MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts von Zhang, Xiaomeng, Wojtkowiak, Jonathan W, Martinez, Gary V, Cornnell, Heather H, Hart, Charles P, Baker, Amanda F, Gillies, Robert

Volltext

Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer von Bailey, Kate M, Cornnell, Heather H, Ibrahim-Hashim, Arig, Wojtkowiak, Jonathan W, Hart, Charles P, Zhang, Xiaomeng, Leos, Rafael, Martinez, Gary V, Baker, Amanda F, Gillies, Robert J

Volltext

Phase II Trial of Erlotinib in Gastroesophageal Junction and Gastric Adenocarcinomas: SWOG 0127 von DRAGOVICH, Tomislav, MCCOY, Sheryl, ABBRUZZESE, James L, FENOGLIO-PREISER, Cecilia M, JIANG WANG, BENEDETTI, Jacqueline K, BAKER, Amanda F, HACKETT, Christopher B, URBA, Susan G, ZANER, Ken S, BLANKE, Charles D

Volltext

Characterization of carfilzomib-resistant non-small cell lung cancer cell lines von Hanke, Neale T., Imler, Elliot, Marron, Marilyn T., Seligmann, Bruce E., Garland, Linda L., Baker, Amanda F.

Volltext

Reproducibility of magnetic resonance perfusion imaging von Zhang, Xiaomeng, Pagel, Mark D, Baker, Amanda F, Gillies, Robert J

Volltext

Carfilzomib demonstrates broad anti-tumor activity in pre-clinical non-small cell and small cell lung cancer models von Baker, Amanda F, Hanke, Neale T, Sands, Barbara J, Carbajal, Liliana, Anderl, Janet L, Garland, Linda L

Volltext

Stability of Phosphoprotein as a Biological Marker of Tumor Signaling von BAKER, Amanda F, DRAGOVICH, Tomislav, IHLE, Nathan T, WILLIAMS, Ryan, FENOGLIO-PREISER, Cecilia, POWIS, Garth

Volltext

Overexpression of Tumor Vascular Endothelial Growth Factor A May Portend an Increased Likelihood of Progression in a Phase II Trial of Bevacizumab and Erlotinib in Resistant Ovaria... von CHAMBERS, Setsuko K, CLOUSER, Mary C, GORDON, Alan N, NAGLE, Raymond B, WRIGHT, Heather M, COHEN, Janice L, ALBERTS, David S, BAKER, Amanda F, ROE, Denise J, HAIYAN CUI, BREWER, Molly A, HATCH, Kenneth D, GORDON, Michael S, JANICEK, Mike F, ISAACS, Jeffrey D

Volltext

Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI von Akhenblit, Paul J., Hanke, Neale T., Gill, Alexander, Persky, Daniel O., Howison, Christine M., Pagel, Mark D., Baker, Amanda F.

Volltext

Management strategies in pancreatic cancer von Campen, Christopher J, Dragovich, Tomislav, Baker, Amanda F

Volltext

Imaging biomarkers to monitor response to the hypoxia-activated prodrug TH-302 in the MiaPaCa2 flank xenograft model von Cárdenas-Rodríguez, Julio, Li, Yuguo, Galons, Jean-Philippe, Cornnell, Heather, Gillies, Robert J, Pagel, Mark D, Baker, Amanda F

Volltext

Opportunities and Challenges of Safety Biomarker Qualification: Perspectives from the Predictive Safety Testing Consortium von Dennis, Eslie H., Walker, Elizabeth G., Baker, Amanda F., Miller, Richard T.

Volltext

Detecting in vivo urokinase plasminogen activator activity with a catalyCEST MRI contrast agent von Sinharay, Sanhita, Howison, Christine M., Baker, Amanda F., Pagel, Mark D.

Volltext

Evaluation of a Hypoxia Regulated Gene Panel in Ovarian Cancer von Baker, Amanda F., Malm, Scott W., Pandey, Ritu, Laughren, Cindy, Cui, Haiyan, Roe, Denise, Chambers, Setsuko K.

Volltext

The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resona... von JORDAN, Bénédicte F, RUNQUIST, Matthew, RAGHUNAND, Natarajan, GILLIES, Robert J, TATE, Wendy R, POWIS, Garth, BAKER, Amanda F

Volltext

Carfilzomib combined with suberanilohydroxamic acid (SAHA) synergistically promotes endoplasmic reticulum stress in non-small cell lung cancer cell lines von Hanke, Neale T., Garland, Linda L., Baker, Amanda F.

Volltext

randomized phase II study of PX-12, an inhibitor of thioredoxin in patients with advanced cancer of the pancreas following progression after a gemcitabine-containing combination von Ramanathan, Ramesh K, Abbruzzese, James, Dragovich, Tomislav, Kirkpatrick, Lynn, Guillen, Jose M, Baker, Amanda F, Pestano, Linda A, Green, Sylvan, Von Hoff, Daniel D

Volltext

The anti-tumor efficacy of 2-deoxyglucose and D-allose are enhanced with p38 inhibition in pancreatic and ovarian cell lines von Malm, Scott W, Hanke, Neale T, Gill, Alexander, Carbajal, Liliana, Baker, Amanda F

Volltext

Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase von Kim, Yon Hui, Coon, Amy, Baker, Amanda F., Powis, Garth

Volltext

TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules von Liu, Qian, Sun, Jessica D., Wang, Jingli, Ahluwalia, Dharmendra, Baker, Amanda F., Cranmer, Lee D., Ferraro, Damien, Wang, Yan, Duan, Jian-Xin, Ammons, W. Steve, Curd, John G., Matteucci, Mark D., Hart, Charles P.

Volltext