375-P: Indirect Treatment Comparison (ITC) of Three Ready-to-Use Glucagon Treatments for Severe Hypoglycemia: Baqsimi, Gvoke, and Zegalogue von GIMENEZ, MARGA, KHUNTI, KAMLESH, SYRING, KRISTEN, BAKER, LEVENIA A., CHENJI, SURESH, THRELKELD, REBECCA J., YAN, YU, MATSUHISA, MUNEHIDE

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10-LB: Psychosocial Impact of Severe Hypoglycemia and Perceptions of Nasal Glucagon in Young Adults with Type 1 Diabetes von KELLY, CAITLIN S., NGUYEN, HUYEN, LUO, WEIXIU, CHAPMAN, KATHERINE S.M., POON, JIAT LING, BAKER, LEVENIA A., WOLF, WENDY, PEREZ-NIEVES, MAGALY, MITCHELL, BETH

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The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats von Erion, Derek M, Lapworth, Amanda, Amor, Paul A, Bai, Guoyun, Vera, Nicholas B, Clark, Ronald W, Yan, Qingyun, Zhu, Yimin, Ross, Trenton T, Purkal, Julie, Gorgoglione, Matthew, Zhang, Guodong, Bonato, Vinicius, Baker, Levenia, Barucci, Nicole, D'Aquila, Theresa, Robertson, Alan, Aiello, Robert J, Yan, Jiangli, Trimmer, Jeff, Rolph, Timothy P, Pfefferkorn, Jeffrey A

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Emerging Adult and Caregiver Psychosocial Experiences with Severe Hypoglycemic Events and the Perceived Impact of Nasal Glucagon: A Cross-Sectional Study von Kelly, Caitlin S., Nguyen, Huyen, Luo, Weixiu, Chapman, Katherine, Poon, Jiat-Ling, Perez-Nieves, Magaly, Baker, Levenia, Wolf, Wendy A., Mitchell, Beth

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Discovery of (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type... von Pfefferkorn, Jeffrey A, Guzman-Perez, Angel, Litchfield, John, Aiello, Robert, Treadway, Judith L, Pettersen, John, Minich, Martha L, Filipski, Kevin J, Jones, Christopher S, Tu, Meihua, Aspnes, Gary, Risley, Hud, Bian, Jianwei, Stevens, Benjamin D, Bourassa, Patricia, D’Aquila, Theresa, Baker, Levenia, Barucci, Nicole, Robertson, Alan S, Bourbonais, Francis, Derksen, David R, MacDougall, Margit, Cabrera, Over, Chen, Jing, Lapworth, Amanda Lee, Landro, James A, Zavadoski, William J, Atkinson, Karen, Haddish-Berhane, Nahor, Tan, Beijing, Yao, Lili, Kosa, Rachel E, Varma, Manthena V, Feng, Bo, Duignan, David B, El-Kattan, Ayman, Murdande, Sharad, Liu, Shenping, Ammirati, Mark, Knafels, John, DaSilva-Jardine, Paul, Sweet, Laurel, Liras, Spiros, Rolph, Timothy P

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The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of Type 2 diabetes mellitus von Pfefferkorn, Jeffrey A., Tu, Meihua, Filipski, Kevin J., Guzman-Perez, Angel, Bian, Jianwei, Aspnes, Gary E., Sammons, Matthew F., Song, Wei, Li, Jian-Cheng, Jones, Christopher S., Patel, Leena, Rasmusson, Tim, Zeng, Dongxiang, Karki, Kapil, Hamilton, Michael, Hank, Richard, Atkinson, Karen, Litchfield, John, Aiello, Robert, Baker, Levenia, Barucci, Nicole, Bourassa, Patricia, Bourbounais, Francis, D’Aquila, Theresa, Derksen, David R., MacDougall, Margit, Robertson, Alan

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Region specific increase in the antioxidant enzymes and lipid peroxidation products in the brain of rats exposed to lead von Bennet, Christopher, Bettaiya, Rajanna, Rajanna, Sharada, Baker, Levenia, Yallapragada, Prabhakara Rao, Brice, Jon J., White, Samuel L., Bokara, Kiran Kumar

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Corrigendum to “The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of Type 2 diabetes mellitus” [Bioorg. Med. Chem. Lett. 22 (... von Pfefferkorn, Jeffrey A., Tu, Meihua, Filipski, Kevin J., Guzman-Perez, Angel, Bian, Jianwei, Aspnes, Gary E., Sammons, Matthew F., Song, Wei, Li, Jian-Cheng, Jones, Christopher S., Patel, Leena, Rasmusson, Tim, Zeng, Dongxiang, Karki, Kapil, Hamilton, Michael, Hank, Richard, Atkinson, Karen, Litchfield, John, Aiello, Robert, Baker, Levenia, Barucci, Nicole, Bourassa, Patricia, Bourbonais, Francis, D’Aquila, Theresa, Derksen, David R., MacDougall, Margit, Robertson, Alan

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Optimizing glucokinase activator binding kinetics to lower in vivo hypoglycemia risk von Borzilleri, Kris A., Pfefferkorn, Jeffrey A., Guzman-Perez, Angel, Liu, Shenping, Qiu, Xiayang, Chrunyk, Boris A., Song, Xi, Tu, Meihua, Filipski, Kevin J., Aiello, Robert, Derksen, David R., Bourbonais, Francis J., Landro, James, Bourassa, Patricia, D'Aquila, Theresa, Baker, Levenia, Barrucci, Nicole, Litchfield, John, Atkinson, Karen, Rolph, Timothy P., Withka, Jane M.

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Discovery of ( S )-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1 H -imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating... von Pfefferkorn, Jeffrey A., Guzman-Perez, Angel, Litchfield, John, Aiello, Robert, Treadway, Judith L., Pettersen, John, Minich, Martha L., Filipski, Kevin J., Jones, Christopher S., Tu, Meihua, Aspnes, Gary, Risley, Hud, Bian, Jianwei, Stevens, Benjamin D., Bourassa, Patricia, D’Aquila, Theresa, Baker, Levenia, Barucci, Nicole, Robertson, Alan S., Bourbonais, Francis, Derksen, David R., MacDougall, Margit, Cabrera, Over, Chen, Jing, Lapworth, Amanda Lee, Landro, James A., Zavadoski, William J., Atkinson, Karen, Haddish-Berhane, Nahor, Tan, Beijing, Yao, Lili, Kosa, Rachel E., Varma, Manthena V., Feng, Bo, Duignan, David B., El-Kattan, Ayman, Murdande, Sharad, Liu, Shenping, Ammirati, Mark, Knafels, John, DaSilva-Jardine, Paul, Sweet, Laurel, Liras, Spiros, Rolph, Timothy P.

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Optimizing glucokinase activator binding kinetics to lower in vivo hypoglycemia riskElectronic supplementary information (ESI) available: SPR profiles for compounds 6 and 15, KD an... von Borzilleri, Kris A, Pfefferkorn, Jeffrey A, Guzman-Perez, Angel, Liu, Shenping, Qiu, Xiayang, Chrunyk, Boris A, Song, Xi, Tu, Meihua, Filipski, Kevin J, Aiello, Robert, Derksen, David R, Bourbonais, Francis J, Landro, James, Bourassa, Patricia, D'Aquila, Theresa, Baker, Levenia, Barrucci, Nicole, Litchfield, John, Atkinson, Karen, Rolph, Timothy P, Withka, Jane M

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