A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development von O’Keefe, Ryan N., Carli, Annalisa L. E., Baloyan, David, Chisanga, David, Shi, Wei, Afshar-Sterle, Shoukat, Eissmann, Moritz F., Poh, Ashleigh R., Pal, Bhupinder, Seillet, Cyril, Locksley, Richard M., Ernst, Matthias, Buchert, Michael

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Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth von Thilakasiri, Pathum, Huynh, Jennifer, Poh, Ashleigh R, Tan, Chin Wee, Nero, Tracy L, Tran, Kelly, Parslow, Adam C, Afshar‐Sterle, Shoukat, Baloyan, David, Hannan, Natalie J, Buchert, Michael, Scott, Andrew Mark, Griffin, Michael DW, Hollande, Frederic, Parker, Michael W, Putoczki, Tracy L, Ernst, Matthias, Chand, Ashwini L

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Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice von Poh, Ashleigh R., Dwyer, Amy R., Eissmann, Moritz F., Chand, Ashwini L., Baloyan, David, Boon, Louis, Murrey, Michael W., Whitehead, Lachlan, O'Brien, Megan, Lowell, Clifford A., Putoczki, Tracy L., Pixley, Fiona J., O'Donoghue, Robert J. J., Ernst, Matthias

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Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer von Johnstone, Cameron N, Pattison, Andrew D, Gorringe, Kylie L, Harrison, Paul F, Powell, David R, Lock, Peter, Baloyan, David, Ernst, M, Stewart, Alastair G, Beilharz, Traude H, Anderson, Robin L

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Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages von Morrow, Riley J, Allam, Amr H, Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F, Jacob, Saumya P, O'Brien, Megan, Poh, Ashleigh R, Ernst, Matthias

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BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking von Tran, Sharon, Juliani, Juliani, Harris, Tiffany J., Evangelista, Marco, Ratcliffe, Julian, Ellis, Sarah L., Baloyan, David, Reehorst, Camilla M., Nightingale, Rebecca, Luk, Ian Y., Jenkins, Laura J., Ghilas, Sonia, Yakou, Marina H., Inguanti, Chantelle, Johnson, Chad, Buchert, Michael, Lee, James C., De Cruz, Peter, Duszyc, Kinga, Gleeson, Paul A., Kile, Benjamin T., Mielke, Lisa A., Yap, Alpha S., Mariadason, John M., Fairlie, W. Douglas, Lee, Erinna F.

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Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis von Poh, Ashleigh R., O’Brien, Megan, Chisanga, David, He, Hong, Baloyan, David, Traichel, Jasmin, Dijkstra, Christine, Chopin, Michaël, Nutt, Stephen, Whitehead, Lachlan, Boon, Louis, Parkin, Ashleigh, Lowell, Clifford, Pajic, Marina, Shi, Wei, Nikfarjam, Mehrdad, Ernst, Matthias

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DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression von Afshar-Sterle, Shoukat, Carli, Annalisa L E, O'Keefe, Ryan, Tse, Janson, Fischer, Stefanie, Azimpour, Alexander I, Baloyan, David, Elias, Lena, Thilakasiri, Pathum, Patel, Onisha, Ferguson, Fleur M, Eissmann, Moritz F, Chand, Ashwini L, Gray, Nathanael S, Busuttil, Rita, Boussioutas, Alex, Lucet, Isabelle S, Ernst, Matthias, Buchert, Michael

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Host IL11 Signaling Suppresses CD4+ T cell-Mediated Antitumor Responses to Colon Cancer in Mice von Huynh, Jennifer, Baloyan, David, Chisanga, David, Shi, Wei, O'Brien, Megan, Afshar-Sterle, Shoukat, Alorro, Mariah, Pang, Lokman, Williams, David S., Parslow, Adam C., Thilakasiri, Pathum, Eissmann, Moritz F., Boon, Louis, Masson, Frederick, Chand, Ashwini L., Ernst, Matthias

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Tumor Growth Remains Refractory to IMyc/I Ablation in Host Macrophages von Morrow, Riley J, Allam, Amr H, Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F, Jacob, Saumya P, O’Brien, Megan, Poh, Ashleigh R, Ernst, Matthias

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Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon-γ-Dependent Manner von Eissmann, Moritz F, Dijkstra, Christine, Wouters, Merridee A, Baloyan, David, Mouradov, Dmitri, Nguyen, Paul M, Davalos-Salas, Mercedes, Putoczki, Tracy L, Sieber, Oliver M, Mariadason, John M, Ernst, Matthias, Masson, Frederick

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Annexin A1 Is Required for Efficient Tumor Initiation and Cancer Stem Cell Maintenance in a Model of Human Breast Cancer von Johnstone, Cameron N., Tu, Yan, Langenbach, Shenna, Baloyan, David, Pattison, Andrew D., Lock, Peter, Britt, Kara L., Lehmann, Brian D., Beilharz, Traude H., Ernst, Matthias, Anderson, Robin L., Stewart, Alastair G.

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The site of breast cancer metastases dictates their clonal composition and reversible transcriptomic profile von Berthelet, Jean, Wimmer, Verena C., Whitfield, Holly J., Serrano, Antonin, Boudier, Thomas, Mangiola, Stefano, Merdas, Michal, El-Saafin, Farrah, Baloyan, David, Wilcox, Jordan, Wilcox, Steven, Parslow, Adam C., Papenfuss, Anthony T., Yeo, Belinda, Ernst, Matthias, Pal, Bhupinder, Anderson, Robin L., Davis, Melissa J., Rogers, Kelly L., Hollande, Frederic, Merino, Delphine

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Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy von Poh, Ashleigh R, Love, Christopher G, Chisanga, David, Steer, James H, Baloyan, David, Chopin, Michaël, Nutt, Stephen, Rautela, Jai, Huntington, Nicholas D, Etemadi, Nima, O'Brien, Megan, O'Keefe, Ryan, Ellies, Lesley G, Macri, Christophe, Mintern, Justine D, Whitehead, Lachlan, Gangadhara, Gangadhara, Boon, Louis, Chand, Ashwini L, Lowell, Clifford A, Shi, Wei, Pixley, Fiona J, Ernst, Matthias

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Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3 von Thilakasiri, Pathum, O'Keefe, Ryan N, To, Sarah Q, Chisanga, David, Eissmann, Moritz F, Carli, Annalisa LE, Duscio, Belinda, Baloyan, David, Dmello, Rhynelle S, Williams, David, Mariadason, John, Poh, Ashleigh R, Pal, Bhupinder, Kile, Benjamin T, Vissers, Joseph Ha, Harvey, Kieran F, Buchert, Michael, Shi, Wei, Ernst, Matthias, Chand, Ashwini L

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