Tolerogenic form of Factor VIII to prevent inhibitor development in the treatment of Hemophilia A von Nguyen, Nhan H., Dingman, Robert K., Balu‐Iyer, Sathy V.

Volltext

Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis von Bankert, Richard B, Balu-Iyer, Sathy V, Odunsi, Kunle, Shultz, Leonard D, Kelleher, Jr, Raymond J, Barnas, Jennifer L, Simpson-Abelson, Michelle, Parsons, Robert, Yokota, Sandra J

Volltext

The Effect of Small Oligomeric Protein Aggregates on the Immunogenicity of Intravenous and Subcutaneous Administered Antibodies von Fathallah, Anas M., Chiang, Manting, Mishra, Anshul, Kumar, Sandeep, Xue, Li, Russell Middaugh, C., Balu-Iyer, Sathy V.

Volltext

Rational design of a nanoparticle platform for oral prophylactic immunotherapy to prevent immunogenicity of therapeutic proteins von Nguyen, Nhan H., Glassman, Fiona Y., Dingman, Robert K., Shenoy, Gautam N., Wohlfert, Elizabeth A., Kay, Jason G., Bankert, Richard B., Balu-Iyer, Sathy V.

Volltext

Delivery of Therapeutic Proteins von Pisal, Dipak S., Kosloski, Matthew P., Balu-Iyer, Sathy V.

Volltext

Immune regulatory adjuvant approach to mitigate subcutaneous immunogenicity of monoclonal antibodies von Jarvi, Nicole L, Patel, Manali, Shetty, Krithika A, Nguyen, Nhan H, Grasperge, Brooke F, Mager, Donald E, Straubinger, Robert M, Balu-Iyer, Sathy V

Volltext

Lumefantrine solid dispersions with piperine for the enhancement of solubility, bioavailability and anti-parasite activity von Takale, Nikita R., Aji, Anjali, Jane, Kanchan, Deshmukh, Prasad R., Pendharkar, Vishal V., Khade, Rajendra R., Ghule, Balu V., Inamdar, Nazma N., Kotagale, Nandkishor R.

Volltext

A mechanistic marker-based screening tool to predict clinical immunogenicity of biologics von Jarvi, Nicole L., Balu-Iyer, Sathy V.

Volltext

Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments von Bhatta, Maulasri, Shenoy, Gautam N, Loyall, Jenni L, Gray, Brian D, Bapardekar, Meghana, Conway, Alexis, Minderman, Hans, Kelleher Jr, Raymond J, Carreno, Beatriz M, Linette, Gerald, Shultz, Leonard D, Odunsi, Kunle, Balu-Iyer, Sathy V, Pak, Koon Yan, Bankert, Richard B

Volltext

Native-Like Aggregates of Factor VIII Are Immunogenic in von Willebrand Factor Deficient and Hemophilia a Mice von Pisal, Dipak S., Kosloski, Matthew P., Middaugh, C. Russell, Bankert, Richard B., Balu-iyer, Sathy V.

Volltext

Synthesis and Antibacterial Activity of Novel Amido-Amine-Based Cationic Gemini Surfactants von Ghumare, Anant K., Pawar, Balu V., Bhagwat, Sunil S.

Volltext

Phospholipid binding improves plasma survival of factor VIII von PISAL, Dipak S, BALU-LYER, Sathy V

Volltext

Immunogenicity of Protein Pharmaceuticals von Dingman, Robert, Balu-Iyer, Sathy V.

Volltext

Transition Metal‐Free sp3 C–H Functionalization of Arylacetic Acids for the Synthesis of 1,3,5‐Triazines von Pardeshi, Sachin D., Sathe, Pratima A., Pawar, Balu V., Vadagaonkar, Kamlesh S., Chaskar, Atul C.

Volltext

Preclinical evaluation of cancer immune therapy using patient‐derived tumor antigen‐specific T cells in a novel xenograft platform von Shenoy, Gautam N, Greene, Christopher J, Bhatta, Maulasri, Baroja, Miren L, Loyall, Jenni L, Balu‐Iyer, Sathy V, Kelleher, Raymond J, Carreno, Beatriz M, Linette, Gerald P, Shultz, Leonard D, Bankert, Richard B

Volltext

Subcutaneous Absorption of Monoclonal Antibodies: Role of Dose, Site of Injection, and Injection Volume on Rituximab Pharmacokinetics in Rats von Kagan, Leonid, Turner, Michael R., Balu-Iyer, Sathy V., Mager, Donald E.

Volltext

Anatomical, Physiological, and Experimental Factors Affecting the Bioavailability of sc-Administered Large Biotherapeutics von Fathallah, Anas M., Balu-Iyer, Sathy V.

Volltext

Exposure of FVIII in the Presence of Phosphatidyl Serine Reduces Generation of Memory B-Cells and Induces Regulatory T-Cell-Mediated Hyporesponsiveness in Hemophilia A Mice von Ramakrishnan, Radha, Davidowitz, Andrew, Balu-Iyer, Sathy V.

Volltext

Phosphatidylinositol induces fluid phase formation and packing defects in phosphatidylcholine model membranes von Peng, Aaron, Pisal, Dipak S., Doty, Amy, Balu-Iyer, Sathy V.

Volltext

Immunogenicity Challenges Associated with Subcutaneous Delivery of Therapeutic Proteins von Jarvi, Nicole L., Balu-Iyer, Sathy V.

Volltext