Prediction of Drug Absorption Using Multivariate Statistics von Egan, William J, Merz, Kenneth M, Baldwin, John J

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Allosteric Inhibitors of Inducible Nitric Oxide Synthase Dimerization Discovered via Combinatorial Chemistry von McMillan, Kirk, Adler, Marc, Auld, Douglas S., Baldwin, John J., Blasko, Eric, Browne, Leslie J., Chelsky, Daniel, Davey, David, Dolle, Ronald E., Eagen, Keith A., Erickson, Shawn, Feldman, Richard I., Glaser, Charles B., Mallari, Cornell, Morrissey, Michael M., Michael H. J. Ohlmeyer, Pan, Gonghua, Parkinson, John F., Phillips, Gary B., Polokoff, Mark A., Sigal, Nolan H., Vergona, Ronald, Whitlow, Marc, Young, Tish A., Devlin, James J.

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Application of the Three-Dimensional Structures of Protein Target Molecules in Structure-Based Drug Design von Greer, Jonathan, Erickson, John W, Baldwin, John J, Varney, Michael D

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Drug discovery and development 2014: Returning toward the norm? von Baldwin, John J

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Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists von Chiba, Jun, Takayama, Gensuke, Takashi, Tohru, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Moriarty, Kevin J., Sarko, Christopher R., Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela, Machinaga, Nobuo

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Optimization of orally bioavailable alkyl amine renin inhibitors von Xu, Zhenrong, Cacatian, Salvacion, Yuan, Jing, Simpson, Robert D., Jia, Lanqi, Zhao, Wei, Tice, Colin M., Flaherty, Patrick T., Guo, Joan, Ishchenko, Alexey, Singh, Suresh B., Wu, Zhongren, McKeever, Brian M., Scott, Boyd B., Bukhtiyarov, Yuri, Berbaum, Jennifer, Mason, Jennifer, Panemangalore, Reshma, Cappiello, Maria Grazia, Bentley, Ross, Doe, Christopher P., Harrison, Richard K., McGeehan, Gerard M., Dillard, Lawrence W., Baldwin, John J., Claremon, David A.

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3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists von Biju, Purakkattle, Taveras, Arthur, Yu, Younong, Zheng, Junying, Chao, Jianhua, Rindgen, Diane, Jakway, James, Hipkin, R. William, Fossetta, James, Fan, Xuedong, Fine, Jay, Qiu, Hongchen, Merritt, J. Robert, Baldwin, John J.

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Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist von Chiba, Jun, Machinaga, Nobuo, Takashi, Tohru, Ejima, Akio, Takayama, Gensuke, Yokoyama, Mika, Nakayama, Atsushi, Baldwin, John J., McDonald, Edward, Saionz, Kurt W., Swanson, Robert, Hussain, Zahid, Wong, Angela

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On the use of the O-methylmandelate ester for establishment of absolute configuration of secondary alcohols von Trost, Barry M, Belletire, John L, Godleski, Stephen, McDougal, Patrick G, Balkovec, James M, Baldwin, John J, Christy, Marcia E, Ponticello, Gerald S, Varga, Sandor L, Springer, James P

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An electronic environment and contact direction sensitive scoring function for predicting affinities of protein–ligand complexes in Contour von Lindblom, Peter R., Wu, Guosheng, Liu, Zhijie, Jim, Kam-Chuen, Baldwin, John J., Gregg, Richard E., Claremon, David A., Singh, Suresh B.

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Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility von Jia, Lanqi, Simpson, Robert D, Yuan, Jing, Xu, Zhenrong, Zhao, Wei, Cacatian, Salvacion, Tice, Colin M, Guo, Joan, Ishchenko, Alexey, Singh, Suresh B, Wu, Zhongren, McKeever, Brian M, Bukhtiyarov, Yuri, Johnson, Judith A, Doe, Christopher P, Harrison, Richard K, McGeehan, Gerard M, Dillard, Lawrence W, Baldwin, John J, Claremon, David A

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Thienothiopyran-2-sulfonamides: novel topically active carbonic anhydrase inhibitors for the treatment of glaucoma von Baldwin, John J, Ponticello, Gerald S, Anderson, Paul S, Christy, Marcia E, Murcko, Mark A, Randall, William C, Schwam, Harvey, Sugrue, Michael F, Gautheron, Pierre

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III. Identification of novel CXCR3 chemokine receptor antagonists with a pyrazinyl–piperazinyl–piperidine scaffold von Kim, Seong Heon, Anilkumar, Gopinadhan N., Zawacki, Lisa Guise, Zeng, Qingbei, Yang, De-Yi, Shao, Yuefei, Dong, Guizhen, Xu, Xiaolian, Yu, Wensheng, Jiang, Yueheng, Jenh, Chung-Her, Hall, James W., Carroll, Carolyn DiIanni, Hobbs, Doug W., Baldwin, John J., McGuinness, Brian F., Rosenblum, Stuart B., Kozlowski, Joseph A., Shankar, Bandarpalle B., Shih, Neng-Yang

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Synthesis and structure–activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists von Merritt, J. Robert, Rokosz, Laura L., Nelson, Kingsley H., Kaiser, Bernd, Wang, Wei, Stauffer, Tara M., Ozgur, Lynne E., Schilling, Adriane, Li, Ge, Baldwin, John J., Taveras, Arthur G., Dwyer, Michael P., Chao, Jianping

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Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket von Yuan, Jing, Simpson, Robert D., Zhao, Wei, Tice, Colin M., Xu, Zhenrong, Cacatian, Salvacion, Jia, Lanqi, Flaherty, Patrick T., Guo, Joan, Ishchenko, Alexey, Wu, Zhongren, McKeever, Brian M., Scott, Boyd B., Bukhtiyarov, Yuri, Berbaum, Jennifer, Panemangalore, Reshma, Bentley, Ross, Doe, Christopher P., Harrison, Richard K., McGeehan, Gerard M., Singh, Suresh B., Dillard, Lawrence W., Baldwin, John J., Claremon, David A.

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Surfing the piperazine core of tricyclic farnesyltransferase inhibitors von Rokosz, Laura L., Huang, Chia-Yu, Reader, John C., Stauffer, Tara M., Chelsky, Daniel, Sigal, Nolan H., Ganguly, Ashit K., Baldwin, John J.

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Design and optimization of renin inhibitors: Orally bioavailable alkyl amines von Tice, Colin M., Xu, Zhenrong, Yuan, Jing, Simpson, Robert D., Cacatian, Salvacion T., Flaherty, Patrick T., Zhao, Wei, Guo, Joan, Ishchenko, Alexey, Singh, Suresh B., Wu, Zhongren, Scott, Boyd B., Bukhtiyarov, Yuri, Berbaum, Jennifer, Mason, Jennifer, Panemangalore, Reshma, Cappiello, Maria Grazia, Müller, Dominik, Harrison, Richard K., McGeehan, Gerard M., Dillard, Lawrence W., Baldwin, John J., Claremon, David A.

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Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists von Cole, Andrew G., Metzger, Axel, Brescia, Marc-Raleigh, Qin, Lan-Ying, Appell, Kenneth C., Brain, Christopher T., Hallett, Allan, Ganju, Pam, Denholm, Alastair A., Wareing, James R., Ritchie, Timothy J., Drake, Gillian M., Bevan, Stuart J., MacGloinn, Aisling, McBryde, Andrew, Patel, Viral, Oakley, Paul J., Nunez, Ximena, Gstach, Hubert, Schneider, Peter, Baldwin, John J., Dolle, Roland E., McDonald, Edward, Henderson, Ian

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Synthesis of a Small Molecule Combinatorial Library Encoded with Molecular Tags von Baldwin, John J, Burbaum, Jonathan J, Henderson, Ian, Ohlmeyer, Michael H. J

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Class III Antiarrhythmic Activity in Vivo by Selective Blockade of the Slowly Activating Cardiac Delayed Rectifier Potassium Current I Ks by (R)-2-(2,4- Trifluoromethyl)-N-[2-oxo-5... von Selnick, Harold G, Liverton, Nigel J, Baldwin, John J, Butcher, John W, Claremon, David A, Elliott, Jason M, Freidinger, Roger M, King, Stella A, Libby, Brian E, McIntyre, Charles J, Pribush, David A, Remy, David C, Smith, Garry R, Tebben, Andrew J, Jurkiewicz, Nancy K, Lynch, Joseph J, Salata, Joseph J, Sanguinetti, Michael C, Siegl, Peter K. S, Slaughter, Donald E, Vyas, Kamlesh

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