Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism von Peters, G.J, Backus, H.H.J, Freemantle, S, van Triest, B, Codacci-Pisanelli, G, van der Wilt, C.L, Smid, K, Lunec, J, Calvert, A.H, Marsh, S, McLeod, H.L, Bloemena, E, Meijer, S, Jansen, G, van Groeningen, C.J, Pinedo, H.M

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Thymidylate synthase inhibition triggers apoptosis via caspases-8 and -9 in both wild-type and mutant p53 colon cancer cell lines von Backus, H.H.J, Wouters, D, Ferreira, C.G, van Houten, V.M.M, Brakenhoff, R.H, Pinedo, H.M, Peters, G.J

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Folate depletion increases sensitivity of solid tumor cell lines to 5‐fluorouracil and antifolates von Backus, H.H.J., Pinedo, H.M., Wouters, D., Padrón, J.M., Molders, N., van der Wilt, C.L., van Groeningen, C.J., Jansen, G., Peters, G.J.

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Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate syntha... von Peters, G.J, van Triest, B, Backus, H.H.J, Kuiper, C.M, van der Wilt, C.L, Pinedo, H.M

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Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases von Backus, H H J, Van Groeningen, C J, Vos, W, Dukers, D F, Bloemena, E, Wouters, D, Pinedo, H M, Peters, G J

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Rb, mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer von Backus, H. H. J., van Riel, J. M. G. H., van Groeningen, C. J., Vos, W., Dukers, D. F., Bloemena, E., Wouters, D., Pinedo, H. M., Peters, G. J.

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5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients von Backus, H. H. J., Dukers, D. F., van Groeningen, C. J., Vos, W., Bloemena, E., Wouters, D., van Reil, J. M. G. H., Smid, K., Giaccone, G., Pinedo, H. M., Peters, G. J.

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