Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice von Bakker, Elvira R.M., Raghoebir, Lalini, Franken, Patrick F., Helvensteijn, Werner, van Gurp, Léon, Meijlink, Frits, van der Valk, Martin A., Rottier, Robbert J., Kuipers, Ernst J., van Veelen, Wendy, Smits, Ron

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LGR6-dependent conditional inactivation of E-cadherin and p53 leads to invasive skin and mammary carcinomas in mice von ter Steege, Eline J., Sijnesael, Thijmen, Enserink, Lotte, Klarenbeek, Sjoerd, Haakma, Wisse E., Bakker, Elvira R.M., Derksen, Patrick W.B.

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The role of R-spondin proteins in cancer biology von ter Steege, Eline J., Bakker, Elvira R. M.

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IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation von Ikink, Gerjon J., Boer, Mandy, Bakker, Elvira R. M., Hilkens, John

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R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach von Sigal, Michael, Reinés, Maria del Mar, Müllerke, Stefanie, Fischer, Cornelius, Kapalczynska, Marta, Berger, Hilmar, Bakker, Elvira R. M., Mollenkopf, Hans-Joachim, Rothenberg, Michael E., Wiedenmann, Bertram, Sauer, Sascha, Meyer, Thomas F.

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β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis von van Veelen, Wendy, Le, Ngoc H, Helvensteijn, Werner, Blonden, Lau, Theeuwes, Myrte, Bakker, Elvira R M, Franken, Patrick F, van Gurp, Léon, Meijlink, Frits, van der Valk, Martin A, Kuipers, Ernst J, Fodde, Riccardo, Smits, Ron

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R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling von ter Steege, Eline J., Doornbos, Loes W., Haughton, Peter D., van Diest, Paul J., Hilkens, John, Derksen, Patrick W.B., Bakker, Elvira R.M.

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Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer von Rätze, Max A. K., Koorman, Thijs, Sijnesael, Thijmen, Bassey-Archibong, Blessing, van de Ven, Robert, Enserink, Lotte, Visser, Daan, Jaksani, Sridevi, Viciano, Ignacio, Bakker, Elvira R. M., Richard, François, Tutt, Andrew, O’Leary, Lynda, Fitzpatrick, Amanda, Roca-Cusachs, Pere, van Diest, Paul J., Desmedt, Christine, Daniel, Juliet M., Isacke, Clare M., Derksen, Patrick W. B.

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R‐spondin‐3 is an oncogenic driver of poorly differentiated invasive breast cancer von Steege, Eline J, Boer, Mandy, Timmer, Nikki C, Ammerlaan, Carola ME, Song, Ji‐Ying, Derksen, Patrick WB, Hilkens, John, Bakker, Elvira RM

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Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation von Koopmans, Tim, Hesse, Laura, Nawijn, Martijn C., Kumawat, Kuldeep, Menzen, Mark H., Sophie T. Bos, I., Smits, Ron, Bakker, Elvira R. M., van den Berge, Maarten, Koppelman, Gerard H., Guryev, Victor, Gosens, Reinoud

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Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice von Lyraki, Rodanthi, Grabek, Anaëlle, Tison, Amélie, Weerasinghe Arachchige, Lahiru Chamara, Peitzsch, Mirko, Bechmann, Nicole, Youssef, Sameh A, de Bruin, Alain, Bakker, Elvira R M, Claessens, Frank, Chaboissier, Marie-Christine, Schedl, Andreas

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Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron von Lindström, Nils O, Lawrence, Melanie L, Burn, Sally F, Johansson, Jeanette A, Bakker, Elvira R M, Ridgway, Rachel A, Chang, C-Hong, Karolak, Michele J, Oxburgh, Leif, Headon, Denis J, Sansom, Owen J, Smits, Ron, Davies, Jamie A, Hohenstein, Peter

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Wnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice von Bakker, Elvira R M, Das, Asha Mooppilmadham, Helvensteijn, Werner, Franken, Patrick F, Swagemakers, Sigrid, van der Valk, Martin A, ten Hagen, Timo L M, Kuipers, Ernst J, van Veelen, Wendy, Smits, Ron

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Colorectal cancers choosing sides von Albuquerque, Cristina, Bakker, Elvira R.M., van Veelen, Wendy, Smits, Ron

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Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance von Ikink, Gerjon J., Boer, Mandy, Bakker, Elvira R. M., Vendel-Zwaagstra, Annabel, Klijn, Chris, ten Hoeve, Jelle, Jonkers, Jos, Wessels, Lodewyk F., Hilkens, John

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Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer von Ratze, Max A.K, Koorman, Thijs, Sijnesael, Thijmen, Bassey-Archibong, Blessing, van de Ven, Robert, Enserink, Lotte, Visser, Daan, Jaksani, Sridevi, Viciano, Ignacio, Bakker, Elvira R.M, Richard, Francois, Tutt, Andrew, O'Leary, Lynda, Fitzpatrick, Amanda, Roca-Cusachs, Pere, van Diest, Paul J, Desmedt, Christine, Daniel, Juliet M, Isacke, Clare M, Derksen, Patrick W.B

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Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice von Lyraki, Rodanthi, Grabek, Anaelle, Tison, Amelie, Arachchige, Lahiru Chamara Weerasinghe, Peitzsch, Mirko, Bechmann, Nicole, Youssef, Sameh A, de Bruin, Alain, Bakker, Elvira R.M, Claessens, Frank, Chaboissier, Marie-Christine, Schedl, Andreas

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RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis von Hilkens, John, Timmer, Nikki C, Boer, Mandy, Ikink, Gerjon J, Schewe, Matthias, Sacchetti, Andrea, Koppens, Martijn A J, Song, Ji-Ying, Bakker, Elvira R M

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SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype von Raghoebir, Lalini, Bakker, Elvira R M, Mills, Jason C, Swagemakers, Sigrid, Kempen, Marjon Buscop-van, Munck, Anne Boerema-de, Driegen, Siska, Meijer, Dies, Grosveld, Frank, Tibboel, Dick, Smits, Ron, Rottier, Robbert J

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Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity von Verhaar, Auke P., Hoekstra, Elmer, Tjon, Angela S. W., Utomo, Wesley K., Deuring, J. Jasper, Bakker, Elvira R. M., Muncan, Vanesa, Peppelenbosch, Maikel P.

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