Novel CFTR Chloride Channel Activators Identified by Screening of Combinatorial Libraries Based on Flavone and Benzoquinolizinium Lead Compounds von Galietta, L J, Springsteel, M F, Eda, M, Niedzinski, E J, By, K, Haddadin, M J, Kurth, M J, Nantz, M H, Verkman, A S

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Dioxazocinium Ortho Esters: A Class of Highly pH-Vulnerable Amphiphiles von By, Kolbot, Nantz, Michael H.

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Preclinical Mechanisms of Topical PRN473, a Bruton Tyrosine Kinase Inhibitor, in Immune-Mediated Skin Disease Models von Xing, Yan, Chu, Katherine A, Wadhwa, Jyoti, Chen, Wei, Zhu, Jiang, Bradshaw, J Michael, Shu, Jin, Foulke, Matthew C, Loewenstein, Natalie, Nunn, Philip, By, Kolbot, Phiasivongsa, Pasit, Goldstein, David M, Langrish, Claire L

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Dioxazocinium Ortho Esters: A Class of Highly pH-Vulnerable Amphiphiles von By, Kolbot, Nantz, Michael H.

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Crystalline Forms 2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy-Phenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1- YL]Piperidine-1-Carbonyl]-4-Methyl-4-[4-(Oxetan-3-YL)Piperazin-1-YL]Pent-2- Enenitrile von By, Kolbot, Phiasivongsa, Pasit, Baum, Jean

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Crystalline forms of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)-1H-pyrazolo[3,4-D]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile von By, Kolbot, Phiasivongsa, Pasit, Baum, Jean

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Crystalline Forms of 2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy-Phenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1-YL]Piperidine-1-Carbonyl]-4,4-Dimethylpent-2-Enenitrile von By, Kolbot, Zhu, Jiang, Masjedizadeh, Mohammad R, Phiasivongsa, Pasit

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Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain von Springsteel, Mark F, Galietta, Luis J.V, Ma, Tonghui, By, Kolbot, Berger, Gideon O, Yang, Hong, Dicus, Christopher W, Choung, Wonken, Quan, Chao, Shelat, Anang A, Guy, R.Kiplin, Verkman, A.S, Kurth, Mark J, Nantz, Michael H

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Synthesis of 3,3-bis(3-fluorophenyl)-[2,3-3H2]-1-propanamine hydrochloride ([3H2]-NPS 846·HCl): a novel ligand for the NMDA receptor von Moe, Scott T., Smith, Daryl L., By, Kolbot, Egan, Judith A., Filer, Crist N.

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Crystalline forms of 2-[3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4,4-dimethylpent-2-enenitrile von Masjedizadeh, Mohammad Reza, By, Kolbot, Zhu, Jiang, Phiasivongsa, Pasit

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CRYSTALLINE FORMS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4-[4-(OXETAN-3-YL)PIPERAZIN-1-YL]PENT-2-ENENITRILE von By, Kolbot, Phiasivongsa, Pasit, Baum, Jean

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Solid Forms of 2-[3-[4-Amino-3-(2-Fluoro-4-Phenoxy-Phenyl)Pyrazolo[3,4-d]Pyrimidin-1-YL] Piperidine-1-Carbonyl]-4-Methyl-4-[4-(Oxetan-3-YL)Piperazin-1-YL]Pent-2-Enenitrile von Chu, Katherine, By, Kolbot, Zhu, Jiang, Masjedizadeh, Mohammad R, Phiasivongsa, Pasit

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Solid forms of 2-[3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile von Masjedizadeh, Mohammad Reza, Chu, Katherine, By, Kolbot, Zhu, Jiang, Phiasivongsa, Pasit

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CRYSTALLINE FORMS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4,4-DIMETHYLPENT-2-ENENITRILE von Masjedizadeh, Mohammad Reza, By, Kolbot, Zhu, Jiang, Phiasivongsa, Pasit

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Processes for making triazolo[4,5D] pyramidine derivatives and intermediates thereof von Jones, William Benton, By, Kolbot, Wolfe, Bradley Hamilton

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SOLID FORMS OF 2-[3-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4-[4-(OXETAN-3-YL)PIPERAZIN-1-YL]PENT-2-ENENITRILE von Masjedizadeh, Mohammad Reza, Chu, Katherine, By, Kolbot, Zhu, Jiang, Phiasivongsa, Pasit

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Fremgangsmåter for å fremstille stereoisomere forbindelser som er nyttige i behandlingen av sykdommer i mage-, tarm- og sentralnervesystemet von Pang, Ponny, By, Kolbot, Yeh, J B

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PROCESSES FOR MAKING TRIAZOLO[4,5D] PYRAMIDINE DERIVATIVES AND INTERMEDIATES THEREOF von Jones, William Benton, By, Kolbot, Wolfe, Bradley Hamilton

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Prodrugs of peptide epoxy ketone protease inhibitors von Peng, Ge, Luehr, Gary W, By, Kolbot, Anik, Shabbir T, Phiasivongsa, Pasit

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Synthesis of a C(4)–C(9) eleutheside template from d -glucal von By, Kolbot, Kelly, Patrick A, Kurth, Mark J, Olmstead, Marilyn M, Nantz, Michael H

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