Morgan, Julia K., Bell, Rebecca E., Han, Shuoshuo, Arai, Ryuta, Kodaira, Shuichi, Gase, Andrew C., Wu, Xinming, Davy, Richard, Frahm, Laura, Tilley, Hannah L., Barker, Daniel H. N., Edwards, Joel H., Tobin, Harold J., Reston, Tim J., Henrys, Stuart A., Moore, Gregory F., Bassett, Dan, Kellett, Richard, Stucker, Valerie, Fry, Bill

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High-quality health systems in the Sustainable Development Goals era: time for a revolution von Kruk, Margaret E, Gage, Anna D, Arsenault, Catherine, Jordan, Keely, Leslie, Hannah H, Roder-DeWan, Sanam, Adeyi, Olusoji, Barker, Pierre, Daelmans, Bernadette, Doubova, Svetlana V, English, Mike, García-Elorrio, Ezequiel, Guanais, Frederico, Gureje, Oye, Hirschhorn, Lisa R, Jiang, Lixin, Kelley, Edward, Lemango, Ephrem Tekle, Liljestrand, Jerker, Malata, Address, Marchant, Tanya, Matsoso, Malebona Precious, Meara, John G, Mohanan, Manoj, Ndiaye, Youssoupha, Norheim, Ole F, Reddy, K Srinath, Rowe, Alexander K, Salomon, Joshua A, Thapa, Gagan, Twum-Danso, Nana A Y, Pate, Muhammad

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Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, ran... von Aley, Parvinder K, Harndahl, Linda, Haughney, John, Hicks, Alexander, Lambe, Teresa, Moore, Patrick, Mughal, Mehmood, Mujadidi, Yama F, Pan, Daniel, Regan, Karen, Saich, Stephen, Salkeld, Jo, Sheridan, Ray, Sturdy, Ann, Todd, Shirley, Read, Robert C, Nguyen-Van-Tam, Jonathan S, Rogers, Chris A, Longshaw, Laura, Reeder, Sally, Storton, Kim, Tandy, Bridget, Cox, Stephen, Shenoy, Anil, Calderwood, James, Thorp, Helen, Evans, Julie, Thorpe, Jeanette, Batham, Sally, Hailstone, Jessica, Phillips, Rachael, Makia, Fiona, Hopkins, NinaSimone, khan, Farida, Adebambo, Olumide, Chita, Sunder, Mazzella, Andrea, Jackson, Beth, Broadhead, Samantha, Hale, Colin, Gibney, Jennifer, Stackpoole, Michael, Lyon, Rebecca, Cole, Christine, Beckett, Helen, Brown, Claire, Trinham, Charlotte, Hurdover, Steve, Ferreira Da Silva, Carla, White, Rachel, Morshead, Gertraud, Kasanyinga, Mwila, Clutterbuck, Elizabeth A., Bibi, Sagida, Stuart, Arabella SV, Shaw, Robert H, Galvin, Dominic, Patel, Gita, Mouland, Johanna, Longhurst, Beverley, Moon, Maria, Giddins, Beth, Minnis, Christine, Buttigieg, Karren, Knight, Chanice, Brown, Phillip, Shaik, Imam, Allen, Lauren, Thomas, Steve, Perkins, Jonathan, Gowland, Andrew, Peters, Erica, James, Rob, Seath, Ingrid, Newman, Joseph, Boubriak, Iryna, Bell, Judith, Coughlan, Tricia, Ronan, Nicholas, Dare, Tracey, Ricamara, Marivic, Roy, Subarna, Ambihapathy, Wythehi, Spencer, Joanne, Warren, Sarah, Haskell, Louise, Romani, Rossana, Bentley, Ian, Watson, Tara, Nightingale, Kari, Lingwood, Aidan, Chalwin, Olivia, Burton, Holly, Welham, Benjamin, Branney, Debbie, Wiselka, Martin, Vail, Dennyl, Lewis-Taylor, Jessica, Magan, Javier, Appleby, Kim

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Breaking antimicrobial resistance by disrupting extracytoplasmic protein folding von Furniss, R Christopher D, Kaderabkova, Nikol, Barker, Declan, Bernal, Patricia, Maslova, Evgenia, Antwi, Amanda A A, McNeil, Helen E, Pugh, Hannah L, Dortet, Laurent, Blair, Jessica M A, Larrouy-Maumus, Gerald, McCarthy, Ronan R, Gonzalez, Diego, Mavridou, Despoina A I

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Effects of Maternal Sensitivity and Cognitive and Linguistic Stimulation on Cochlear Implant Users' Language Development over Four Years von Quittner, Alexandra L., PhD, Cruz, Ivette, PhD, Barker, David H., PhD, Tobey, Emily, PhD, Eisenberg, Laurie S., PhD, Niparko, John K., MD

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Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation von O'Boyle, Graeme, Fox, Christopher R. J, Walden, Hannah R, Willet, Joseph D. P, Mavin, Emily R, Hine, Dominic W, Palmer, Jeremy M, Barker, Catriona E, Lamb, Christopher A, Ali, Simi, Kirby, John A

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A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study von Page, Elizabeth C, Brook, Mark N, McHugh, Jana, Jones, Ann-Britt, Merson, Susan, Ong, Kai Ren, Hoffman, Jonathan, Huber, Camilla, Grindedal, Eli Marie, Stormorken, Astrid, Hanson, Helen, James, Paul, Syngal, Sapna, Barwell, Julian, Teixeira, Manuel R, Macrae, Finlay A, Pachter, Nicholas, Buys, Saundra, Cooney, Kathleen A, Taylor, Amy, Hogben, Matthew, Castro, Elena, Dearnaley, David, Dias, Alexander, Dudderidge, Tim, Hamdy, Freddie C, Mikropoulos, Christos, Mitra, Anita V, Moynihan, Clare, Rennert, Gad, Collier, Rebecca, Adlard, Julian, Alfonso, Rosa, Ball, Darran, Benton, Barbara, Biller, Leah, Burgess, Lucy, Callard, Alice, Carter, Vanda, Catanzaro, Mario, Compton, Cecilia, Cornford, Philip, Costello, Philandra, Coulier, Laura, Douglas, Fiona, Douglas, Emma, Ellery, Natalie, Frydenberg, Mark, Fuller, Debbie, Gabriel, Camila, Genova, Elena, George, Angela, Georgiou, Demetra, Goff, Sally, Goldgar, David, Goodman, Selina, Gray, Catherine, Griffiths, Julie, Gupwell, Karin, Hart, Rachel, Hawkes, Lara, Hilario, Kathrine, Hulick, Peter, Jenkins, Sharon, Josefsberg Ben-Yehoshua, Sagi, Kinsella, Netty, Kumar, Pardeep, Leibovici, Dan, Martin, Phoebe, Murphy, Morgan, Mzazi, Shumi, Nadolski, Maria, Park, Linda, Patel, Nafisa, Paulo Souto, João, Peixoto, Ana, Petelin, Lara, Poile, Charlotte, Purnell, Helen, Rankin, Brigette, Renton, Caroline, Sajoo, Anaar, Saunders, Kathryn, Searle, Anne, Sehra, Ravinder, Shackleton, Kylie, Shaw, Adam, Shevrin, Daniel, Siguake, Kas, Snadden, Lesley, Sorrentino, Margherita, Thomas, Maggie, Townshend, Sharron, Tricker, Karen, Tripathi, Vishakha, Valdagni, Riccardo, Verdon, Lizzie, Vogel, Kristen, Watford, Amy, Offman, Judith

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Early Readmissions after Acute Myocardial Infarction von Kwok, Chun Shing, MBBS MSc BSc, Wong, Chun Wai, Shufflebotham, Hannah, MBChB, Brindley, Luke, MB ChB, Fatima, Tamseel, MBBS, Shufflebotham, Adrian, Barker, Diane, MBChB MD, Patwala, Ashish, MBChB MD, Heatlie, Grant, MBBS PhD, Mamas, Mamas A, BMBCh DPhil

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“Everything hurts!” Distress in semantic variant primary progressive aphasia von Barker, Megan S., Silverman, Hannah E., Fremont, Rachel, Manoochehri, Masood, Cosentino, Stephanie, Huey, Edward D.

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The Relationship Between Dietary Patterns, Cognition, and Cardiometabolic Health in Healthy, Older Adults von Simpson, Felicity M, Wade, Alexandra, Stanford, Ty, Mellow, Maddison L, Collins, Clare E, Murphy, Karen J, Keage, Hannah A D, Hunter, Montana, Ware, Nicholas, Barker, Daniel, Smith, Ashleigh E, Karayanidis, Frini

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Longitudinal change in ultrasound-derived rectus femoris cross-sectional area in COPD von Jenkins, Timothy O, Patel, Suhani, Edwards, George D, Nolan, Claire M, Canavan, Jane, Kon, Samantha, Jones, Sarah, Barker, Ruth E, Littlemore, Hannah, Maddocks, Matthew, Man, William D-C

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1,2,4-Triazolo-[1,5‑a]pyridine HIF Prolylhydroxylase Domain‑1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction von Ahmed, Saleh, Ayscough, Andrew, Barker, Greg R, Canning, Hannah E, Davenport, Richard, Downham, Robert, Harrison, David, Jenkins, Kerry, Kinsella, Natasha, Livermore, David G, Wright, Susanne, Ivetac, Anthony D, Skene, Robert, Wilkens, Steven J, Webster, Natalie A, Hendrick, Alan G

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Prevalence of depression and anxiety symptoms after stroke in young adults: A systematic review and meta-analysis von Ignacio, Katrina Hannah D., Muir, Ryan T., Diestro, Jose Danilo B., Singh, Nishita, Yu, Melody Hope Lim Lee, Omari, Omar El, Abdalrahman, Rana, Barker-Collo, Suzanne L., Hackett, Maree L., Dukelow, Sean P., Almekhlafi, Mohammed A.

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The contribution of behavioral features to caregiver burden in FTLD spectrum disorders von Silverman, Hannah E., Ake, Jeannie M., Manoochehri, Masood, Appleby, Brian S., Brushaber, Danielle, Devick, Katrina L., Dickerson, Bradford C., Fields, Julie A., Forsberg, Leah K., Ghoshal, Nupur, Graff‐Radford, Neill R., Grossman, Murray, Heuer, Hilary W., Kornak, John, Lapid, Maria I., Litvan, Irene, Mackenzie, Ian R., Mendez, Mario F., Onyike, Chiadi U., Pascual, Belen, Tartaglia, Maria Carmela, Boeve, Bradley F., Boxer, Adam L., Rosen, Howard J., Cosentino, Stephanie, Huey, Edward D., Barker, Megan S., Goldman, Jill S.

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