Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function von Meulebrouck, Sarah, Merrheim, Judith, Queniat, Gurvan, Bourouh, Cyril, Derhourhi, Mehdi, Boissel, Mathilde, Yi, Xiaoyan, Badreddine, Alaa, Boutry, Raphaël, Leloire, Audrey, Toussaint, Bénédicte, Amanzougarene, Souhila, Vaillant, Emmanuel, Durand, Emmanuelle, Loiselle, Hélène, Huyvaert, Marlène, Dechaume, Aurélie, Scherrer, Victoria, Marchetti, Piero, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Roussel, Ronan, Scharfmann, Raphaël, Cnop, Miriam, Canouil, Mickaël, Baron, Morgane, Froguel, Philippe, Bonnefond, Amélie

Volltext

Compound genetic etiology in a patient with a syndrome including diabetes, intellectual deficiency and distichiasis von Le Collen, Lauriane, Delemer, Brigitte, Spodenkiewicz, Marta, Cornillet Lefebvre, Pascale, Durand, Emmanuelle, Vaillant, Emmanuel, Badreddine, Alaa, Derhourhi, Mehdi, Mouhoub, Tarik Ait, Jouret, Guillaume, Juttet, Pauline, Souchon, Pierre François, Vaxillaire, Martine, Froguel, Philippe, Bonnefond, Amélie, Doco Fenzy, Martine

Volltext

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming von Oger, Frédérik, Moreno, Maeva, Derhourhi, Mehdi, Thiroux, Bryan, Berberian, Lionel, Bourouh, Cyril, Durand, Emmanuelle, Amanzougarene, Souhila, Badreddine, Alaa, Blanc, Etienne, Molendi-Coste, Olivier, Pineau, Laurent, Pasquetti, Gianni, Rolland, Laure, Carney, Charlène, Bornaque, Florine, Courty, Emilie, Gheeraert, Céline, Eeckhoute, Jérôme, Dombrowicz, David, Kerr-Conte, Julie, Pattou, François, Staels, Bart, Froguel, Philippe, Bonnefond, Amélie, Annicotte, Jean-Sébastien

Volltext

Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan von Saeed, Sadia, Janjua, Qasim M, Haseeb, Attiya, Khanam, Roohia, Durand, Emmanuelle, Vaillant, Emmanuel, Ning, Lijiao, Badreddine, Alaa, Berberian, Lionel, Boissel, Mathilde, Amanzougarene, Souhila, Canouil, Mickaël, Derhourhi, Mehdi, Bonnefond, Amélie, Arslan, Muhammad, Froguel, Philippe

Volltext

Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence in an Inbred Population of Pakistan von Saeed, Sadia, Arslan, Muhammad, Manzoor, Jaida, Din, Sadia M., Janjua, Qasim M., Ayesha, Hina, Ain, Qura-tul, Inam, Laraib, Lobbens, Stephane, Vaillant, Emmanuel, Durand, Emmanuelle, Derhourhi, Mehdi, Amanzougarene, Souhila, Badreddine, Alaa, Berberian, Lionel, Gaget, Stefan, Khan, Waqas I., Butt, Taeed A., Bonnefond, Amelie, Froguel, Philippe

Volltext

Biallelic Mutations in P4HTM Cause Syndromic Obesity von Saeed, Sadia, Ning, Lijiao, Badreddine, Alaa, Mirza, Muhammad Usman, Boissel, Mathilde, Khanam, Roohia, Manzoor, Jaida, Janjua, Qasim M, Khan, Waqas I, Toussaint, Bénédicte, Vaillant, Emmanuel, Amanzougarene, Souhila, Derhourhi, Mehdi, Trant, John F, Siegert, Anna-Maria, Lam, Brian Y H, Yeo, Giles S H, Chabraoui, Layachi, Touzani, Asmae, Kulkarni, Abhishek, Farooqi, I Sadaf, Bonnefond, Amélie, Arslan, Muhammad, Froguel, Philippe

Volltext

Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study von Folon, Lise, Baron, Morgane, Toussaint, Bénédicte, Vaillant, Emmanuel, Boissel, Mathilde, Scherrer, Victoria, Loiselle, Hélène, Leloire, Audrey, Badreddine, Alaa, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Aboulouard, Soulaimane, Salzet, Michel, Canouil, Mickaël, Derhourhi, Mehdi, Froguel, Philippe, Bonnefond, Amélie

Volltext

Heterozygous pathogenic variants in POMC are not responsible for monogenic obesity: Implication for MC4R agonist use von Le Collen, Lauriane, Delemer, Brigitte, Poitou, Christine, Vaxillaire, Martine, Toussaint, Bénédicte, Dechaume, Aurélie, Badreddine, Alaa, Boissel, Mathilde, Derhourhi, Mehdi, Clément, Karine, Petit, Jean M., Mau-Them, Frédéric Tran, Bruel, Ange-Line, Thauvin-Robinet, Christel, Saveanu, Alexandru, Cherifi, Blandine Gatta, Le Beyec-Le Bihan, Johanne, Froguel, Philippe, Bonnefond, Amélie

Volltext

Compound genetic etiology in a patient with a syndrome including diabetes, intellectual deficiency and distichiasis von Le Collen, Lauriane, Delemer, Brigitte, Spodenkiewicz, Marta, Cornillet Lefebvre, Pascale, Durand, Emmanuelle, Vaillant, Emmanuel, Badreddine, Alaa, Derhourhi, Mehdi, Mouhoub, Tarik Ait, Jouret, Guillaume, Juttet, Pauline, Souchon, Pierre François, Vaxillaire, Martine, Froguel, Philippe, Bonnefond, Amélie, Doco Fenzy, Martine

Volltext

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming von Oger, Frédérik, Moreno, Maeva, Derhourhi, Mehdi, Thiroux, Bryan, Berberian, Lionel, Bourouh, Cyril, Durand, Emmanuelle, Amanzougarene, Souhila, Badreddine, Alaa, Blanc, Etienne, Molendi-Coste, Olivier, Pineau, Laurent, Pasquetti, Gianni, Rolland, Laure, Carney, Charlène, Bornaque, Florine, Courty, Emilie, Gheeraert, Céline, Eeckhoute, Jérôme, Dombrowicz, David, Kerr-Conte, Julie, Pattou, François, Staels, Bart, Froguel, Philippe, Bonnefond, Amélie, Annicotte, Jean-Sébastien

Volltext

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming von Oger, Frédérik, Moreno, Maeva, Derhourhi, Mehdi, Thiroux, Bryan, Berberian, Lionel, Bourouh, Cyril, Durand, Emmanuelle, Amanzougarene, Souhila, Badreddine, Alaa, Blanc, Etienne, Molendi-Coste, Olivier, Pineau, Laurent, Pasquetti, Gianni, Rolland, Laure, Carney, Charlène, Bornaque, Florine, Courty, Emilie, Gheeraert, Céline, Eeckhoute, Jérôme, Dombrowicz, David, Kerr-Conte, Julie, Pattou, François, Staels, Bart, Froguel, Philippe, Bonnefond, Amélie, Annicotte, Jean-Sébastien

Volltext