Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches von Green, Jeffrey, Stapleton, Melanie R, Smith, Laura J, Artymiuk, Peter J, Kahramanoglou, Christina, Hunt, Debbie M, Buxton, Roger S

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Structure of a Wbl protein and implications for NO sensing by M. tuberculosis von Kudhair, Bassam K., Hounslow, Andrea M., Rolfe, Matthew D., Crack, Jason C., Hunt, Debbie M., Buxton, Roger S., Smith, Laura J., Le Brun, Nick E., Williamson, Michael P., Green, Jeffrey

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Mycobacterium tuberculosis WhiB1 is an essential DNA-binding protein with a nitric oxide-sensitive iron-sulfur cluster von Smith, Laura J, Stapleton, Melanie R, Fullstone, Gavin J M, Crack, Jason C, Thomson, Andrew J, Le Brun, Nick E, Hunt, Debbie M, Harvey, Evelyn, Adinolfi, Salvatore, Buxton, Roger S, Green, Jeffrey

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Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1 von Smith, Laura J, Stapleton, Melanie R, Buxton, Roger S, Green, Jeffrey

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EspD Is Critical for the Virulence-Mediating ESX-1 Secretion System in Mycobacterium tuberculosis von Chen, Jeffrey M, Boy-Röttger, Stefanie, Dhar, Neeraj, Sweeney, Nathan, Buxton, Roger S, Pojer, Florence, Rosenkrands, Ida, Cole, Stewart T

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Mechanistic Insight into the Nitrosylation of the [4Fe−4S] Cluster of WhiB-like Proteins von Crack, Jason C, Smith, Laura J, Stapleton, Melanie R, Peck, Jamie, Watmough, Nicholas J, Buttner, Mark J, Buxton, Roger S, Green, Jeffrey, Oganesyan, Vasily S, Thomson, Andrew J, Le Brun, Nick E

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Genomic mapping of cAMP receptor protein (CRP Mt) in Mycobacterium tuberculosis: relation to transcriptional start sites and the role of CRPMt as a transcription factor von Kahramanoglou, Christina, Cortes, Teresa, Matange, Nishad, Hunt, Debbie M, Visweswariah, Sandhya S, Young, Douglas B, Buxton, Roger S

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Global Analysis of the Regulon of the Transcriptional Repressor LexA, a Key Component of SOS Response in Mycobacterium tuberculosis von Smollett, Katherine L., Smith, Kimberley M., Kahramanoglou, Christina, Arnvig, Kristine B., Buxton, Roger S., Davis, Elaine O.

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Mycobacterium tuberculosis cAMP Receptor Protein (Rv3676) Differs from the Escherichia coli Paradigm in Its cAMP Binding and DNA Binding Properties and Transcription Activation Pro... von Stapleton, Melanie, Haq, Ihtshamul, Hunt, Debbie M., Arnvig, Kristine B., Artymiuk, Peter J., Buxton, Roger S., Green, Jeffrey

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Induced ectopic expression of HigB toxin in Mycobacterium tuberculosis results in growth inhibition, reduced abundance of a subset of mRNAs and cleavage of tmRNA von Schuessler, Dorothée L., Cortes, Teresa, Fivian‐Hughes, Amanda S., Lougheed, Kathryn E. A., Harvey, Evelyn, Buxton, Roger S., Davis, Elaine O., Young, Douglas B.

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Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence von Smith, Laura J, Bochkareva, Aleksandra, Rolfe, Matthew D, Hunt, Debbie M, Kahramanoglou, Christina, Braun, Yvonne, Rodgers, Angela, Blockley, Alix, Coade, Stephen, Lougheed, Kathryn E A, Hafneh, Nor Azian, Glenn, Sarah M, Crack, Jason C, Le Brun, Nick E, Saldanha, José W, Makarov, Vadim, Nobeli, Irene, Arnvig, Kristine, Mukamolova, Galina V, Buxton, Roger S, Green, Jeffrey

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Forkhead-associated (FHA) Domain Containing ABC Transporter Rv1747 Is Positively Regulated by Ser/Thr Phosphorylation in Mycobacterium tuberculosis von Spivey, Vicky L., Molle, Virginie, Whalan, Rachael H., Rodgers, Angela, Leiba, Jade, Stach, Lasse, Walker, K. Barry, Smerdon, Stephen J., Buxton, Roger S.

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A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene... von Rickman, Lisa, Scott, Colin, Hunt, Debbie M., Hutchinson, Thomas, Menéndez, M. Carmen, Whalan, Rachael, Hinds, Jason, Colston, M. Joseph, Green, Jeffrey, Buxton, Roger S.

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Long-Range Transcriptional Control of an Operon Necessary for Virulence-Critical ESX-1 Secretion in Mycobacterium tuberculosis von Hunt, Debbie M, Sweeney, Nathan P, Mori, Luisa, Whalan, Rachael H, Comas, Iñaki, Norman, Laura, Cortes, Teresa, Arnvig, Kristine B, Davis, Elaine O, Stapleton, Melanie R, Green, Jeffrey, Buxton, Roger S

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Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis von Chapman, Timothy M., Bouloc, Nathalie, Buxton, Roger S., Chugh, Jasveen, Lougheed, Kathryn E.A., Osborne, Simon A., Saxty, Barbara, Smerdon, Stephen J., Taylor, Debra L., Whalley, David

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Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2 von Stapleton, Melanie R, Smith, Laura J, Hunt, Debbie M, Buxton, Roger S, Green, Jeffrey

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New anti-tuberculosis agents amongst known drugs von Lougheed, Kathryn E.A, Taylor, Debra L, Osborne, Simon A, Bryans, Justin S, Buxton, Roger S

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Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response von Matange, Nishad, Hunt, Debbie M, Buxton, Roger S, Visweswariah, Sandhya S

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Effective inhibitors of the essential kinase PknB and their potential as anti-mycobacterial agents von Lougheed, Kathryn E.A, Osborne, Simon A, Saxty, Barbara, Whalley, David, Chapman, Tim, Bouloc, Nathalie, Chugh, Jasveen, Nott, Timothy J, Patel, Dony, Spivey, Vicky L, Kettleborough, Catherine A, Bryans, Justin S, Taylor, Debra L, Smerdon, Stephen J, Buxton, Roger S

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Structural and Functional Analysis of Phosphothreonine-Dependent FHA Domain Interactions von Pennell, Simon, Westcott, Sarah, Ortiz-Lombardía, Miguel, Patel, Dony, Li, Jiejin, Nott, Timothy J., Mohammed, Duaa, Buxton, Roger S., Yaffe, Michael B., Verma, Chandra, Smerdon, Stephen J.

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