DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer von Worthley, D L, Whitehall, V L J, Buttenshaw, R L, Irahara, N, Greco, S A, Ramsnes, I, Mallitt, K -A, Le Leu, R K, Winter, J, Hu, Y, Ogino, S, Young, G P, Leggett, B A

Volltext

Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype von Whitehall, V L J, Dumenil, T D, McKeone, D M, Bond, C E, Bettington, M L, Buttenshaw, R L, Bowdler, L, Montgomery, G W, Wockner, L F, Leggett, B A

Volltext

Characterization of tumour-infiltrating lymphocytes and apoptosis in colitis-associated neoplasia: comparison with sporadic colorectal cancer von Michael-Robinson, JM, Pandeya, N, Walsh, MD, Biemer-Huttmann, A-E, Eri, RD, Buttenshaw, RL, Lincoln, D, Clouston, AD, Jass, JR, Radford-Smith, GL

Volltext

A case of myoepithelial carcinoma displaying biallelic inactivation of the tumour suppressor gene APC in a patient with familial adenomatous polyposis von Young, J, Barker, M, Robertson, T, Nasioulas, S, Tannenberg, A, Buttenshaw, R L, Knight, N, Jass, J R, Leggett, B A

Volltext

Severe upper gastrointestinal polyposis associated with sparse colonic polyposis in a familial adenomatous polyposis family with an APC mutation at codon 1520 von Leggett, B A, Young, J P, Biden, K, Buttenshaw, R L, Knight, N, Cowen, A E

Volltext

No evidence of increased risk of colorectal cancer in individuals heterozygous for the Cys282Tyr haemochromatosis mutation von Macdonald, Graeme A, Tarish, Jabsar, Whitehall, Vicki Jl, M, Sally J, Mellick, George D, Buttenshaw, Ron L, Johnson, Anthony G, Young, Joanne, Leggett, Barbara A

Volltext

Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability von Wynter, Coral V. A., Simms, Lisa A., Buttenshaw, Ron L., Biden, Kelli G., Young, Joanne, Leggett, Barbara A., Conrad, Rod J., Schoch, Estelle M., Jass, Jeremy R., Praga Pillay, S.

Volltext

Characteristics of metachronous colorectal carcinoma occurring despite colonoscopic surveillance von LEGGETT, B. A, CORNWELL, M, THOMAS, L. R, BUTTENSHAW, R. L, SEARLE, J, YOUNG, J, WARD, M

Volltext

BREAST MILK β-GLUCURONIDASE AND NEONATAL JAUNDICE von Gaffney, PhilipT, Buttenshaw, RonaldL, Ward, Michael, Diplock, RossD

Volltext

Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype von Whitehall, VLJ, Dumenil, TD, McKeone, DM, Bond, CE, Bettington, ML, Buttenshaw, RL, Bowdler, L, Montgomery, GW, Wockner, LF, Leggett, BA

Volltext

Oncogenic PIK3CA mutations in colorectal cancers and polyps von Whitehall, Vicki L.J., Rickman, Celestine, Bond, Catherine E., Ramsnes, Ingunn, Greco, Sonia A., Umapathy, Aarti, McKeone, Diane, Faleiro, Rebecca J., Buttenshaw, Ron L., Worthley, Daniel L., Nayler, Sam, Zhao, Zhen Zhen, Montgomery, Grant W., Mallitt, Kylie-Ann, Jass, Jeremy R., Matsubara, Nagahide, Notohara, Kenji, Ishii, Tatsuhiro, Leggett, Barbara A.

Volltext

Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development von Loh, Kim, Chia, June A., Greco, Sonia, Cozzi, Sarah-Jane, Buttenshaw, Ron L., Bond, Catherine E., Simms, Lisa A., Pike, Tanya, Young, Joanne P., Jass, Jeremy R., Spring, Kevin J., Leggett, Barbara A., Whitehall, Vicki L. J.

Volltext

Features of Colorectal Cancers with High-Level Microsatellite Instability Occurring in Familial and Sporadic Settings : Parallel Pathways of Tumorigenesis von Young, Joanne, Simms, Lisa A, Biden, Kelli G, Wynter, Coral, Whitehall, Vicki, Karamatic, Rozemary, George, Jill, Goldblatt, Jack, Walpole, Ian, Robin, Sally-Anne, Borten, Michael M, Stitz, Russell, Searle, Jeffrey, McKeone, Diane, Fraser, Leigh, Purdie, David R, Podger, Kay, Price, Rachael, Buttenshaw, Ron, Walsh, Michael D, Barker, Melissa, Leggett, Barbara A, Jass, Jeremy R

Volltext

Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer von Young, Joanne, Barker, Melissa A., Simms, Lisa A., Walsh, Michael D., Biden, Kelli G., Buchanan, Daniel, Buttenshaw, Ron, Whitehall, Vicki L.J., Arnold, Sven, Jackson, Leigh, Kambara, Takeshi, Spring, Kevin J., Jenkins, Mark A., Walker, Graeme J., Hopper, John L., Leggett, Barbara A., Jass, Jeremy R.

Volltext

Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers von SIMMS, L. A, RADFORD-SMITH, G, BIDEN, K. G, BUTTENSHAW, R, CUMMINGS, M, JASS, J. R, YOUNG, J, MELTZER, S. J, LEGGETT, B. A

Volltext

T2076 DNA Methylation Profiles Within Normal Human Colorectal Mucosa Are Gene Specific and Influenced By Region, Patient Age and Pathology von Worthley, Daniel L, Whitehall, Vicki, Buttenshaw, Ron, Scott, Justin R, Leggett, Barbara A

Volltext

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability von BIDEN, K. G, SIMMS, L. A, YOUNG, J, CUMMINGS, M, BUTTENSHAW, R, SCHOCH, E, SEARLE, J, GOBE, G, JASS, J. R, MELTZER, S. J, LEGGETT, B. A

Volltext

Genomic instability occurs in colorectal carcinomas but not in adenomas von Young, Joanne, Leggett, Barbara, Gustafson, Corinne, Ward, Michael, Searle, Jeffrey, Thomas, Lesley, Buttenshaw, Ron, Chenevix-Trench, Georgia

Volltext

A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9 von Young, Joanne, Simms, Lisa A., Tarish, Jabbar, Buttenshaw, Ron, Knight, Ngaire, Anderson, Gregory J., Bell, Andrew, Leggett, Barbara

Volltext

Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region von Leggett, B, Young, J, Buttenshaw, R, Thomas, L, Young, B, Chenevix-Trench, G, Searle, J, Ward, M

Volltext