Expression and function of epithelial cell adhesion molecule EpCAM: where are we after 40 years? von Gires, Olivier, Pan, Min, Schinke, Henrik, Canis, Martin, Baeuerle, Patrick A.

Volltext

The Emerging Role of EpCAM in Cancer and Stem Cell Signaling von MUNZ, Markus, BAEUERLE, Patrick A, GIRES, Olivier

Volltext

Bispecific T cell engager (BiTE®) antibody constructs can mediate bystander tumor cell killing von Ross, Sandra L, Sherman, Marika, McElroy, Patricia L, Lofgren, Julie A, Moody, Gordon, Baeuerle, Patrick A, Coxon, Angela, Arvedson, Tara

Volltext

Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response von Baeuerle, Patrick A., Ding, Jian, Patel, Ekta, Thorausch, Niko, Horton, Holly, Gierut, Jessica, Scarfo, Irene, Choudhary, Rashmi, Kiner, Olga, Krishnamurthy, Janani, Le, Bonnie, Morath, Anna, Baldeviano, G. Christian, Quinn, Justin, Tavares, Patrick, Wei, Qi, Weiler, Solly, Maus, Marcela V., Getts, Daniel, Schamel, Wolfgang W., Hofmeister, Robert

Volltext

Engaging natural killer cells for cancer therapy via NKG2D, CD16A and other receptors von Whalen, Kerry A., Rakhra, Kavya, Mehta, Naveen K., Steinle, Alexander, Michaelson, Jennifer S., Baeuerle, Patrick A.

Volltext

On the abundance of EpCAM on cancer stem cells von Gires, Olivier, Klein, Christoph A, Baeuerle, Patrick A

Volltext

Intratumoral injection and retention hold promise to improve cytokine therapies for cancer von Sauer, Karsten, Rakhra, Kavya, Wu, Kaida, Mehta, Naveen K, Michaelson, Jennifer S, Baeuerle, Patrick A

Volltext

Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumors von Ding, Jian, Guyette, Sarah, Schrand, Brett, Geirut, Jessica, Horton, Holly, Guo, Guangwu, Delgoffe, Greg, Menk, Ashley, Baeuerle, Patrick A., Hofmeister, Robert, Tighe, Robert

Volltext

Bispecific T-Cell Engaging Antibodies for Cancer Therapy von BAEUERLE, Patrick A, REINHARDT, Carsten

Volltext

T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells von Lutterbuese, Ralf, Raum, Tobias, Kischel, Roman, Hoffmann, Patrick, Mangold, Susanne, Rattel, Benno, Friedrich, Matthias, Thomas, Oliver, Lorenczewski, Grit, Rau, Doris, Schaller, Evelyne, Herrmann, Ines, Wolf, Andreas, Urbig, Thomas, Baeuerle, Patrick A., Kufer, Peter, Ravetch, Jeffrey V.

Volltext

Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110 von Deisting, Wibke, Raum, Tobias, Kufer, Peter, Baeuerle, Patrick A, Münz, Markus

Volltext

Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells von Herrmann, Ines, Baeuerle, Patrick A, Friedrich, Matthias, Murr, Alexander, Filusch, Susanne, Rüttinger, Dominik, Majdoub, Mariam W, Sharma, Sherven, Kufer, Peter, Raum, Tobias, Münz, Markus

Volltext

Blinatumomab: a historical perspective von Nagorsen, Dirk, Kufer, Peter, Baeuerle, Patrick A, Bargou, Ralf

Volltext

Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab von Nagorsen, Dirk, Baeuerle, Patrick A.

Volltext

A novel IgG-based FLT3xCD3 bispecific antibody for the treatment of AML and B-ALL von Mehta, Naveen K, Pfluegler, Martin, Meetze, Kristan, Li, Bochong, Sindel, Isabelle, Vogt, Fabian, Marklin, Melanie, Heitmann, Jonas S, Kauer, Joseph, Osburg, Lukas, Zekri, Latifa, Bühring, Hans-Jörg, Mueller, Stefanie, Hörner, Sebastian, Baeuerle, Patrick A, Michaelson, Jennifer S, Jung, Gundram, Salih, Helmut R

Volltext

Changes in clinical laboratory parameters and pharmacodynamic markers in response to blinatumomab treatment of patients with relapsed/refractory ALL von Nägele, Virginie, Kratzer, Andrea, Zugmaier, Gerhard, Holland, Chris, Hijazi, Youssef, Topp, Max S, Gökbuget, Nicola, Baeuerle, Patrick A, Kufer, Peter, Wolf, Andreas, Klinger, Matthias

Volltext

Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies von Münz, Markus, Murr, Alexander, Kvesic, Majk, Rau, Doris, Mangold, Susanne, Pflanz, Stefan, Lumsden, John, Volkland, Jörg, Fagerberg, Jan, Riethmüller, Gert, Rüttinger, Dominik, Kufer, Peter, Baeuerle, Patrick A, Raum, Tobias

Volltext

Targeting T cells to tumor cells using bispecific antibodies von Frankel, Stanley R, Baeuerle, Patrick A

Volltext

CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression von Meetze, Kristan, Mehta, Naveen K, Li, Bochong, Findlay, Hannah M, London, Timothy B, Patakas, Agapitos, Michaelson, Jennifer S, Baeuerle, Patrick A

Volltext

CD19-directed T cell-engaging antibodies for the treatment of autoimmune disease von Michaelson, Jennifer S, Baeuerle, Patrick A

Volltext