Organs-on-chips at the frontiers of drug discovery von Esch, Eric W., Bahinski, Anthony, Huh, Dongeun

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Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro von Villenave, Remi, Wales, Samantha Q, Hamkins-Indik, Tiama, Papafragkou, Efstathia, Weaver, James C, Ferrante, Thomas C, Bahinski, Anthony, Elkins, Christopher A, Kulka, Michael, Ingber, Donald E

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Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip von Benam, Kambez H., Novak, Richard, Nawroth, Janna, Hirano-Kobayashi, Mariko, Ferrante, Thomas C., Choe, Youngjae, Prantil-Baun, Rachelle, Weaver, James C., Bahinski, Anthony, Parker, Kevin K., Ingber, Donald E.

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Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes von Saleem, Umber, van Meer, Berend J, Katili, Puspita A, Mohd Yusof, Nurul A N, Mannhardt, Ingra, Garcia, Ana Krotenberg, Tertoolen, Leon, de Korte, Tessa, Vlaming, Maria L H, McGlynn, Karen, Nebel, Jessica, Bahinski, Anthony, Harris, Kate, Rossman, Eric, Xu, Xiaoping, Burton, Francis L, Smith, Godfrey L, Clements, Peter, Mummery, Christine L, Eschenhagen, Thomas, Hansen, Arne, Denning, Chris

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Clear castable polyurethane elastomer for fabrication of microfluidic devices von Domansky, Karel, Leslie, Daniel C, McKinney, James, Fraser, Jacob P, Sliz, Josiah D, Hamkins-Indik, Tiama, Hamilton, Geraldine A, Bahinski, Anthony, Ingber, Donald E

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CardioMotion: identification of functional and structural cardiotoxic liabilities in small molecules through brightfield kinetic imaging von Stebbeds, William, Raniga, Kavita, Standing, David, Wallace, Iona, Bayliss, James, Brown, Andrew, Kasprowicz, Richard, Dalmas Wilk, Deidre, Deakyne, Julianna, Clements, Peter, Chaudhary, Khuram W, Rossman, Eric I, Bahinski, Anthony, Francis, Jo

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Cardiac sodium channel inhibition by lamotrigine: In vitro characterization and clinical implications von Ingleby‐Talecki, Lindsey, Dijkman, Sven C., Oosterholt, Sean P., Della Pasqua, Oscar, Winter, Christina, Cunnington, Marianne, Rebar, Linda, Forero‐Schwanhaeuser, Sergio, Patel, Vickas, Cooper, James A., Bahinski, Anthony, Chaudhary, Khuram W.

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HL-1 Cells: A Cardiac Muscle Cell Line that Contracts and Retains Phenotypic Characteristics of the Adult Cardiomyocyte von Claycomb, William C., Lanson, Nicholas A., Stallworth, Beverly S., Egeland, Daniel B., Delcarpio, Joseph B., Bahinski, Anthony, Izzo, Nicholas J.

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Ca2+-Independent Alterations in Diastolic Sarcomere Length and Relaxation Kinetics in a Mouse Model of Lipotoxic Diabetic Cardiomyopathy von Flagg, Thomas P, Cazorla, Olivier, Remedi, Maria S, Haim, Todd E, Tones, Michael A, Bahinski, Anthony, Numann, Randal E, Kovacs, Attila, Schaffer, Jean E, Nichols, Colin G, Nerbonne, Jeanne M

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Microfabrication of human organs-on-chips von Huh, Dongeun, Kim, Hyun Jung, Fraser, Jacob P, Shea, Daniel E, Khan, Mohammed, Bahinski, Anthony, Hamilton, Geraldine A, Ingber, Donald E

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Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro von Benam, Kambez H, Villenave, Remi, Lucchesi, Carolina, Varone, Antonio, Hubeau, Cedric, Lee, Hyun-Hee, Alves, Stephen E, Salmon, Michael, Ferrante, Thomas C, Weaver, James C, Bahinski, Anthony, Hamilton, Geraldine A, Ingber, Donald E

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Comparison of automated analysis methods for small animal activity assessment von Wu, XueJun, Payseur, Jason, Turner, Sandra, Bahinski, Anthony, Rossman, Eric

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Evaluation of a left ventricular pressure catheterized rat telemetry model to measure cardiac contractility: Prevalence of post-surgical arrhythmias von Turner, Sandra, Payseur, Jason, Wu, XueJun, Rossman, Eric, Bahinski, Anthony

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Robotic fluidic coupling and interrogation of multiple vascularized organ chips von Novak, Richard, Ingram, Miles, Marquez, Susan, Das, Debarun, Delahanty, Aaron, Herland, Anna, Maoz, Ben M., Jeanty, Sauveur S. F., Somayaji, Mahadevabharath R., Burt, Morgan, Calamari, Elizabeth, Chalkiadaki, Angeliki, Cho, Alexander, Choe, Youngjae, Chou, David Benson, Cronce, Michael, Dauth, Stephanie, Divic, Toni, Fernandez-Alcon, Jose, Ferrante, Thomas, Ferrier, John, FitzGerald, Edward A., Fleming, Rachel, Jalili-Firoozinezhad, Sasan, Grevesse, Thomas, Goss, Josue A., Hamkins-Indik, Tiama, Henry, Olivier, Hinojosa, Chris, Huffstater, Tessa, Jang, Kyung-Jin, Kujala, Ville, Leng, Lian, Mannix, Robert, Milton, Yuka, Nawroth, Janna, Nestor, Bret A., Ng, Carlos F., O’Connor, Blakely, Park, Tae-Eun, Sanchez, Henry, Sliz, Josiah, Sontheimer-Phelps, Alexandra, Swenor, Ben, Thompson, Guy, Touloumes, George J., Tranchemontagne, Zachary, Wen, Norman, Yadid, Moran, Bahinski, Anthony, Hamilton, Geraldine A., Levner, Daniel, Levy, Oren, Przekwas, Andrzej, Prantil-Baun, Rachelle, Parker, Kevin K., Ingber, Donald E.

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Effect of compound plate composition on measurement of hERG current IC50 using PatchXpress von Mo, Zun-Li, Faxel, Tracy, Yang, Young-Sun, Gallavan, Robert, Messing, Dean, Bahinski, Anthony

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Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device von Kim, Hyun Jung, Lee, Jaewon, Choi, Jin-Ha, Bahinski, Anthony, Ingber, Donald E

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Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective von Vargas, Hugo M., Rolf, Michael G., Wisialowski, Todd A., Achanzar, William, Bahinski, Anthony, Bass, Alan, Benson, Charles T, Chaudhary, Khuram W., Couvreur, Nicolas, Dota, Corina, Engwall, Michael J, Michael Foley, C., Gallacher, David, Greiter‐Wilke, Andrea, Guillon, Jean‐Michel, Guth, Brian, Himmel, Herbert M., Hegele‐Hartung, Christa, Ito, Maki, Jenkinson, Stephen, Chiba, Katsuyoshi, Lagrutta, Armando, Levesque, Paul, Martel, Eric, Okai, Yoshiko, Peri, Ravikumar, Pointon, Amy, Qu, Yusheng, Teisman, Ard, Traebert, Martin, Yoshinaga, Takashi, Gintant, Gary A., Leishman, Derek J., Valentin, Jean‐Pierre

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Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing von Marx, Uwe

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Investigating the effects of mitochondrial inhibitors and uncoupler on hiPSC-CM MEA assay to predict drug-induced cardiotoxicity von Wang, Shuya, Cato, Matthew J., Valentine, Patricia A., Purohit, Prasad G., Bahinski, Anthony, Chaudhary, Khuram W.

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Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip von Torisawa, Yu-suke, Mammoto, Tadanori, Jiang, Elisabeth, Jiang, Amanda, Mammoto, Akiko, Watters, Alexander L., Bahinski, Anthony, Ingber, Donald E.

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