Molecular Recognition of Protein−Ligand Complexes:  Applications to Drug Design von Babine, Robert E, Bender, Steven L

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Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2 von Navaneetham, Duraiswamy, Jin, Lei, Pandey, Pramod, Strickler, James E., Babine, Robert E., Abdel-Meguid, Sherin S., Walsh, Peter N.

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Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions von Jin, Lei, Pandey, Pramod, Babine, Robert E., Gorga, Joan C., Seidl, Katherine J., Gelfand, Ellen, Weaver, David T., Abdel-Meguid, Sherin S., Strickler, James E.

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Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants von Lin, Jian, Deng, Hongfeng, Jin, Lei, Pandey, Pramod, Quinn, Jesse, Cantin, Susan, Rynkiewicz, Michael J, Gorga, Joan C, Bibbins, Frank, Celatka, Cassandra A, Nagafuji, Pamela, Bannister, Thomas D, Meyers, Harold V, Babine, Robert E, Hayward, Neil J, Weaver, David, Benjamin, Howard, Stassen, Frans, Abdel-Meguid, Sherin S, Strickler, James E

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Structurally similar estradiol analogs uniquely alter the regulation of intracellular signaling pathways von Yarger, James G, Babine, Robert E, Bittner, Michael, Shanle, Erin, Xu, Wei, Hershberger, Pamela, Nye, Steven H

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Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine von Deng, Hongfeng, Bannister, Thomas D., Jin, Lei, Babine, Robert E., Quinn, Jesse, Nagafuji, Pamela, Celatka, Cassandra A., Lin, Jian, Lazarova, Tsvetelina I., Rynkiewicz, Michael J., Bibbins, Frank, Pandey, Pramod, Gorga, Joan, Meyers, Harold V., Abdel-Meguid, Sherin S., Strickler, James E.

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The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors von Jin, Lei, Pluskey, Scott, Petrella, Eugene C, Cantin, Susan M, Gorga, Joan C, Rynkiewicz, Michael J, Pandey, Pramod, Strickler, James E, Babine, Robert E, Weaver, David T, Seidl, Katherine J

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FKBP immunophilin patents for neurological disorders von Babine, Robert E, Villafranca, J Ernest, Gold, Bruce G

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Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor X... von Pandey, Pramod, Babine, Robert E., Weaver, David T., Jin, Lei, Abdel-Meguid, Sherin S., Strickler, James E.

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Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis von Wang, Minmin, Winneroski, Leonard L., Ardecky, Robert J., Babine, Robert E., Brooks, Dawn A., Etgen, Garret J., Hutchison, Darrell R., Kauffman, Raymond F., Kunkel, Aaron, Mais, Dale E., Montrose-Rafizadeh, Chahrzad, Ogilvie, Kathleen M., Oldham, Brian A., Peters, Mary K., Rito, Christopher J., Rungta, Deepa K., Tripp, Allie E., Wilson, Sarah B., Xu, Yanping, Zink, Richard W., McCarthy, James R.

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The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine von Jin, Lei, Pluskey, Scott, Petrella, Eugene C., Cantin, Susan M., Gorga, Joan C., Rynkiewicz, Michael J., Pandey, Pramod, Strickler, James E., Babine, Robert E., Weaver, David T., Seidl, Katherine J.

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Abstract 1721: A steroid-based drug that binds estrogen receptor beta can inhibit cancer cell proliferation by blocking chromosome replication von Weitman, Steven D., Bittner, Michael, Hershberger, Pamela, Babine, Robert E., Nye, Steven, Yarger, James

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Revision of assignment of structure to the pyrrolodiazepinone antitumor antibiotic sibiromycin von Parker, Kathlyn A, Babine, Robert E

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies von Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Lee, Caroline A, Reich, Siegfried H, Prins, Thomas J, Marakovits, Joseph T, Littlefield, Ethel S, Zhou, Ru, Tikhe, Jayashree, Ford, Clifford E, Wallace, Michael B, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, Harr, James E. V, DeLisle, Dorothy M, Worland, Stephen T

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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies von Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Reich, Siegfried H, Marakovits, Joseph T, Prins, Thomas J, Zhou, Ru, Tikhe, Jayashree, Littlefield, Ethel S, Bleckman, Ted M, Wallace, Michael B, Little, Thomas L, Ford, Clifford E, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, DeLisle, Dorothy M, Worland, Stephen T

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Molecular Recognition of Proteinminus signLigand Complexes: Applications to Drug Design von Babine, Robert E., Bender, Steven L.

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Synthesis and biological evaluation of a series of HIV-1 protease inhibitors von Trova, Michael P., Babine, Robert E., Byrn, Randal A., Casscles, Wellington T., Hastings, Richard C., Hsu, Grace C., Jirousek, Michael R., Johnson, Bernard D., Kerwar, Suresh S., Schow, Steven R., Wissner, Allan, Zhang, Nan, Wick, Michael M.

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compostos, composições farmacêuticas, kit ou artigo farmacêutico embalado, e método de tratamento de um distúrbio mediado por carm1 von GIDEON SHAPIRO, ROBERT E. BABINE, RICHARD CHESWORTH, LEI JIN, Oscar Miguel Moradei

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CARM1 INHIBITORS AND USES THEREOF von Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei

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Carm1 inhibitors and uses thereof von Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei

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