Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury von Emal, Diba, Rampanelli, Elena, Stroo, Ingrid, Butter, Loes M, Teske, Gwendoline J, Claessen, Nike, Stokman, Geurt, Florquin, Sandrine, Leemans, Jaklien C, Dessing, Mark C

Volltext

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome von Iyer, Shankar S, Pulskens, Wilco P, Sadler, Jeffrey J, Butter, Loes M, Teske, Gwendoline J, Ulland, Tyler K, Eisenbarth, Stephanie C, Florquin, Sandrine, Flavell, Richard A, Leemans, Jaklien C, Sutterwala, Fayyaz S

Volltext

Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation von Bakker, Pieter J., Butter, Loes M., Kors, Lotte, Teske, Gwendoline J.D., Aten, Jan, Sutterwala, Fayyaz S., Florquin, Sandrine, Leemans, Jaklien C.

Volltext

Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury von Pulskens, Wilco P, Teske, Gwendoline J, Butter, Loes M, Roelofs, Joris J, van der Poll, Tom, Florquin, Sandrine, Leemans, Jaklien C

Volltext

The dysregulation of metabolic pathways and induction of the pentose phosphate pathway in renal ischaemia–reperfusion injury von Scantlebery, Angelique ML, Tammaro, Alessandra, Mills, James D, Rampanelli, Elena, Kors, Lotte, Teske, Gwendoline J, Butter, Loes M, Liebisch, Gerhard, Schmitz, Gerd, Florquin, Sandrine, Leemans, Jaklien C, Roelofs, Joris JTH

Volltext

Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction von Pulskens, Wilco P, Butter, Loes M, Teske, Gwendoline J, Claessen, Nike, Dessing, Mark C, Flavell, Richard A, Sutterwala, Fayyaz S, Florquin, Sandrine, Leemans, Jaklien C

Volltext

A Tissue-Specific Role for Nlrp3 in Tubular Epithelial Repair after Renal Ischemia/Reperfusion von Bakker, Pieter J, Butter, Loes M, Claessen, Nike, Teske, Gwendoline J.D, Sutterwala, Fayyaz S, Florquin, Sandrine, Leemans, Jaklien C

Volltext

TLR4 Promotes Fibrosis but Attenuates Tubular Damage in Progressive Renal Injury von PULSKENS, Wilco P, RAMPANELLI, Elena, TESKE, Gwendoline J, BUTTER, Loes M, CLAESSEN, Nike, LUIRINK, Ilse K, VAN DER POLL, Tom, FLORQUIN, Sandrine, LEEMANS, Jaklien C

Volltext

Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain von Uil, Melissa, Scantlebery, Angelique M. L., Butter, Loes M., Larsen, Per W. B., de Boer, Onno J., Leemans, Jaklien C., Florquin, Sandrine, Roelofs, Joris J. T. H.

Volltext

The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury von Leemans, Jaklien C, Butter, Loes M, Pulskens, Wilco P C, Teske, Gwendoline J D, Claessen, Nike, van der Poll, Tom, Florquin, Sandrine

Volltext

Deficiency for the chemokine monocyte chemoattractant protein-1 aggravates tubular damage after renal ischemia/reperfusion injury von Stroo, Ingrid, Claessen, Nike, Teske, Gwendoline J D, Butter, Loes M, Florquin, Sandrine, Leemans, Jaklien C

Volltext

The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion von Dessing, Mark C., Tammaro, Alessandra, Pulskens, Wilco P., Teske, Gwendoline J., Butter, Loes M., Claessen, Nike, van Eijk, Marco, van der Poll, Tom, Vogl, Thomas, Roth, Johannes, Florquin, Sandrine, Leemans, Jaklien C.

Volltext

Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling von Zuurbier, Coert J, Jong, Willeke M C, Eerbeek, Otto, Koeman, Anneke, Pulskens, Wilco P, Butter, Loes M, Leemans, Jaklien C, Hollmann, Markus W

Volltext

Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney von Rampanelli, Elena, Ochodnicky, Peter, Vissers, Johannes PC, Butter, Loes M, Claessen, Nike, Calcagni, Alessia, Kors, Lotte, Gethings, Lee A, Bakker, Stephan JL, de Borst, Martin H, Navis, Gerjan J, Liebisch, Gerhard, Speijer, Dave, van den Bergh Weerman, Marius A, Jung, Bettina, Aten, Jan, Steenbergen, Eric, Schmitz, Gerd, Ballabio, Andrea, Florquin, Sandrine, Aerts, Johannes MFG, Leemans, Jaklien C

Volltext

Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation von Rampanelli, Elena, Orsó, Evelyn, Ochodnicky, Peter, Liebisch, Gerhard, Bakker, Pieter J., Claessen, Nike, Butter, Loes M., van den Bergh Weerman, Marius A., Florquin, Sandrine, Schmitz, Gerd, Leemans, Jaklien C.

Volltext

Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy von Tammaro, Alessandra, Stroo, Ingrid, Rampanelli, Elena, Blank, Froilan, Butter, Loes M, Claessen, Nike, Takai, Toshiyuki, Colonna, Marco, Leemans, Jaklien C, Florquin, Sandrine, Dessing, Mark C

Volltext

NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin von Scantlebery, Angelique M L, Uil, Melissa, Butter, Loes M, Poelman, Renée, Claessen, Nike, Girardin, Stephen E, Florquin, Sandrine, Roelofs, Joris J T H, Leemans, Jaklien C

Volltext

TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells von Tammaro, Alessandra, Scantlebery, Angelique M L, Rampanelli, Elena, Borrelli, Cristiana, Claessen, Nike, Butter, Loes M, Soriani, Alessandra, Colonna, Marco, Leemans, Jaklien C, Dessing, Mark C, Florquin, Sandrine

Volltext

Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase von Stroo, Ingrid, Stokman, Geurt, Teske, Gwen J. D., Raven, Anje, Butter, Loes M., Florquin, Sandrine, Leemans, Jaklien C.

Volltext

NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy von Liu, Ye, Kors, Lotte, Butter, Loes M, Stokman, Geurt, Claessen, Nike, Zuurbier, Coert J, Girardin, Stephen E, Leemans, Jaklien C, Florquin, Sandrine, Tammaro, Alessandra

Volltext