A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study von Witkowski, Benoit, PhD, Duru, Valentine, MSc, Khim, Nimol, PhD, Ross, Leila S, PhD, Saintpierre, Benjamin, MSc, Beghain, Johann, MSc, Chy, Sophy, BS, Kim, Saorin, BS, Ke, Sopheakvatey, BS, Kloeung, Nimol, BS, Eam, Rotha, BS, Khean, Chanra, BS, Ken, Malen, BS, Loch, Kaknika, BS, Bouillon, Anthony, PhD, Domergue, Anais, MSc, Ma, Laurence, MSc, Bouchier, Christiane, PhD, Leang, Rithea, PhD, Huy, Rekol, MD, Nuel, Grégory, Prof, Barale, Jean-Christophe, PhD, Legrand, Eric, PhD, Ringwald, Pascal, MD, Fidock, David A, Prof, Mercereau-Puijalon, Odile, PhD, Ariey, Frédéric, PhD, Ménard, Didier, Dr

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A molecular marker of artemisinin-resistant Plasmodium falciparum malaria von Ariey, Frédéric, Witkowski, Benoit, Amaratunga, Chanaki, Beghain, Johann, Langlois, Anne-Claire, Khim, Nimol, Kim, Saorin, Duru, Valentine, Bouchier, Christiane, Ma, Laurence, Lim, Pharath, Leang, Rithea, Duong, Socheat, Sreng, Sokunthea, Suon, Seila, Chuor, Char Meng, Bout, Denis Mey, Ménard, Sandie, Rogers, William O., Genton, Blaise, Fandeur, Thierry, Miotto, Olivo, Ringwald, Pascal, Le Bras, Jacques, Berry, Antoine, Barale, Jean-Christophe, Fairhurst, Rick M., Benoit-Vical, Françoise, Mercereau-Puijalon, Odile, Ménard, Didier

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Reduced Artemisinin Susceptibility of Plasmodium falciparum Ring Stages in Western Cambodia von WITKOWSKI, Benoit, KHIM, Nimol, DONDORP, Arjen M, TRIPURA, Rupam, BENOIT-VICAL, Françoise, BERRY, Antoine, GORGETTE, Olivier, ARIEY, Frédéric, BARALE, Jean-Christophe, MERCEREAU-PUIJALON, Odile, MENARD, Didier, CHIM, Pheaktra, KIM, Saorin, KE, Sopheakvatey, KLOEUNG, Nimol, CHY, Sophy, DUONG, Socheat, LEANG, Rithea, RINGWALD, Pascal

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Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress von Martinez, Mariano, Bouillon, Anthony, Brûlé, Sébastien, Raynal, Bertrand, Haouz, Ahmed, Alzari, Pedro M, Barale, Jean-Christophe

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Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites von Bougdour, Alexandre, Maubon, Danièle, Baldacci, Patricia, Ortet, Philippe, Bastien, Olivier, Bouillon, Anthony, Barale, Jean-Christophe, Pelloux, Hervé, Ménard, Robert, Hakimi, Mohamed-Ali

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Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target von Wagner, Matthias Paulus, Formaglio, Pauline, Gorgette, Olivier, Dziekan, Jerzy Michal, Huon, Christèle, Berneburg, Isabell, Rahlfs, Stefan, Barale, Jean-Christophe, Feinstein, Sheldon I., Fisher, Aron B., Ménard, Didier, Bozdech, Zbynek, Amino, Rogerio, Touqui, Lhousseine, Chitnis, Chetan E.

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Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens von Jacob, Daria, Ruffie, Claude, Dubois, Myriam, Combredet, Chantal, Amino, Rogerio, Formaglio, Pauline, Gorgette, Olivier, Pehau-Arnaudet, Gérard, Guery, Charline, Puijalon, Odile, Barale, Jean-Christophe, Ménard, Robert, Tangy, Frédéric, Sala, Monica

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Computational design of protein-based inhibitors of Plasmodium vivax subtilisin-like 1 protease von Bastianelli, Giacomo, Bouillon, Anthony, Nguyen, Christophe, Le-Nguyen, Dung, Nilges, Michael, Barale, Jean-Christophe

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A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms von Ménard, Didier, Khim, Nimol, Beghain, Johann, Adegnika, Ayola A, Shafiul-Alam, Mohammad, Amodu, Olukemi, Rahim-Awab, Ghulam, Barnadas, Céline, Berry, Antoine, Boum, Yap, Bustos, Maria D, Cao, Jun, Chen, Jun-Hu, Collet, Louis, Cui, Liwang, Thakur, Garib-Das, Dieye, Alioune, Djallé, Djibrine, Dorkenoo, Monique A, Eboumbou-Moukoko, Carole E, Espino, Fe-Esperanza-Caridad J, Fandeur, Thierry, Ferreira-da-Cruz, Maria-Fatima, Fola, Abebe A, Fuehrer, Hans-Peter, Hassan, Abdillahi M, Herrera, Socrates, Hongvanthong, Bouasy, Houzé, Sandrine, Ibrahim, Maman L, Jahirul-Karim, Mohammad, Jiang, Lubin, Kano, Shigeyuki, Ali-Khan, Wasif, Khanthavong, Maniphone, Kremsner, Peter G, Lacerda, Marcus, Leang, Rithea, Leelawong, Mindy, Li, Mei, Lin, Khin, Mazarati, Jean-Baptiste, Ménard, Sandie, Morlais, Isabelle, Muhindo-Mavoko, Hypolite, Musset, Lise, Na-Bangchang, Kesara, Nambozi, Michael, Niaré, Karamoko, Noedl, Harald, Ouédraogo, Jean-Bosco, Pillai, Dylan R, Pradines, Bruno, Quang-Phuc, Bui, Ramharter, Michael, Randrianarivelojosia, Milijaona, Sattabongkot, Jetsumon, Sheikh-Omar, Abdiqani, Silué, Kigbafori D, Sirima, Sodiomon B, Sutherland, Colin, Syafruddin, Din, Tahar, Rachida, Tang, Lin-Hua, Touré, Offianan A, Tshibangu-wa-Tshibangu, Patrick, Vigan-Womas, Inès, Warsame, Marian, Wini, Lyndes, Zakeri, Sedigheh, Kim, Saorin, Eam, Rotha, Berne, Laura, Khean, Chanra, Chy, Sophy, Ken, Malen, Loch, Kaknika, Canier, Lydie, Duru, Valentine, Legrand, Eric, Barale, Jean-Christophe, Stokes, Barbara, Straimer, Judith, Witkowski, Benoit, Fidock, David A, Rogier, Christophe, Ringwald, Pascal, Ariey, Frederic, Mercereau-Puijalon, Odile

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Computational reverse-engineering of a spider-venom derived peptide active against Plasmodium falciparum SUB1 von Bastianelli, Giacomo, Bouillon, Anthony, Nguyen, Christophe, Crublet, Elodie, Pêtres, Stéphane, Gorgette, Olivier, Le-Nguyen, Dung, Barale, Jean-Christophe, Nilges, Michael

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Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity von Chamond, Nathalie, Goytia, Maira, Coatnoan, Nicolas, Barale, Jean‐Christophe, Cosson, Alain, Degrave, Wim M., Minoprio, Paola

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3D structures of the Plasmodium vivax subtilisin‐like drug target SUB1 reveal conformational changes to accommodate a substrate‐derived α‐ketoamide inhibitor von Martinez, Mariano, Batista, Fernando A., Maurel, Manon, Bouillon, Anthony, Ortega Varga, Laura, Wehenkel, Anne Marie, Le Chevalier-Sontag, Lucile, Blondel, Arnaud, Haouz, Ahmed, Hernandez, Jean-François, Alzari, Pedro M., Barale, Jean-Christophe

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Mammalian Subtilisin/Kexin Isozyme SKI-1: A Widely Expressed Proprotein Convertase with a Unique Cleavage Specificity and Cellular Localization von Seidah, Nabil G., Mowla, Seyed J., Hamelin, Josee, Mamarbachi, Aida M., Benjannet, Suzanne, Toure, Barry B., Basak, Ajoy, Munzer, Jon Scott, Marcinkiewicz, Jadwiga, Zhong, Mei, Barale, Jean-Christophe, Lazure, Claude, Murphy, Richard A., Chretien, Michel, Marcinkiewicz, Mieczyslaw

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Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1 von Legru, Alice, Batista, Fernando A., Puszko, Anna K., Bouillon, Anthony, Maurel, Manon, Martinez, Mariano, Ejjoummany, Abdelaziz, Ortega Varga, Laura, Adler, Pauline, Méchaly, Ariel, Hadjadj, Margot, Sosnowski, Piotr, Hopfgartner, Gérard, Alzari, Pedro M., Blondel, Arnaud, Haouz, Ahmed, Barale, Jean-Christophe, Hernandez, Jean-François

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Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia von Mairet-Khedim, Mélissa, Roesch, Camille, Khim, Nimol, Srun, Sreynet, Bouillon, Anthony, Kim, Saorin, Ke, Sopheakvatey, Kauy, Chhayleang, Kloeung, Nimol, Eam, Rotha, Khean, Chanra, Kul, Chanvong, Chy, Sophy, Leang, Rithea, Ringwald, Pascal, Barale, Jean-Christophe, Witkowski, Benoit

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Plasmodium falciparum Subtilisin-Like Protease 2, a Merozoite Candidate for the Merozoite Surface Protein 1-42 Maturase von Barale, Jean-Christophe, Blisnick, Thierry, Fujioka, Hisashi, Alzari, Pedro M., Aikawa, Masamishi, Braun-Breton, Catherine, Langsley, Gordon

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In Silico Screening on the Three-dimensional Model of the Plasmodium vivax SUB1 Protease Leads to the Validation of a Novel Anti-parasite Compound von Bouillon, Anthony, Giganti, David, Benedet, Christophe, Gorgette, Olivier, Pêtres, Stéphane, Crublet, Elodie, Girard-Blanc, Christine, Witkowski, Benoit, Ménard, Didier, Nilges, Michael, Mercereau-Puijalon, Odile, Stoven, Véronique, Barale, Jean-Christophe

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A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity von Moine, Espérance, Denevault-Sabourin, Caroline, Debierre-Grockiego, Françoise, Silpa, Laurence, Gorgette, Olivier, Barale, Jean-Christophe, Jacquiet, Philippe, Brossier, Fabien, Gueiffier, Alain, Dimier-Poisson, Isabelle, Enguehard-Gueiffier, Cécile

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Gene targeting demonstrates that the Plasmodium berghei subtilisin PbSUB2 is essential for red cell invasion and reveals spontaneous genetic recombination events von Uzureau, Pierrick, Barale, Jean‐Christophe, Janse, Chris J., Waters, Andrew P., Breton, Catherine Braun

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CyProQuant-PCR: a real time RT-PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical use von Boeuf, Philippe, Vigan-Womas, Inès, Jublot, Delphine, Loizon, Séverine, Barale, Jean-Christophe, Akanmori, Bartholomew Dicky, Mercereau-Puijalon, Odile, Behr, Charlotte

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