Targeting of MIR-518D Reduces Chemoresistance in Hepatocellular Carcinoma Cell Lines von Ramos, D.F, Tussy, P.F, Perugorria, M.J, Bañales, J.M, Briz, Ó, Herráez, E, Marín, J.J.G, Mato, J.M, Chantar, M.L.M

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P1182 : MIR-506 is upregulated by pro-inflammatory cytokines in human cholangiocytes and inhibits cell proliferation and adhesion von Erice, O, Muñoz Garrido, P, Vaquero, J, Perugorria, M.J, Fernandez Barrena, M.G, Sáez, E, Merino, M, Arbelaiz, A, Santos Laso, Á, Jimenez Agüero, R, Marzioni, M, LaRusso, N.F, Garcia Marin, J.J, Bujanda, L, Bañales, J.M

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691 CHARACTERIZATION OF THE PURINOME ON THE BILIARY EPITHELIA von Godoy, V, Bañales, J.M, Medina, J.F, Pastor-Anglada, M

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P1183 : Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease von Muñoz, P, Garcia Marín, J.J, Perugorria, M.J, Urribarri, A.D, Saez, E, Uriz, M, Sarvide, S, Portu, A, Concepción, A, Rodriguez Romero, M, Monte, M.J, Santos-Laso, A, Hijona, E, Jimenez-Agüero, R, Marzioni, M, Beuers, U, Masyuk, T.V, LaRusso, N.F, Prieto, J, Drenth, J.P.H, Bujanda, L, Bañales, J.M

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Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression von Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J.J., O'Rourke, C.J., Andersen, J.B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L., Trauner, M., Bujanda, L., Perugorria, M.J., Banales, J.M.

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115P Inhibition of KLF5 reduces tumor growth and sensitizes to chemotherapy-induced cell death in experimental models of cholangiocarcinoma von Landa Magdalena, A., Rodrigues, P.M., Erice, O., Paiva, N.A., Fernandez-Barrena, M.G., Olaizola, P., Lapitz, A., O'Rourke, C.J., Andersen, J.B., Calvisi, D.F., Azkargorta, M., Elortza, F., Goicoechea, I., Lawrie, C.H., Bujanda, L., Perugorria, M.J., Bañales, J.M.

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New evidence supporting the biliary bicarbonate umbrella theory von Fernandez-Barrena, M.G, Barcena-Varela, M, Banales, J.M

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P1079 : PNPLA3 variant p.I148M improves response to bariatric surgery in obese patients with fatty liver disease von Krawczyk, M, Jiménez-Agüero, R, Aluztiza, J.M, Emparanza, J.I, Lammert, F, Banales, J.M

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FRI-044 - Targeting of MIR-518D Reduces Chemoresistance in Hepatocellular Carcinoma Cell Lines von Ramos, D.F., Tussy, P.F., Perugorria, M.J., Bañales, J.M., Briz, Ó., Herráez, E., Marín, J.J.G., Mato, J.M., Chantar, M.L.M.

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The Common Prosteatotic PNPLA3 (Adiponutrin) p.I148M Variant Might Protect against Gallstone Disease von Krawczyk, M, Jiménez-Agüero, R, Perugorria, M.J, Gallego, L, Bujanda, L, Lammert, F, Banales, J.M

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Genetic and epigenetic bases of the relationship between reduced OCT1 expression and poor response to sorafenib in hepatocellular carcinoma and cholangiocarcinoma von Al-Abdulla, R, Lozano, E, Macias, R.I, O’Rourke, C.J, Perez, M.J, Serrano, M.A, Romero, M.R, Monte, M.J, Herraez, E, Briz, O, Banales, J.M, Bujanda, L, Geier, A, Andersen, J.B, Marin, J.J

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Development of novel epigenetic inhibitors for the treatment of hepatocellular carcinoma von Bárcena-Varela, M, Oyarzabal, J, Banales, J.M, Prieto, J, Alvarez-Asiain, L, Prosper, F, Berasain, C, Avila, M.A, Fernandez-Barrena, M.G

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The anti-inflammatory receptor TREM-2 protects the liver from hepatocellular carcinoma development von Esparza-Baquer, A, Labiano, I, Erice, O, Sharif, O, Oakley, F, Lapitz, A, Olaizola, P, Lee-Law, P.Y, Hijona, E, Jiménez-Agüero, R, Knapp, S, Mann, D.A, Bujanda, L, Banales, J.M, Perugorria, M.J

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Comprehensive NAFLD diagnosis based on a noninvasive metabolomic approach in a liquid biopsy von Puri, P, Martinez-Arranz, I, Mincholé, I, Idowu, M.O, Mayo, R, Dufour, J.-F, Romero-Gómez, M, Bruha, R, Crespo, J, Banales, J.M, García-Monzón, C, Martín-Duce, A, Alonso, C, Ortiz, P, Noureddin, M, Lu, S.C, Bedossa, P, Sanyal, A.J, Mato, J.M

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P1317 : Efficacy of ursodeoxycholic acid as a volume reducing treatment for symptomatic polycystic liver disease: An international, multicenter, randomized controlled trial von D’Agnolo, H.M, Gevers, T.J, Riaño, I, Bujanda, L, Takkenberg, B, Beuers, U, Banales, J.M, Drenth, J.P

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Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma von Arbelaiz, A, Azkargorta, M, Santos-Laso, Á, Perugorria, M.J, Erice, O, Gonzalez, E, Lapitz, A, Izquierdo, L, Olaizola, P, Lee, P.Y, Arregi, A, Jimenez-Aguero, R, Lacasta, A, Ibarra, C, Sánchez-Campos, A, Jimeno, J.P, Krawczyk, M, Lammert, F, Marzioni, M, Macias, R, Marín, J.J, Patel, T, Gores, G, Martinez, I, Elortza, F, Falcón-Pérez, J.M, Bujanda, L, Banales, J.M

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Novel Serum Lipidomic Signature Correlates with the Grade of Steatosis Measured Biochemically and by Magnetic Resonance Imaging von Jimenez-Agüero, R, Bujanda, L, Arretxe, E, Balgoma, D, Perugorria, M.J, Alonso, C, Eizaguirre, E, Krawczyk, M, Lammert, F, Castro, A, Banales, J.M

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TREM-2 Protects the Liver from Immune-Mediated Hepatocellular Damage von Perugorria, M.J, Sharif, O, Oakley, F, Esparza-Baquer, A, Korosec, A, Mann, J, Labiano, I, Tiniakos, D, Gawish, R, Jiménez-Agüero, R, Bujanda, L, Banales, J.M, Knapp, S, Mann, D.A

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MIR-873 Promotes Liver De-Differentiation and Fibrosis Targeting Glycine-N-Methyl Transferase von Fernandez-Tussy, P, Fernández-Ramos, D, Lopitz-Otsoa, F, Barbier-Torres, L, Zubiete-Franco, I, de Juan, V.G, Bruix, J, Villa, E, Fraga, M, Fernández, A.F, Fabregat, I, Perugorria, M.J, Banales, J.M, Delgado, T.C, Varela-Rey, M, Beraza, N, Lu, S.C, Mato, J.M, Martínez-Chantar, M.L

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Nlrp3 inflammasome activation by microbial products leads to Il-18 synthesis and impaired epithelial barrier function in cholangiocytes von Maroni, L, Agostinelli, L, Saccomanno, S, Mingarelli, E, Rychlicki, C, De Minicis, S, Banales, J.M, Benedetti, A, Baroni, G. Svegliati, Marzioni, M

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