Living systematic review: 1. Introduction—the why, what, when, and how von Synnot, Anneliese, Turner, Tari, Simmonds, Mark, Akl, Elie A., McDonald, Steve, Salanti, Georgia, Meerpohl, Joerg, MacLehose, Harriet, Hilton, John, Tovey, David, Shemilt, Ian, Hilton, John, Akl, Elie, Pestridge, Charlotte, Horsley, Tanya, Armstrong, Rebecca, Plovnick, Robert, Arno, Anneliese, Au, Agnes, Johnston, Renea, Rada, Gabriel, Bagg, Matthew, Jones, Arwel, Ravaud, Philippe, Boden, Catherine, Kahale, Lara, Richter, Bernt, Boisvert, Isabelle, Keshavarz, Homa, Ryan, Rebecca, Brandt, Linn, Kolakowsky-Hayner, Stephanie A., Salama, Dina, Brazinova, Alexandra, Nagraj, Sumanth Kumbargere, Salanti, Georgia, Buchbinder, Rachelle, Lasserson, Toby, Santaguida, Lina, Champion, Chris, Lawrence, Rebecca, Schünemann, Holger J., Charidimou, Andreas, Leucht, Stefan, Shemilt, Ian, Low, Nicola, Sherifali, Diana, Churchill, Rachel, MacLehose, Harriet, Simmonds, Mark, Cossi, Marie-Joelle, Counotte, Michel, Marshall, Iain, Soares-Weiser, Karla, Craigie, Samantha, Marshall, Rachel, Srikanth, Velandai, Martin, Nicole, Martínez García, Laura, Danko, Kristen, Taylor, Mark, Donoghue, Emma, Maxwell, Lara J., Thayer, Kris, Dressler, Corinna, McAuley, James, Thomas, James, Tritton, Roger, Elliott, Julian, McKenzie, Joanne, Tsafnat, Guy, Meerpohl, Joerg, Tugwell, Peter, Merner, Bronwen, Featherstone, Robin, Mondello, Stefania, Foxlee, Ruth, Morley, Richard, van Valkenhoef, Gert, Munafo, Marcus, Gerrity, Martha, Munn, Zachary, Wallace, Byron, Glasziou, Paul, Murano, Melissa, Wallace, Sheila A., Newman, Kristine, Watts, Chris, Nieuwlaat, Robby, Gurusamy, Kurinchi, Nikolakopoulou, Adriani, Weigl, Aaron, Hartling, Lisa, Wiercioch, Wojtek, Wolfenden, Luke, Pahwa, Manisha, Yepes Nuñez, Juan José, Yost, Jennifer, Hill, Sophie, Pearson, Leslea

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Living systematic reviews: 2. Combining human and machine effort von Marshall, Iain, McDonald, Steven, Mavergames, Chris, Shemilt, Ian, Turner, Tari, Elliott, Julian, Agoritsas, Thomas, Hodder, Rebecca, Pestridge, Charlotte, Albrecht, Lauren, Horsley, Tanya, Platt, Joanne, Nguyen, Phi Hung, Plovnick, Robert, Arno, Anneliese, Ivers, Noah, Quinn, Gail, Au, Agnes, Rada, Gabriel, Bagg, Matthew, Jones, Arwel, Ravaud, Philippe, Boden, Catherine, Kahale, Lara, Boisvert, Isabelle, Keshavarz, Homa, Ryan, Rebecca, Kolakowsky-Hayner, Stephanie A., Salama, Dina, Brazinova, Alexandra, Nagraj, Sumanth Kumbargere, Salanti, Georgia, Santaguida, Lina, Lawrence, Rebecca, Chandler, Jackie, Les, Zbigniew, Schünemann, Holger J., Charidimou, Andreas, Leucht, Stefan, Shemilt, Ian, Chou, Roger, Low, Nicola, Sherifali, Diana, Churchill, Rachel, Maas, Andrew, Siemieniuk, Reed, MacLehose, Harriet, Simmonds, Mark, Skoetz, Nicole, Marshall, Iain, Soares-Weiser, Karla, Craigie, Samantha, Marshall, Rachel, Srikanth, Velandai, Dahm, Philipp, Sullivan, Katrina, Danilkewich, Alanna, Martínez García, Laura, Synnot, Anneliese, Danko, Kristen, Mavergames, Chris, Taylor, Mark, Maxwell, Lara J., Thayer, Kris, Dressler, Corinna, McAuley, James, Egan, Cathy, Elliott, Julian, Tsafnat, Guy, Elliott, Sarah A., Etxeandia, Itziar, Merner, Bronwen, Turgeon, Alexis, Mondello, Stefania, Foxlee, Ruth, Morley, Richard, van Valkenhoef, Gert, Garner, Paul, Munafo, Marcus, Vandvik, Per, Gerrity, Martha, Wallace, Byron, Murano, Melissa, Wallace, Sheila A., Watts, Chris, Grimshaw, Jeremy, Weeks, Laura, Gurusamy, Kurinchi, Nikolakopoulou, Adriani, Weigl, Aaron, Haddaway, Neal, Wells, George, Hayden, Jill, Page, Matthew, Wolfenden, Luke, Helfand, Mark, Yepes Nuñez, Juan José, Higgins, Julian, Pardo, Jordi Pardo, Yost, Jennifer

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Living systematic reviews: 4. Living guideline recommendations von Akl, Elie A., Meerpohl, Joerg J., Elliott, Julian, Kahale, Lara A., Hilton, John, Perron, Caroline, Akl, Elie, Hodder, Rebecca, Pestridge, Charlotte, Albrecht, Lauren, Horsley, Tanya, Platt, Joanne, Nguyen, Phi Hung, Plovnick, Robert, Arno, Anneliese, Ivers, Noah, Au, Agnes, Jones, Arwel, Ravaud, Philippe, Boden, Catherine, Kahale, Lara, Richter, Bernt, Boisvert, Isabelle, Keshavarz, Homa, Brandt, Linn, Kolakowsky-Hayner, Stephanie A., Salama, Dina, Brazinova, Alexandra, Nagraj, Sumanth Kumbargere, Salanti, Georgia, Lasserson, Toby, Santaguida, Lina, Champion, Chris, Chandler, Jackie, Les, Zbigniew, Schünemann, Holger J., Charidimou, Andreas, Leucht, Stefan, Shemilt, Ian, Low, Nicola, Churchill, Rachel, Maas, Andrew, Siemieniuk, Reed, MacLehose, Harriet, Simmonds, Mark, Cossi, Marie-Joelle, Skoetz, Nicole, Marshall, Iain, Soares-Weiser, Karla, Craigie, Samantha, Marshall, Rachel, Srikanth, Velandai, Dahm, Philipp, Martin, Nicole, Synnot, Anneliese, Danko, Kristen, Mavergames, Chris, Taylor, Mark, Donoghue, Emma, Maxwell, Lara J., Thayer, Kris, Dressler, Corinna, McAuley, James, Thomas, James, Egan, Cathy, Elliott, Julian, Meerpohl, Joerg, Tugwell, Peter, Etxeandia, Itziar, Featherstone, Robin, Mondello, Stefania, Turner, Tari, Foxlee, Ruth, van Valkenhoef, Gert, Garner, Paul, Munafo, Marcus, Vandvik, Per, Gerrity, Martha, Wallace, Byron, Murano, Melissa, Wallace, Sheila A., Newman, Kristine, Watts, Chris, Grimshaw, Jeremy, Weeks, Laura, Gurusamy, Kurinchi, Nikolakopoulou, Adriani, Weigl, Aaron, Noel-Storr, Anna, Wells, George, Hartling, Lisa, O'Connor, Annette, Wiercioch, Wojtek, Hayden, Jill, Page, Matthew, Wolfenden, Luke, Helfand, Mark, Pardo, Jordi Pardo, Yost, Jennifer, Hill, Sophie

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Living systematic reviews: 3. Statistical methods for updating meta-analyses von Simmonds, Mark, Salanti, Georgia, McKenzie, Joanne, Elliott, Julian, Agoritsas, Thomas, Perron, Caroline, Akl, Elie, Hodder, Rebecca, Pestridge, Charlotte, Albrecht, Lauren, Platt, Joanne, Armstrong, Rebecca, Nguyen, Phi Hung, Arno, Anneliese, Ivers, Noah, Quinn, Gail, Johnston, Renea, Rada, Gabriel, Bagg, Matthew, Ravaud, Philippe, Richter, Bernt, Ryan, Rebecca, Brandt, Linn, Kolakowsky-Hayner, Stephanie A., Brazinova, Alexandra, Nagraj, Sumanth Kumbargere, Salanti, Georgia, Buchbinder, Rachelle, Lasserson, Toby, Champion, Chris, Lawrence, Rebecca, Santesso, Nancy, Chandler, Jackie, Schünemann, Holger J., Shemilt, Ian, Chou, Roger, Low, Nicola, Sherifali, Diana, Cnossen, Maryse C., Simmonds, Mark, Cossi, Marie-Joelle, Macleod, Malcolm, Counotte, Michel, Marshall, Iain, Soares-Weiser, Karla, Craigie, Samantha, Marshall, Rachel, Srikanth, Velandai, Martin, Nicole, Sullivan, Katrina, Danilkewich, Alanna, Martínez García, Laura, Synnot, Anneliese, Danko, Kristen, Mavergames, Chris, Donoghue, Emma, Thayer, Kris, Dressler, Corinna, McAuley, James, Thomas, James, McDonald, Steve, Tritton, Roger, Elliott, Julian, McKenzie, Joanne, Tsafnat, Guy, Meerpohl, Joerg, Tugwell, Peter, Merner, Bronwen, Turgeon, Alexis, Featherstone, Robin, Mondello, Stefania, Turner, Tari, van Valkenhoef, Gert, Munafo, Marcus, Vandvik, Per, Munn, Zachary, Wallace, Byron, Glasziou, Paul, Murano, Melissa, Wallace, Sheila A., Green, Sally, Newman, Kristine, Watts, Chris, Grimshaw, Jeremy, Nieuwlaat, Robby, Gurusamy, Kurinchi, Nikolakopoulou, Adriani, Weigl, Aaron, Noel-Storr, Anna, Wells, George, Hartling, Lisa, O'Connor, Annette, Wiercioch, Wojtek, Helfand, Mark, Pahwa, Manisha, Yepes Nuñez, Juan José, Higgins, Julian, Pardo, Jordi Pardo, Hill, Sophie, Pearson, Leslea

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Introduction to the Special Issue

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Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis von Chalmers, James D, Haworth, Charles S, Metersky, Mark L, Loebinger, Michael R, Blasi, Francesco, Sibila, Oriol, O’Donnell, Anne E, Sullivan, Eugene J, Mange, Kevin C, Fernandez, Carlos, Zou, Jun, Daley, Charles L

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Affirmative Practice With Transgender and Gender Nonconforming Youth: Expanding the Model von Edwards-Leeper, Laura, Leibowitz, Scott, Sangganjanavanich, Varunee Faii

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Missteps in Psychotherapy With Transgender Clients: Promoting Gender Sensitivity in Counseling and Psychological Practice von Mizock, Lauren, Lundquist, Christine

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Variability of Neogene Continental Climates in Northwest Europe - a detailed Study based on Microfloras von UTESCHER, TORSTEN, ASHRAF, ABDUL RAHMAN, DREIST, ANDREAS, DYBKJAER, KAREN, MOSBRUGGER, VOLKER, PROSS, JÖRG, WILDE, VOLKER

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Remembering Hans-Peter Künzi (1955–2020) von Gilmour, Christopher, Otafudu, Olivier Olela, Russo, Francesco G., Schauerte, Anneliese

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Terrorism and the Foreigner: A Decade of Tension around the Rule of Law in Europe von Baldaccini, Anneliese, Guild, Elspeth

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Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial von FitzGerald, J Mark, Barker, Peter, Goldman, Mitchell, Tolcachier, Alberto, Otaola, María, Arce, German, Saez, Maria Salazan, Peters, Matthew, Gibson, Peter, Thien, Francis, Bardin, Philip, Hew, Mark, Pez, Andreia, Metev, Hristo, Ivanov, Yavor, Peneva, Marinka, Dorscheid, Delbert, Veverka, Josef, Zindr, Vladimir, Devouassoux, Gilles, Taille, Camille, Goupil, Francois, Keller, Claus, Kirschner, Joachim, Beck, Ekkehard, Dichmann, Rolf, Overlack, Axel, Hoffmann, Martin, Rabe, Klaus, Deckelmann, Regina, Welte, Tobias, Shimoda, Terufumi, Nagakura, Toshikazu, Takahashi, Hisaho, Haida, Michiko, Kimura, Goro, Shijyubo, Noriharu, Tanaka, Akihiko, Ohdaira, Tetsuro, Takahashi, Toshiki, Miki, Hiroshi, Diaz, Javier, Felix, Efrain, Daly, Alejandro, Estrella, Rolando, Springer, Ewa, Kwaśniewski, Artur, Rybicka-Liszewska, Elżbieta, Bodzenta-Łukaszyk, Anna, Mihaescu, Traian, Apti, Ghiulten, Trailescu, Ana, Sokurenko, Sergei, Ilyashevich, Inna, Stitsenko, Irina, Goncharova, Svetlana, Ezhov, Andrey, Izmozherova, Nadezhda, Molotkov, Artem, Pavlysh, Elena, Chistyakov, Valery, Bruning, Axel, Lee, Sang Haak, Lee, Sang Pyo, Yoo, Kwang Ha, Yoon, Hyoungkyu, Arias Guillen, Miguel, Sánchez-Toril López, Fernando, García-Cosio Piqueras, Borja, Valero Santiago, Antonio Luis, Bjermer, Leif, Gemicioglu, Bilun, Arinc, Sibel, Iashyna, Liudmyla, Mostovoy, Yuriy, Ostrovskyy, Mykola, Krakhmalova, Olena, Gavrysyuk, Volodymyr, Win, Thida, Babu, Suresh, Zwetchkenbaum, John, Bleecker, Eugene, Alpizar, Sady, Rodriguez, Hector, Pouzar, Joe, Davis, Enrique, Karimjee, Najmuddin, Shaikh, Zeeshan, Nish, William, Alvarez, German, Parikh, Purvi, Perez, Guido, Chupp, Geoffrey, Tarpay, Martha, Merchant, Rajan, Shapero, Paul, Moss, Mark, Boyd, Amy, Johnson II, Thomas, Ngo, Chau

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Digital Education in Health Professions: The Need for Overarching Evidence Synthesis von Car, Josip, Carlstedt-Duke, Jan, Tudor Car, Lorainne, Posadzki, Pawel, Whiting, Penny, Zary, Nabil, Atun, Rifat, Majeed, Azeem, Campbell, James

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Innovations in Research With Transgender and Gender Nonconforming People and Their Communities von dickey, lore m., Hendricks, Michael L., Bockting, Walter O.

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Palaeoclimate Evolution in Siberia and the Russian Far East from the Oligocene to Pliocene – Evidence from Fruit and Seed Floras von POPOVA, SVETLANA, UTESCHER, TORSTEN, GROMYKO, DMITRY, BRUCH, ANGELA, MOSBRUGGER, VOLKER

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Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study von Korn, Stephanie, Corren, Jonathan, Bednarczyk, Artur, Ponnarambil, Sandhia, Caveney, Scott, Almqvist, Gun, Simonsson, Linda, Lawson, Kaitlyn, Bowen, Karin, Colice, Gene, Hetzel, Jorge Lima, Antila, Martti Anton, Bezerra, Patricia Gomes de Matos, Lemiere, Catherine, Mitchell, Patrick, Chouinard, Guy, Cheema, Amarjit S, Yang, William Ho-Ching, Philteos, George, Bourdin, Arnaud, Taille, Camille, Leroyer, Christophe, Beurnier, Antoine, Garcia, Gilles, Girodet, Pierre-Olivier, Blanc, François-Xavier, Wanin, Stéphanie, Just, Jocelyne, Geßner, Christian, Buhl, Roland Otto, Kornmann, Marc Oliver, Linnhoff, Anneliese, Ludwig-Sengpiel, Andrea, Steffen, Heiner, Hoffmann, Martin, Kirschner, Joachim, Schmidt, Olaf, Wand, Ori, Izbicki, Gabriel, Berkman, Neville, Adir, Yochai, Rewerska, Barbara, Kurbacheva, Oksana, Mikhailov, Sergey L, Albanna, Amr, Bernhardi, David, Hoosen, Farzana, Naidoo, Visvakuren, Nell, Haylene, Padayachee, Trevenesan, Reddy, Jeevren, Petrick, Friedrich, Vawda, Zubar Fazal Ahmed, Park, Hae-Sim, Cho, You Sook, Lee, Byung Jae, Chang, Yoon-Seok, Lee, Sook Young, Yoon, HyoungKyu, Min, Kyung Hoon, Cho, Young Joo, Sheu, Chau-Chyun, Tu, Chih-Yen, Lee, Kang-Yun, Ediger, Dane, Kalkan, Ilkay Koca, Makieieva, Nataliia, Ostrovskyy, Mykola, Dytyatkovs'ka, Yevgeniya, Mostovoy, Yuriy Mykhaylovych, Lebed, Kyrylo, Mooring, Timothy, Thompson, Ernest, Chappel, Christopher M, Cole, Jeremy, Greenwald, Gary I, Jones, Conigliaro, Klein, Ryan Mitchell, Weinstein, Steven F, Windom, Hugh H, Kao, Neil L, Bhat, Saligrama, Aish, Bassil, Kerwin, Edward M, Delgado, John Palsted, Thompson, Charles A, Alpizar, Sady A, Vadgama, Sanjay Virgi, Zafar, Zahid, Lugogo, NJira, Jain, Neal, Sher, Lawrence D, Andrawis, Nabil S, Fuentes, David, Gonzalez, Erika G, Totszollosy Tarpay, Martha M, Tillinghast, Jeffrey P, Korenblat, Phillip E, Shenoy, Kartik, Que, Loretta

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Evaluation of the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma (SOURCE): a randomised, placebo-controlled, phase 3 study von Wechsler, Michael E, Menzies-Gow, Andrew, Brightling, Christopher E, Kuna, Piotr, Korn, Stephanie, Welte, Tobias, Griffiths, Janet M, Sałapa, Kinga, Hellqvist, Åsa, Almqvist, Gun, Lal, Harbans, Kaur, Primal, Skärby, Tor, Colice, Gene, Cambursano, Victor H, Fernandez, Marcelo J, Scherbovsky, Fernando D, Yanez, Anahi, Tolcachier, Alberto J, Stok, Ana M, Verra, Fernando J B, Korn, Stephanie, Forster, Karin, Rolke, Mathias, Ludwig-Sengpiel, Andrea, Schmoller, Tibor, Schmidt, Olaf, Milger-Kneidinger, Katrin, Hoffmann, Martin, Temme, Hilke, Linnhoff, Anneliese, Welte, Tobias, Kirschner, Joachim, Kuna, Piotr, Rewerska, Barbara, Pisarczyk-Bogacka, Ewa, Haak Lee, Sang, Jae Lee, Byung, Park, Heung-Woo, Park, Jung-Won, Young Lee, Sook, Sook Cho, You, Ho Lee, Kwan, Bavbek, Sevim, Gemicioglu, Bilun, Ediger, Dane, Koca Kalkan, Ilkay, Hanta, Ismail, Yorgancioglu, Arzu, DytyatkovsKa, Yevgeniya, Mostovoy, Yuriy M, Lebed, Kyrylo, Yakovenko, Oleh, Bernstein, David I, Tillinghast, Jeffrey P, Que, Loretta, Madison, Jan, Rambasek, Todd, Shenoy, Kartik, Thompson, Charles A, Chappel, Christopher M, Hudes, Golda, Sorial, Ehab, Kureishy, Shahrukh A, Rehman, Syed M, Lugogo, Njira, Gonzalez, Erika G, Umeh, Fred C, Boren, Eric J, Sigmon, Jason, Ismail, Hummayun, Mohan, Arjun, Bansal, Sandeep, Kaelin, Thomas D

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WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy von Kannan, Meghna, Bayam, Efil, Wagner, Christel, Rinaldi, Bruno, Kretz, Perrine F., Tilly, Peggy, Roos, Marna, McGillewie, Lara, Bär, Séverine, Minocha, Shilpi, Chevalier, Claire, Po, Chrystelle, Project, Sanger Mouse Genetics, Chelly, Jamel, Mandel, Jean-Louis, Borgatti, Renato, Piton, Amélie, Kinnear, Craig, Loos, Ben, Adams, David J., Hérault, Yann, Collins, Stephan C., Friant, Sylvie, Godin, Juliette D., Yalcin, Binnaz

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Palaeoclimatic Estimates for the Late Pliocene Based on Leaf Physiognomy from Western Yunnan, China von XIE, SANPING, BAINIAN, SUN, WU, JINYU, LIN, ZHICHENG, YAN, DEFEI, XIAO, LIANG

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Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project von Iorio, A., Skinner, M. W., Clearfield, E., Messner, D., Pierce, G. F., Witkop, M., Tunis, S., Akehurst, Ronald, Jain, Mohit, Pezalla, Edmund, Valentino, Leonard, Altemark, Andreas, Belinson, Suzanne, Booth, Jason, Dahm, Philipp, Dolan, Gerard, Facey, Karen, Gouw, Samantha, Hart, Daniel, Hilger, Anneliese, Hooper, Craig, Hoots, Keith, Jorgenson, James, Keene, Daniel, Kim, Joanne, Krassova, Snejana, LeCleir, Gregory, Lillicrap, David, Lopes, Maria, Marks, Peter, Monahan, Paul, Moscou‐Jackson, Gyasi, Murray, Jennifer, Mujoomdar, Michelle, Neufeld, Ellis, O'Hara, Jamie, O'Mahony, Brian, Österberg, Marie, Petrie, Charles, Pindolia, Vanita, Pipe, Steven, Pleil, Andreas, Reilly, Philip, Reiss, Ulrike, Rice, Michelle, Ruiz, Sol, Sandy, Lew, Sawyer, Eileen, Sharp, Michael, Sood, Amy, Spiegler, Clive, Tugwell, Peter, Weill, Alain, Werkö, Sophie, Wong, Wing Yen, Zelenkofske, Steven, Al Naber, Jennifer, King, Janelle, Simmons, Julie

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