Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization von Asokan, M, Rudicell, R S, Louder, M, McKee, K, O'Dell, S, Stewart-Jones, G, Wang, K, Xu, L, Chen, X, Choe, M, Chuang, G, Georgiev, I S, Joyce, M G, Kirys, T, Ko, S, Pegu, A, Shi, W, Todd, J P, Yang, Z, Bailer, R T, Rao, S, Kwong, P D, Nabel, G J, Mascola, J R

Volltext

A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults von Ledgerwood, J.E, Costner, P, Desai, N, Holman, L, Enama, M.E, Yamshchikov, G, Mulangu, S, Hu, Z, Andrews, C.A, Sheets, R.A, Koup, R.A, Roederer, M, Bailer, R, Mascola, J.R, Pau, M.G, Sullivan, N.J, Goudsmit, J, Nabel, G.J, Graham, B.S

Volltext

Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV‐1 human monoclonal antibody VRC01 in healthy adults von Ledgerwood, J. E., Coates, E. E., Yamshchikov, G., Saunders, J. G., Holman, L., Enama, M. E., DeZure, A., Lynch, R. M., Gordon, I., Plummer, S., Hendel, C. S., Pegu, A., Conan‐Cibotti, M., Sitar, S., Bailer, R. T., Narpala, S., McDermott, A., Louder, M., O'Dell, S., Mohan, S., Pandey, J. P., Schwartz, R. M., Hu, Z., Koup, R. A., Capparelli, E., Mascola, J. R., Graham, B. S.

Volltext

Influenza Virus H5 DNA Vaccination Is Immunogenic by Intramuscular and Intradermal Routes in Humans von Ledgerwood, J E, Hu, Z, Gordon, I J, Yamshchikov, G, Enama, M E, Plummer, S, Bailer, R, Pearce, M B, Tumpey, T M, Koup, R A, Mascola, J R, Nabel, G J, Graham, B S

Volltext

Isolation of broadly neutralizing HIV-1 antibodies from high-throughput single B cell culture von Longo, NS, Doria-Rose, N, McKee, K, O'Dell, S, Louder, MK, Yang, Z, Bailer, R, Mascola, JR

Volltext

Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV‐1 Candidate Vaccine Delivered by a Replication‐Defective Recombinant Adenovirus Vector von Catanzaro, Andrew T. , Koup, Richard A. , Roederer, Mario , Bailer, Robert T. , Enama, Mary E. , Moodie, Zoe , Gu, Lin , Martin, Julie E. , Novik, Laura , Chakrabarti, Bimal K. , Butman, Bryan T. , Gall, Jason G. D. , King, C. Richter , Andrews, Charla A. , Sheets, Rebecca , Gomez, Phillip L. , Mascola, John R. , Nabel, Gary J. 

Volltext

P14-10. Comparable immunogenicity of VRC DNA and rAd5 HIV-1 vaccines delivered by intramuscular, subcutaneous and intradermal routes in healthy adults (VRC 011) von Ledgerwood, JE, Novik, L, Enama, ME, Gordon, I J, Holman, LA, Nason, M C, Bailer, R T, Roederer, M, Koup, R A, Mascola, J R, Nabel, G J, Graham, B S

Volltext

In vivo targeting of HIV gag to dendritic cells in combination with poly ICLC is safe and immunogenic in healthy volunteers von Caskey, M, Trumpfheller, C, Pollak, S, Sinnenberg, L, Hurley, A, Pring, J, Shimeliovich, I, Yipp, B, Anandasabapathy, N, Mehandru, S, Sarma, P, Koup, R, Bailer, R, Tomaras, G, Sato, A, Keler, T, Steinman, R, Schlesinger, S

Volltext

Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV‐1 DNA Candidate Vaccine von Graham, Barney S. , Koup, Richard A. , Roederer, Mario , Bailer, Robert T. , Enama, Mary E. , Moodie, Zoe , Martin, Julie E. , McCluskey, Margaret M. , Chakrabarti, Bimal K. , Lamoreaux, Laurie , Andrews, Charla A. , Gomez, Phillip L. , Mascola, John R. 

Volltext

P18-06. Increased HIV-specific immunity in HIV-infected individuals vaccinated with a DNA prime, rAd5 boost regimen von Casazza, J P, Bowman, K, Adzaku, S, Ambrozak, DA, Roederer, M, Bailer, R T, Enama, M, Nason, M, Ledgerwood, JE, Graham, B S, Koup, R A

Volltext

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability von Dubrovskaya, Viktoriya, Tran, Karen, Ozorowski, Gabriel, Guenaga, Javier, Wilson, Richard, Bale, Shridhar, Cottrell, Christopher A., Turner, Hannah L., Seabright, Gemma, O’Dell, Sijy, Torres, Jonathan L., Yang, Lifei, Feng, Yu, Leaman, Daniel P., Vázquez Bernat, Néstor, Liban, Tyler, Louder, Mark, McKee, Krisha, Bailer, Robert T., Movsesyan, Arlette, Doria-Rose, Nicole A., Pancera, Marie, Karlsson Hedestam, Gunilla B., Zwick, Michael B., Crispin, Max, Mascola, John R., Ward, Andrew B., Wyatt, Richard T.

Volltext

Inhibition of IL-12 Production in Human Monocyte-Derived Macrophages by TNF von Ma, Xiaojing, Sun, Junwei, Papasavvas, Emmanouil, Riemann, Helge, Robertson, Susan, Marshall, Jason, Bailer, Robert T, Moore, Anne, Donnelly, Raymond P, Trinchieri, Giorgio, Montaner, Luis J

Volltext

P16-19. Statistical design and analysis of the CAVD-VIMC Elispot transfer study 001 von Huang, Y, Sato, A, Wood, B, Gill, D, Kochar, N, Tarragona, T, Sambor, A, Wan, H, Levine, G, Self, S, Koup, R, Cox, J, Bailer, R, Gilmour, J

Volltext

Long-lived memory T lymphocyte responses against SARS coronavirus nucleocapsid protein in SARS-recovered patients von Peng, Hui, Yang, Li-tao, Wang, Ling-yun, Li, Jian, Huang, Jun, Lu, Zhi-qiang, Koup, Richard A., Bailer, Robert T., Wu, Chang-you

Volltext

IL-13 acts on macrophages to block the completion of reverse transcription, inhibit virus production, and reduce virus infectivity von Montaner, Luis J., Bailer, Robert T., Gordon, Siamon

Volltext

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization von Kong, Rui, Duan, Hongying, Sheng, Zizhang, Xu, Kai, Acharya, Priyamvada, Chen, Xuejun, Cheng, Cheng, Dingens, Adam S., Gorman, Jason, Sastry, Mallika, Shen, Chen-Hsiang, Zhang, Baoshan, Zhou, Tongqing, Chuang, Gwo-Yu, Chao, Cara W., Gu, Ying, Jafari, Alexander J., Louder, Mark K., O’Dell, Sijy, Rowshan, Ariana P., Viox, Elise G., Wang, Yiran, Choi, Chang W., Corcoran, Martin M., Corrigan, Angela R., Dandey, Venkata P., Eng, Edward T., Geng, Hui, Foulds, Kathryn E., Guo, Yicheng, Kwon, Young D., Lin, Bob, Liu, Kevin, Mason, Rosemarie D., Nason, Martha C., Ohr, Tiffany Y., Ou, Li, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Todd, John P., Wang, Shuishu, Wei, Hui, Wu, Winston, Mullikin, James C., Bailer, Robert T., Doria-Rose, Nicole A., Karlsson Hedestam, Gunilla B., Scorpio, Diana G., Overbaugh, Julie, Bloom, Jesse D., Carragher, Bridget, Potter, Clinton S., Shapiro, Lawrence, Kwong, Peter D., Mascola, John R.

Volltext

IL‐13 and TNF‐α  inhibit dual‐tropic HIV‐1 in primary macrophages by reduction of surface expression of CD4, chemokine receptors CCR5, CXCR4 and post‐entry viral gene expression... von Bailer, Robert T., Lee, Benhur, Montaner, Luis J.

Volltext

IL-13 and IFN-gamma secretion by activated T cells in HIV-1 infection associated with viral suppression and a lack of disease progression von Bailer, R T, Holloway, A, Sun, J, Margolick, J B, Martin, M, Kostman, J, Montaner, L J

Volltext

Long-lived effector/central memory T-cell responses to severe acute respiratory syndrome coronavirus (SARS-CoV) S antigen in recovered SARS patients von Yang, Li-Tao, Peng, Hui, Zhu, Zhao-Ling, Li, Gang, Huang, Zi-Tong, Zhao, Zhi-Xin, Koup, Richard A., Bailer, Robert T., Wu, Chang-You

Volltext

CCR5 and CXCR4 expression correlated with X4 and R5 HIV-1 infection yet not sustained replication in Th1 and Th2 cells von MOONIS, Mona, LEE, Benhur, BAILER, Robert T, QI LUO, MONTANER, Luis J

Volltext