Engineering tunable catch bonds with DNA von Yang, Micah, Bakker, David t. R., Li, Isaac T. S.

Volltext

Microbial Diversity Impacts Non-Protein Amino Acid Production in Cyanobacterial Bloom Cultures Collected from Lake Winnipeg von Bishop, Stephanie L, Solonenka, Julia T, Giebelhaus, Ryland T, Bakker, David T R, Li, Isaac T S, Murch, Susan J

Volltext

Microbial Diversity Impacts Non-Protein Amino Acid Production in Cyanobacterial Bloom Cultures Collected from Lake Winnipeg von Bishop, Stephanie L, Solonenka, Julia T, Giebelhaus, Ryland T, Bakker, David T. R, Li, Isaac T. S, Murch, Susan J

Volltext

HLA-A3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans von McCormack, Mark, Alfirevic, Ana, Bourgeois, Stephane, Farrell, John J, Kasperavičiūtė, Dalia, Carrington, Mary, Sills, Graeme J, Marson, Tony, Jia, Xiaoming, de Bakker, Paul I.W, Chinthapalli, Krishna, Molokhia, Mariam, Johnson, Michael R, O'Connor, Gerard D, Chaila, Elijah, Alhusaini, Saud, Shianna, Kevin V, Radtke, Rodney A, Heinzen, Erin L, Walley, Nicole, Pandolfo, Massimo, Pichler, Werner, Park, B. Kevin, Depondt, Chantal, Sisodiya, Sanjay M, Goldstein, David B, Deloukas, Panos, Delanty, Norman, Cavalleri, Gianpiero L, Pirmohamed, Munir

Volltext

Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program von JABLONSKI, Kathleen A, MCATEER, Jarred B, ALTSHULER, David, FLOREZ, Jose C, DE BAKKER, Paul I. W, FRANKS, Paul W, POLLIN, Toni I, HANSON, Robert L, SAXENA, Richa, FOWLER, Sarah, SHULDINER, Alan R, KNOWLER, William C

Volltext

TCF7L2 Polymorphisms and Progression to Diabetes in the Diabetes Prevention Program von Florez, Jose C, Jablonski, Kathleen A, Bayley, Nick, Pollin, Toni I, de Bakker, Paul I.W, Shuldiner, Alan R, Knowler, William C, Nathan, David M, Altshuler, David

Volltext

PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses von Purcell, Shaun, Neale, Benjamin, Todd-Brown, Kathe, Thomas, Lori, Ferreira, Manuel A.R., Bender, David, Maller, Julian, Sklar, Pamela, de Bakker, Paul I.W., Daly, Mark J., Sham, Pak C.

Volltext

Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects von Patsopoulos, Nikolaos A, Barcellos, Lisa F, Hintzen, Rogier Q, Schaefer, Catherine, van Duijn, Cornelia M, Noble, Janelle A, Raj, Towfique, Gourraud, Pierre-Antoine, Stranger, Barbara E, Oksenberg, Jorge, Olsson, Tomas, Taylor, Bruce V, Sawcer, Stephen, Hafler, David A, Carrington, Mary, De Jager, Philip L, de Bakker, Paul I W

Volltext

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci von Patsopoulos, Nikolaos A., de Bakker, Paul I. W.

Volltext

Efficiency and power in genetic association studies von de Bakker, Paul I W, Yelensky, Roman, Pe'er, Itsik, Gabriel, Stacey B, Daly, Mark J, Altshuler, David

Volltext

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load von McLaren, Paul J., Coulonges, Cedric, Bartha, István, Lenz, Tobias L., Deutsch, Aaron J., Bashirova, Arman, Buchbinder, Susan, Carrington, Mary N., Cossarizza, Andrea, Dalmau, Judith, De Luca, Andrea, Goedert, James J., Gurdasani, Deepti, Haas, David W., Herbeck, Joshua T., Johnson, Eric O., Kirk, Gregory D., Lambotte, Olivier, Luo, Ma, Mallal, Simon, van Manen, Daniëlle, Martinez-Picado, Javier, Meyer, Laurence, Miro, José M., Mullins, James I., Obel, Niels, Poli, Guido, Sandhu, Manjinder S., Schuitemaker, Hanneke, Shea, Patrick R., Theodorou, Ioannis, Walker, Bruce D., Weintrob, Amy C., Winkler, Cheryl A., Wolinsky, Steven M., Raychaudhuri, Soumya, Goldstein, David B., Telenti, Amalio, de Bakker, Paul I. W., Zagury, Jean-François, Fellay, Jacques

Volltext

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci von De Jager, Philip L, Jia, Xiaoming, Wang, Joanne, de Bakker, Paul I W, Ottoboni, Linda, Aggarwal, Neelum T, Piccio, Laura, Raychaudhuri, Soumya, Tran, Dong, Aubin, Cristin, Briskin, Rebeccah, Romano, Susan, Baranzini, Sergio E, McCauley, Jacob L, Pericak-Vance, Margaret A, Haines, Jonathan L, Gibson, Rachel A, Naeglin, Yvonne, Uitdehaag, Bernard, Matthews, Paul M, Kappos, Ludwig, Polman, Chris, McArdle, Wendy L, Strachan, David P, Evans, Denis, Cross, Anne H, Daly, Mark J, Compston, Alastair, Sawcer, Stephen J, Weiner, Howard L, Hauser, Stephen L, Hafler, David A, Oksenberg, Jorge R

Volltext

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis von Stahl, Eli A, Wegmann, Daniel, Trynka, Gosia, Gutierrez-Achury, Javier, Do, Ron, Voight, Benjamin F, Kraft, Peter, Chen, Robert, Kallberg, Henrik J, Kurreeman, Fina A S, Kathiresan, Sekar, Wijmenga, Cisca, Gregersen, Peter K, Alfredsson, Lars, Siminovitch, Katherine A, Worthington, Jane, de Bakker, Paul I W, Raychaudhuri, Soumya, Plenge, Robert M

Volltext

Integrating common and rare genetic variation in diverse human populations von Altshuler, David M, Gibbs, Richard A, Peltonen, Leena, Dermitzakis, Emmanouil, Schaffner, Stephen F, Yu, Fuli, Bonnen, Penelope E, de Bakker, Paul I W, Deloukas, Panos, Gabriel, Stacey B, Gwilliam, Rhian, Hunt, Sarah, Inouye, Michael, Jia, Xiaoming, Palotie, Aarno, Parkin, Melissa, Whittaker, Pamela, Chang, Kyle, Hawes, Alicia, Lewis, Lora R, Ren, Yanru, Wheeler, David, Muzny, Donna Marie, Barnes, Chris, Darvishi, Katayoon, Hurles, Matthew, Korn, Joshua M, Kristiansson, Kati, Lee, Charles, McCarrol, Steven A, Nemesh, James, Keinan, Alon, Montgomery, Stephen B, Pollack, Samuela, Price, Alkes L, Soranzo, Nicole, Gonzaga-Jauregui, Claudia, Anttila, Verneri, Brodeur, Wendy, Daly, Mark J, Leslie, Stephen, McVean, Gil, Moutsianas, Loukas, Nguyen, Huy, Zhang, Qingrun, Ghori, Mohammed J R, McGinnis, Ralph, McLaren, William, Takeuchi, Fumihiko, Grossman, Sharon R, Shlyakhter, Ilya, Hostetter, Elizabeth B, Sabeti, Pardis C, Adebamowo, Clement A, Foster, Morris W, Gordon, Deborah R, Licinio, Julio, Manca, Maria Cristina, Marshall, Patricia A, Matsuda, Ichiro, Ngare, Duncan, Wang, Vivian Ota, Reddy, Deepa, Rotimi, Charles N, Royal, Charmaine D, Sharp, Richard R, Zeng, Changqing, Brooks, Lisa D, McEwen, Jean E

Volltext

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis von Plenge, Robert M, Cotsapas, Chris, Davies, Leela, Price, Alkes L, de Bakker, Paul I W, Maller, Julian, Pe'er, Itsik, Burtt, Noel P, Blumenstiel, Brendan, DeFelice, Matt, Parkin, Melissa, Barry, Rachel, Winslow, Wendy, Healy, Claire, Graham, Robert R, Neale, Benjamin M, Izmailova, Elena, Roubenoff, Ronenn, Parker, Alexander N, Glass, Roberta, Karlson, Elizabeth W, Maher, Nancy, Hafler, David A, Lee, David M, Seldin, Michael F, Remmers, Elaine F, Lee, Annette T, Padyukov, Leonid, Alfredsson, Lars, Coblyn, Jonathan, Weinblatt, Michael E, Gabriel, Stacey B, Purcell, Shaun, Klareskog, Lars, Gregersen, Peter K, Shadick, Nancy A, Daly, Mark J, Altshuler, David

Volltext

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis von Chaker, Layal, Baumgartner, Christine, den Elzen, Wendy P. J, Ikram, M. Arfan, Blum, Manuel R, Collet, Tinh-Hai, Bakker, Stephan J. L, Dehghan, Abbas, Drechsler, Christiane, Luben, Robert N, Hofman, Albert, Portegies, Marileen L. P, Medici, Marco, Iervasi, Giorgio, Stott, David J, Ford, Ian, Bremner, Alexandra, Wanner, Christoph, Ferrucci, Luigi, Newman, Anne B, Dullaart, Robin P, Sgarbi, José A, Ceresini, Graziano, Maciel, Rui M. B, Westendorp, Rudi G, Jukema, J. Wouter, Imaizumi, Misa, Franklyn, Jayne A, Bauer, Douglas C, Walsh, John P, Razvi, Salman, Khaw, Kay-Tee, Cappola, Anne R, Völzke, Henry, Franco, Oscar H, Gussekloo, Jacobijn, Rodondi, Nicolas, Peeters, Robin P

Volltext

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation von Adlam, David, Berrandou, Takiy-Eddine, Georges, Adrien, Nelson, Christopher P., Giannoulatou, Eleni, Henry, Joséphine, Ma, Lijiang, Blencowe, Montgomery, Turley, Tamiel N., Yang, Min-Lee, Chopade, Sandesh, Finan, Chris, Braund, Peter S., Sadeg-Sayoud, Ines, Iismaa, Siiri E., Kosel, Matthew L., Zhou, Xiang, Hamby, Stephen E., Cheng, Jenny, Liu, Lu, Tarr, Ingrid, Muller, David W. M., d’Escamard, Valentina, King, Annette, Brunham, Liam R., Baranowska-Clarke, Ania A., Debette, Stéphanie, Amouyel, Philippe, Olin, Jeffrey W., Patil, Snehal, Hesselson, Stephanie E., Junday, Keerat, Kanoni, Stavroula, Aragam, Krishna G., Butterworth, Adam S., Tweet, Marysia S., Gulati, Rajiv, Combaret, Nicolas, Kadian-Dodov, Daniella, Kalman, Jonathan M., Fatkin, Diane, Hingorani, Aroon D., Saw, Jacqueline, Webb, Tom R., Hayes, Sharonne N., Yang, Xia, Ganesh, Santhi K., Olson, Timothy M., Kovacic, Jason C., Graham, Robert M., Samani, Nilesh J., Bouatia-Naji, Nabila

Volltext

Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates von Palamara, Pier Francesco, Francioli, Laurent C., Wilton, Peter R., Genovese, Giulio, Gusev, Alexander, Finucane, Hilary K., Sankararaman, Sriram, Sunyaev, Shamil R., de Bakker, Paul I.W., Wakeley, John, Pe’er, Itsik, Price, Alkes L.

Volltext

role of the CD58 locus in multiple sclerosis von De Jager, Philip L, Baecher-Allan, Clare, Maier, Lisa M, Arthur, Ariel T, Ottoboni, Linda, Barcellos, Lisa, McCauley, Jacob L, Sawcer, Stephen, Goris, An, Saarela, Janna, Yelensky, Roman, Price, Alkes, Leppa, Virpi, Patterson, Nick, de Bakker, Paul I.W, Tran, Dong, Aubin, Cristin, Pobywajlo, Susan, Rossin, Elizabeth, Hu, Xinli, Ashley, Charles W, Choy, Edwin, Rioux, John D, Pericak-Vance, Margaret A, Ivinson, Adrian, Booth, David R, Stewart, Graeme J, Palotie, Aarno, Peltonen, Leena, Dubois, Bénédicte, Haines, Jonathan L, Weiner, Howard L, Compston, Alastair, Hauser, Stephen L, Daly, Mark J, Reich, David, Oksenberg, Jorge R, Hafler, David A

Volltext

Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis von Paige, Ellie, Barrett, Jessica, Pennells, Lisa, Sweeting, Michael, Willeit, Peter, Di Angelantonio, Emanuele, Gudnason, Vilmundur, Nordestgaard, Børge G, Psaty, Bruce M, Goldbourt, Uri, Best, Lyle G, Assmann, Gerd, Salonen, Jukka T, Nietert, Paul J, Verschuren, W M Monique, Brunner, Eric J, Kronmal, Richard A, Salomaa, Veikko, Bakker, Stephan J L, Dagenais, Gilles R, Sato, Shinichi, Jansson, Jan-Håkan, Willeit, Johann, Onat, Altan, de la Cámara, Agustin Gómez, Roussel, Ronan, Völzke, Henry, Dankner, Rachel, Tipping, Robert W, Meade, Tom W, Donfrancesco, Chiara, Kuller, Lewis H, Peters, Annette, Gallacher, John, Kromhout, Daan, Iso, Hiroyasu, Knuiman, Matthew, Casiglia, Edoardo, Kavousi, Maryam, Palmieri, Luigi, Sundström, Johan, Davis, Barry R, Njølstad, Inger, Couper, David, Danesh, John, Thompson, Simon G, Wood, Angela

Volltext