Polyamine synthesis as a target of MYC oncogenes von Bachmann, André S., Geerts, Dirk

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Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells von Schultz, Chad R, Gruhlke, Martin C. H, Slusarenko, Alan J, Bachmann, André S

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plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism von Groll, Michael, Schellenberg, Barbara, Bachmann, André S, Archer, Crystal R, Huber, Robert, Powell, Tracy K, Lindow, Steven, Kaiser, Markus, Dudler, Robert

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Anti-tumor effect of sulfasalazine in neuroblastoma von Mooney, Marie R., Geerts, Dirk, Kort, Eric J., Bachmann, André S.

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A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma von Saulnier Sholler, Giselle L, Gerner, Eugene W, Bergendahl, Genevieve, MacArthur, Robert B, VanderWerff, Alyssa, Ashikaga, Takamaru, Bond, Jeffrey P, Ferguson, William, Roberts, William, Wada, Randal K, Eslin, Don, Kraveka, Jacqueline M, Kaplan, Joel, Mitchell, Deanna, Parikh, Nehal S, Neville, Kathleen, Sender, Leonard, Higgins, Timothy, Kawakita, Masao, Hiramatsu, Kyoko, Moriya, Shun-Suke, Bachmann, André S

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AMXT‐1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transp... von Samal, Katherine, Zhao, Ping, Kendzicky, Ann, Yco, Lisette P., McClung, Heather, Gerner, Eugene, Burns, Mark, Bachmann, André S., Sholler, Giselle

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Bachmann–Bupp syndrome and treatment von Bachmann, André S., VanSickle, Elizabeth A., Michael, Julianne, Vipond, Marlie, Bupp, Caleb P.

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Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation von Schultz, Chad R, Bupp, Caleb P, Rajasekaran, Surender, Bachmann, André S

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Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma von Uhl, Katie L, Schultz, Chad R, Geerts, Dirk, Bachmann, André S

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Ornithine decarboxylase as a therapeutic target for endometrial cancer von Kim, Hong Im, Schultz, Chad R, Buras, Andrea L, Friedman, Elizabeth, Fedorko, Alyssa, Seamon, Leigh, Chandramouli, Gadisetti V R, Maxwell, G Larry, Bachmann, André S, Risinger, John I

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Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma von Schultz, Chad R., Swanson, Matthew A., Dowling, Thomas C., Bachmann, André S.

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Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features von Bupp, Caleb P., Schultz, Chad R., Uhl, Katie L., Rajasekaran, Surender, Bachmann, André S.

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Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease von Rajasekaran, Surender, Bupp, Caleb P., Leimanis-Laurens, Mara, Shukla, Ankit, Russell, Christopher, Junewick, Joseph, Gleason, Emily, VanSickle, Elizabeth A., Edgerly, Yvonne, Wittmann, Bryan M., Prokop, Jeremy W., Bachmann, Andre S.

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Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma von Mills, Catherine M., Turner, Jonathan, Piña, Ivett C., Garrabrant, Kathleen A., Geerts, Dirk, Bachmann, André S., Peterson, Yuri K., Woster, Patrick M.

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Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition von Clerc, Jérôme, Groll, Michael, Illich, Damir J, Bachmann, André S, Huber, Robert, Schellenberg, Barbara, Dudler, Robert, Kaiser, Markus

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Expanding the phenotype: Four new cases and hope for treatment in Bachmann‐Bupp syndrome von VanSickle, Elizabeth A., Michael, Julianne, Bachmann, André S., Rajasekaran, Surender, Prokop, Jeremy W., Kuzniecky, Ruben, Hofstede, Floris C., Steindl, Katharina, Rauch, Anita, Lipson, Mark H., Bupp, Caleb P.

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Novel Interaction of Ornithine Decarboxylase with Sepiapterin Reductase Regulates Neuroblastoma Cell Proliferation von Lange, Ingo, Geerts, Dirk, Feith, David J., Mocz, Gabor, Koster, Jan, Bachmann, André S.

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Syrbactin proteasome inhibitor TIR-199 overcomes bortezomib chemoresistance and inhibits multiple myeloma tumor growth in vivo von Pierce, Marquicia R., Robinson, Reeder M., Ibarra-Rivera, Tannya R., Pirrung, Michael C., Dolloff, Nathan G., Bachmann, André S.

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Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation von Benton, Thomas Z, Mills, Catherine M, Turner, Jonathan M, Francis, Megan J, Solomon, Dalan J, Burger, Pieter B, Peterson, Yuri K, Dolloff, Nathan G, Bachmann, André S, Woster, Patrick M

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Gene expression signatures identify paediatric patients with multiple organ dysfunction who require advanced life support in the intensive care unit von Shankar, Rama, Leimanis, Mara L., Newbury, Patrick A., Liu, Ke, Xing, Jing, Nedveck, Derek, Kort, Eric J., Prokop, Jeremy W, Zhou, Guoli, Bachmann, André S, Chen, Bin, Rajasekaran, Surender

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