A high-fat diet promotes depression-like behavior in mice by suppressing hypothalamic PKA signaling von Vagena, Eirini, Ryu, Jae Kyu, Baeza-Raja, Bernat, Walsh, Nicola M., Syme, Catriona, Day, Jonathan P., Houslay, Miles D., Baillie, George S.

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Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function von Zou, Zhi-Guo, Rios, Francisco J, Neves, Karla B, Alves-Lopes, Rheure, Ling, Jiayue, Baillie, George S, Gao, Xing, Fuller, William, Camargo, Livia L, Gudermann, Thomas, Chubanov, Vladimir, Montezano, Augusto C, Touyz, Rhian M

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Phosphodiesterase 4B: Master Regulator of Brain Signaling von Tibbo, Amy J, Baillie, George S

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The enigmatic helicase DHX9 and its association with the hallmarks of cancer von Gulliver, Chloe, Hoffmann, Ralf, Baillie, George S

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Short PDE4 Isoforms as Drug Targets in Disease von Kyurkchieva, Elka, Baillie, George S

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TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells von Diamantopoulou, Zoi, White, Gavin, Fadlullah, Muhammad Z.H., Dreger, Marcel, Pickering, Karen, Maltas, Joe, Ashton, Garry, MacLeod, Ruth, Baillie, George S., Kouskoff, Valerie, Lacaud, Georges, Murray, Graeme I., Sansom, Owen J., Hurlstone, Adam F.L., Malliri, Angeliki

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Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1 von Havekes, Robbert, Park, Alan J, Tudor, Jennifer C, Luczak, Vincent G, Hansen, Rolf T, Ferri, Sarah L, Bruinenberg, Vibeke M, Poplawski, Shane G, Day, Jonathan P, Aton, Sara J, Radwańska, Kasia, Meerlo, Peter, Houslay, Miles D, Baillie, George S, Abel, Ted

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Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling von Rutherford, Claire, Speirs, Claire, Williams, Jamie J L, Ewart, Marie-Ann, Mancini, Sarah J, Hawley, Simon A, Delles, Christian, Viollet, Benoit, Costa-Pereira, Ana P, Baillie, George S, Salt, Ian P, Palmer, Timothy M

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PDE4-Mediated cAMP Signalling von Fertig, Bracy A, Baillie, George S

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Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2 von Zoccarato, Anna, Surdo, Nicoletta C, Aronsen, Jan M, Fields, Laura A, Mancuso, Luisa, Dodoni, Giuliano, Stangherlin, Alessandra, Livie, Craig, Jiang, He, Sin, Yuan Yan, Gesellchen, Frank, Terrin, Anna, Baillie, George S, Nicklin, Stuart A, Graham, Delyth, Szabo-Fresnais, Nicolas, Krall, Judith, Vandeput, Fabrice, Movsesian, Matthew, Furlan, Leonardo, Corsetti, Veronica, Hamilton, Graham, Lefkimmiatis, Konstantinos, Sjaastad, Ivar, Zaccolo, Manuela

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Therapeutic targeting of 3′,5′-cyclic nucleotide phosphodiesterases: inhibition and beyond von Baillie, George S., Tejeda, Gonzalo S., Kelly, Michy P.

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cAMP‐phosphodiesterase 4D7 (PDE4D7) forms a cAMP signalosome complex with DHX9 and is implicated in prostate cancer progression von Gulliver, Chloe, Busiau, Tara, Byrne, Ashleigh, Findlay, Jane E., Hoffmann, Ralf, Baillie, George S.

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PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding von Christian, Frank, Krause, Eberhard, Houslay, Miles D., Baillie, George S.

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Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ von Perino, Alessia, Ghigo, Alessandra, Ferrero, Enrico, Morello, Fulvio, Santulli, Gaetano, Baillie, George S, Damilano, Federico, Dunlop, Allan J, Pawson, Catherine, Walser, Romy, Levi, Renzo, Altruda, Fiorella, Silengo, Lorenzo, Langeberg, Lorene K, Neubauer, Gitte, Heymans, Stephane, Lembo, Giuseppe, Wymann, Matthias P, Wetzker, Reinhard, Houslay, Miles D, Iaccarino, Guido, Scott, John D, Hirsch, Emilio

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Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies von Main, Alice, Boguslavskyi, Andri, Howie, Jacqueline, Kuo, Chien-Wen, Rankin, Aileen, Burton, Francis L, Smith, Godfrey L, Hajjar, Roger, Baillie, George S, Campbell, Kenneth S, Shattock, Michael J, Fuller, William

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Reduced PDE4D7 in prostate cancer correlates with genomic downregulation within the upstream PDE4D coding region von Gulliver, Chloe, Baillie, George S, Hoffmann, Ralf

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Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases von Baillie, George S

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Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability von Williams, Jamie J. L., Alotaiq, Nasser, Mullen, William, Burchmore, Richard, Liu, Libin, Baillie, George S., Schaper, Fred, Pilch, Paul F., Palmer, Timothy M.

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Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition von McGirr, Alexander, Lipina, Tatiana V, Mun, Ho-Suk, Georgiou, John, Al-Amri, Ahmed H, Ng, Enoch, Zhai, Dongxu, Elliott, Christina, Cameron, Ryan T, Mullins, Jonathan G L, Liu, Fang, Baillie, George S, Clapcote, Steven J, Roder, John C

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Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC von Cooke, Sean F., Wright, Thomas A., Sin, Yuan Yan, Ling, Jiayue, Kyurkchieva, Elka, Phanthaphol, Nattaporn, Mcskimming, Thomas, Herbert, Katharine, Rebus, Selma, Biankin, Andrew V., Chang, David K., Baillie, George S., Blair, Connor M.

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