1215P Comparative analysis of cfDNA liquid biopsy and tumor-based next-generation sequencing (NGS) approaches von Yudina, A., Starikov, S., Efremov, A., Sookiasian, D., Nuzhdina, E., Podsvirova, S., Chasse, M., Conroy, T., English, N., Love, A., Tabakov, D., Baisangurov, A., Tazearslan, C., Fowler, N., Bagaev, A.

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Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes von Zaitsev, Aleksandr, Chelushkin, Maksim, Dyikanov, Daniiar, Cheremushkin, Ilya, Shpak, Boris, Nomie, Krystle, Zyrin, Vladimir, Nuzhdina, Ekaterina, Lozinsky, Yaroslav, Zotova, Anastasia, Degryse, Sandrine, Kotlov, Nikita, Baisangurov, Artur, Shatsky, Vladimir, Afenteva, Daria, Kuznetsov, Alexander, Paul, Susan Raju, Davies, Diane L., Reeves, Patrick M., Lanuti, Michael, Goldberg, Michael F., Tazearslan, Cagdas, Chasse, Madison, Wang, Iris, Abdou, Mary, Aslanian, Sharon M., Andrewes, Samuel, Hsieh, James J., Ramachandran, Akshaya, Lyu, Yang, Galkin, Ilia, Svekolkin, Viktor, Cerchietti, Leandro, Poznansky, Mark C., Ataullakhanov, Ravshan, Fowler, Nathan, Bagaev, Alexander

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A Novel Comprehensive Tumor-Informed Plasma cfDNA Assay to Monitor Minimal Residual Disease for Hematological and Solid Malignancies von Yudina, Anastasiya, Danchurova, Anastasiya, Alekseeva, Lolita, Efremov, Aleksei, Starikov, Sergei, Sookiasian, Danielle, Nuzhdina, Ekaterina, Podsvirova, Svetlana, Chasse, Madison, Conroy, Tori, English, Noel, Tabakov, Dmitry, Yong, Sheila T., Baisangurov, Artur, Tazearslan, Cagdas, Fowler, Nathan, Bagaev, Alexander

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Analytical and clinical validation of the BostonGene tumor portrait assay von Nuzhdina, Katerina, Lozinsky, Yaroslav, Podsvirova, Svetlana, Baisangurov, Arthur, Morgan, Kelley, Kaneunyenye, Leznath, Sivkov, Anton, Starikov, Sergey, Segodin, Vitaly, Kuzkina, Natalia, Frenkel, Felix, Brown, Jessica, Curran, John, Bagaev, Alexander, Fowler, Nathan

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Procrustes is a machine-learning approach that removes cross-platform batch effects from clinical RNA sequencing data von Kotlov, Nikita, Shaposhnikov, Kirill, Tazearslan, Cagdas, Chasse, Madison, Baisangurov, Artur, Podsvirova, Svetlana, Fernandez, Dawn, Abdou, Mary, Kaneunyenye, Leznath, Morgan, Kelley, Cheremushkin, Ilya, Zemskiy, Pavel, Chelushkin, Maxim, Sorokina, Maria, Belova, Ekaterina, Khorkova, Svetlana, Lozinsky, Yaroslav, Nuzhdina, Katerina, Vasileva, Elena, Kravchenko, Dmitry, Suryamohan, Kushal, Nomie, Krystle, Curran, John, Fowler, Nathan, Bagaev, Alexander

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Abstract 853: Novel machine learning based deconvolution algorithm results in accurate description of tumor microenvironment from bulk RNAseq von Zaytcev, Alexander, Chelushkin, Maxim, Nuzhdina, Katerina, Bagaev, Alexander, Dyykanov, Daniyar, Zyrin, Vladimir, Paul, Susan Raju, Davies, Diane L., Reeves, Patrick M., Lanuti, Michael, Poznansky, Mark C., Baisangurov, Arthtur, Ataullakhanov, Ravshan, Fowler, Nathan

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Abstract 1042: Analytical validation of a liquid biopsy test using cell-free circulating tumor DNA for mutational profiling von Yudina, Anastasiya, Efremov, Alexey, Sookiasian, Danielle, Nuzhdina, Ekaterina, Podsvirova, Svetlana, Chasse, Madison, Conroy, Tori, English, Noel, Starikov, Sergey, Klimchuk, Olesia, Tabakov, Dmitry, Love, Anna, Suryamohan, Kushal, Baisangurov, Artur, Tazearslan, Cagdas, Fowler, Nathan, Bagaev, Alexander

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Abstract 1216: Combinatory technologies for single sample gene expression projection onto a cohort sequenced with a different technology for personalized clinical decision-making von Kotlov, Nikita, Shaposhnikov, Kirill, Tazearslan, Cagdas, Cheremushkin, Ilya, Chasse, Madison, Baisangurov, Artur, Podsvirova, Svetlana, Korkova, Svetlana, Lozinsky, Yaroslav, Nuzhdina, Katerina, Vasileva, Elena, Kravchenko, Dmitry, Nomie, Krystle, Curran, John, Fowler, Nathan, Bagaev, Alexander

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TECHNIQUES FOR SINGLE SAMPLE EXPRESSION PROJECTION TO AN EXPRESSION COHORT SEQUENCED WITH ANOTHER PROTOCOL von Tazearslan, Cagdas, Chelushkin, Maksim, Kravchenko, Dmitry, Bagaev, Alexander, Podsvirova, Svetlana, Cheremushkin, IIya, Postovalova, Ekaterina, Baisangurov, Artur, Shaposhnikov, Kirill, Kotlov, Nikita, Khorkova, Svetlana

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TECHNIQUES FOR SINGLE SAMPLE EXPRESSION PROJECTION TO AN EXPRESSION COHORT SEQUENCED WITH ANOTHER PROTOCOL von SHAPOSHNIKOV, Kirill, CHEREMUSHKIN, Ilya, KRAVCHENKO, Dmitry, KOTLOV, Nikita, TAZEARSLAN, Cagdas, BAGAEV, Alexander, CHELUSHKIN, Maksim, POSTOVALOVA, Ekaterina, KHORKOVA, Svetlana, BAISANGUROV, Artur, PODSVIROVA, Svetlana

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TECHNIQUES FOR SINGLE SAMPLE EXPRESSION PROJECTION TO AN EXPRESSION COHORT SEQUENCED WITH ANOTHER PROTOCOL von SHAPOSHNIKOV, Kirill, CHEREMUSHKIN, Ilya, KRAVCHENKO, Dmitry, KOTLOV, Nikita, TAZEARSLAN, Cagdas, BAGAEV, Alexander, CHELUSHKIN, Maksim, POSTOVALOVA, Ekaterina, KHORKOVA, Svetlana, BAISANGUROV, Artur, PODSVIROVA, Svetlana

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TECHNIQUES FOR SINGLE SAMPLE EXPRESSION PROJECTION TO AN EXPRESSION COHORT SEQUENCED WITH ANOTHER PROTOCOL von Tazearslan, Cagdas, Chelushkin, Maksim, Kravchenko, Dmitry, Bagaev, Alexander, Podsvirova, Svetlana, Postovalova, Ekaterina, Cheremushkin, Ilya, Baisangurov, Artur, Shaposhnikov, Kirill, Kotlov, Nikita, Khorkova, Svetlana

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TECHNIQUES FOR SINGLE SAMPLE EXPRESSION PROJECTION TO AN EXPRESSION COHORT SEQUENCED WITH ANOTHER PROTOCOL von SHAPOSHNIKOV, Kirill, CHEREMUSHKIN, Ilya, KRAVCHENKO, Dmitry, KOTLOV, Nikita, TAZEARSLAN, Cagdas, BAGAEV, Alexander, POSTOVALOVA, Ekaterina, CHELUSHKIN, Maksim, KHORKOVA, Svetlana, BAISANGUROV, Artur, PODSVIROVA, Svetlana

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TECHNIQUES FOR SINGLE SAMPLE EXPRESSION PROJECTION TO AN EXPRESSION COHORT SEQUENCED WITH ANOTHER PROTOCOL von TAZEARSLAN, CAGDAS, KRAVCHENKO, DMITRY, KOTLOV, NIKITA, CHELUSHKIN, MAKSIM, PODSVIROVA, SVETLANA, POSTOVALOVA, EKATERINA, SHAPOSHNIKOV, KIRILL, CHEREMUSHKIN, ILYA, KHORKOVA, SVETLANA, BAISANGUROV, ARTUR, BAGAEV, ALEXANDER

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