The molecular details of cytokine signaling via the JAK/STAT pathway von Morris, Rhiannon, Kershaw, Nadia J., Babon, Jeffrey J.

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Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity von Babon, Jeffrey J., Kershaw, Nadia J., Murphy, James M., Varghese, Leila N., Laktyushin, Artem, Young, Samuel N., Lucet, Isabelle S., Norton, Raymond S., Nicola, Nicos A.

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The molecular regulation of Janus kinase (JAK) activation von Babon, Jeffrey J, Lucet, Isabelle S, Murphy, James M, Nicola, Nicos A, Varghese, Leila N

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The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism von Murphy, James M., Czabotar, Peter E., Hildebrand, Joanne M., Lucet, Isabelle S., Zhang, Jian-Guo, Alvarez-Diaz, Silvia, Lewis, Rowena, Lalaoui, Najoua, Metcalf, Donald, Webb, Andrew I., Young, Samuel N., Varghese, Leila N., Tannahill, Gillian M., Hatchell, Esme C., Majewski, Ian J., Okamoto, Toru, Dobson, Renwick C.J., Hilton, Douglas J., Babon, Jeffrey J., Nicola, Nicos A., Strasser, Andreas, Silke, John, Alexander, Warren S.

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The molecular basis of JAK/STAT inhibition by SOCS1 von Liau, Nicholas P. D., Laktyushin, Artem, Lucet, Isabelle S., Murphy, James M., Yao, Shenggen, Whitlock, Eden, Callaghan, Kimberley, Nicola, Nicos A., Kershaw, Nadia J., Babon, Jeffrey J.

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Inhibition of IL-6 family cytokines by SOCS3 von Babon, Jeffrey J, Varghese, Leila N, Nicola, Nicos A

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death von Hildebrand, Joanne M., Tanzer, Maria C., Lucet, Isabelle S., Young, Samuel N., Spall, Sukhdeep K., Sharma, Pooja, Pierotti, Catia, Garnier, Jean-Marc, Dobson, Renwick C.J., Webb, Andrew I., Tripaydonis, Anne, Babon, Jeffrey J., Mulcair, Mark D., Scanlon, Martin J., Alexander, Warren S., Wilks, Andrew F., Czabotar, Peter E., Lessene, Guillaume, Murphy, James M., Silke, John

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NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS von Louis, Cynthia, Souza-Fonseca-Guimaraes, Fernando, Yang, Yuyan, D'Silva, Damian, Kratina, Tobias, Dagley, Laura, Hediyeh-Zadeh, Soroor, Rautela, Jai, Masters, Seth Lucian, Davis, Melissa J, Babon, Jeffrey J, Ciric, Bogoljub, Vivier, Eric, Alexander, Warren S, Huntington, Nicholas D, Wicks, Ian P

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Suppression of cytokine signaling: The SOCS perspective von Linossi, Edmond M, Babon, Jeffrey J, Hilton, Douglas J, Nicholson, Sandra E

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity von Liang, Shuwei, Tran, Eric, Du, Xin, Dong, Jiajun, Sudholz, Harrison, Chen, Hao, Qu, Zihan, Huntington, Nicholas D., Babon, Jeffrey J., Kershaw, Nadia J., Zhang, Zhong-Yin, Baell, Jonathan B., Wiede, Florian, Tiganis, Tony

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Persistence of myelofibrosis treated with ruxolitinib: biology and clinical implications von Ross, David M, Babon, Jeffrey J, Tvorogov, Denis, Thomas, Daniel

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SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition von Kershaw, Nadia J, Murphy, James M, Liau, Nicholas P D, Varghese, Leila N, Laktyushin, Artem, Whitlock, Eden L, Lucet, Isabelle S, Nicola, Nicos A, Babon, Jeffrey J

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A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties von Murphy, James M, Zhang, Qingwei, Young, Samuel N, Reese, Michael L, Bailey, Fiona P, Eyers, Patrick A, Ungureanu, Daniela, Hammaren, Henrik, Silvennoinen, Olli, Varghese, Leila N, Chen, Kelan, Tripaydonis, Anne, Jura, Natalia, Fukuda, Koichi, Qin, Jun, Nimchuk, Zachary, Mudgett, Mary Beth, Elowe, Sabine, Gee, Christine L, Liu, Ling, Daly, Roger J, Manning, Gerard, Babon, Jeffrey J, Lucet, Isabelle S

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Small molecule drug discovery targeting the JAK-STAT pathway von Lv, You, Mi, Pengbing, Babon, Jeffrey J., Fan, Guohuang, Qi, Jianxun, Cao, Longxing, Lang, Jiajia, Zhang, Jin, Wang, Faming, Kobe, Bostjan

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Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus von Jiang, Simon H., Athanasopoulos, Vicki, Ellyard, Julia I., Chuah, Aaron, Cappello, Jean, Cook, Amelia, Prabhu, Savit B., Cardenas, Jacob, Gu, Jinghua, Stanley, Maurice, Roco, Jonathan A., Papa, Ilenia, Yabas, Mehmet, Walters, Giles D., Burgio, Gaetan, McKeon, Kathryn, Byers, James M., Burrin, Charlotte, Enders, Anselm, Miosge, Lisa A., Canete, Pablo F., Jelusic, Marija, Tasic, Velibor, Lungu, Adrian C., Alexander, Stephen I., Kitching, Arthur R., Fulcher, David A., Shen, Nan, Arsov, Todor, Gatenby, Paul A., Babon, Jeff J., Mallon, Dominic F., de Lucas Collantes, Carmen, Stone, Eric A., Wu, Philip, Field, Matthew A., Andrews, Thomas D., Cho, Eun, Pascual, Virginia, Cook, Matthew C., Vinuesa, Carola G.

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Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands von Linossi, Edmond M., Li, Kunlun, Veggiani, Gianluca, Tan, Cyrus, Dehkhoda, Farhad, Hockings, Colin, Calleja, Dale J., Keating, Narelle, Feltham, Rebecca, Brooks, Andrew J., Li, Shawn S., Sidhu, Sachdev S., Babon, Jeffrey J., Kershaw, Nadia J., Nicholson, Sandra E.

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Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK von Morris, Rhiannon, Zhang, Yaoyuan, Ellyard, Julia I., Vinuesa, Carola G., Murphy, James M., Laktyushin, Artem, Kershaw, Nadia J., Babon, Jeffrey J.

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The Role of LNK (SH2B3) in the Regulation of JAK-STAT Signalling in Haematopoiesis von Morris, Rhiannon, Butler, Liesl, Perkins, Andrew, Kershaw, Nadia J, Babon, Jeffrey J

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Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands von Linossi, Edmond M., Li, Kunlun, Veggiani, Gianluca, Tan, Cyrus, Dehkhoda, Farhad, Hockings, Colin, Calleja, Dale J., Keating, Narelle, Feltham, Rebecca, Brooks, Andrew J., Li, Shawn S., Sidhu, Sachdev S., Babon, Jeffrey J., Kershaw, Nadia J., Nicholson, Sandra E.

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Leukemia inhibitory factor (LIF) von Nicola, Nicos A, Babon, Jeffrey J

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