Opportunities and challenges in the discovery of novel agents for the treatment of malaria von Burrows, Jeremy

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Assessing risks of Plasmodium falciparum resistance to select next-generation antimalarials von Duffey, Maëlle, Blasco, Benjamin, Burrows, Jeremy N., Wells, Timothy N.C., Fidock, David A., Leroy, Didier

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Actives from MMV Open Access Boxes? A suggested way forward von Samby, Kirandeep, Willis, Paul A., Burrows, Jeremy N., Laleu, Benoit, Webborn, Peter J. H.

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P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action von Sanz, Laura M, Crespo, Benigno, De-Cózar, Cristina, Ding, Xavier C, Llergo, Jose L, Burrows, Jeremy N, García-Bustos, Jose F, Gamo, Francisco-Javier

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Targeting Plasmepsins-An Achilles' Heel of the Malaria Parasite von Burrows, Jeremy N., Soldati-Favre, Dominique

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Combating antimicrobial resistance in malaria, HIV and tuberculosis von Duffey, Maëlle, Shafer, Robert W., Timm, Juliano, Burrows, Jeremy N., Fotouhi, Nader, Cockett, Mark, Leroy, Didier

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Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma von Lim, Wilson, Nyuykonge, Bertrand, Eadie, Kimberly, Konings, Mickey, Smeets, Juli, Fahal, Ahmed, Bonifaz, Alexandro, Todd, Matthew, Perry, Benjamin, Samby, Kirandeep, Burrows, Jeremy, Verbon, Annelies, van de Sande, Wendy

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Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis von Doggett, J. Stone, Nilsen, Aaron, Forquer, Isaac, Wegmann, Keith W, Jones-Brando, Lorraine, Yolken, Robert H, Bordón, Claudia, Charman, Susan A, Katneni, Kasiram, Schultz, Tracey, Burrows, Jeremy N, Hinrichs, David J, Meunier, Brigitte, Carruthers, Vern B, Riscoe, Michael K

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Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum von Pires, Camilla Valente, Cassandra, Debora, Xu, Shulin, Laleu, Benoit, Burrows, Jeremy N, Adams, John H

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Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome von Xie, Stanley C, Gillett, David L, Spillman, Natalie J, Tsu, Christopher, Luth, Madeline R, Ottilie, Sabine, Duffy, Sandra, Gould, Alexandra E, Hales, Paul, Seager, Benjamin A, Charron, Carlie L, Bruzzese, Frank, Yang, Xiaofeng, Zhao, Xiansi, Huang, Shih-Chung, Hutton, Craig A, Burrows, Jeremy N, Winzeler, Elizabeth A, Avery, Vicky M, Dick, Lawrence R, Tilley, Leann

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Author Correction: Antimalarial drug discovery: progress and approaches von Siqueira-Neto, Jair L., Wicht, Kathryn J., Chibale, Kelly, Burrows, Jeremy N., Fidock, David A., Winzeler, Elizabeth A.

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Discovery, Synthesis, and Optimization of Antimalarial 4(1H)‑Quinolone-3-Diarylethers von Nilsen, Aaron, Miley, Galen P, Forquer, Isaac P, Mather, Michael W, Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M, Stickles, Allison M, Ryan, Eileen, Kelly, Jane Xu, Doggett, J. Stone, White, Karen L, Hinrichs, David J, Winter, Rolf W, Charman, Susan A, Zakharov, Lev N, Bathurst, Ian, Burrows, Jeremy N, Vaidya, Akhil B, Riscoe, Michael K

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Antimalarial drug discovery – the path towards eradication von BURROWS, JEREMY N, BURLOT, EMILIE, CAMPO, BRICE, CHERBUIN, STEPHANIE, JEANNERET, SARAH, LEROY, DIDIER, SPANGENBERG, THOMAS, WATERSON, DAVID, WELLS, TIMOTHY NC, WILLIS, PAUL

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Evaluation of Current and Emerging Antimalarial Medicines for Inhibition of Toxoplasma gondii Growth in Vitro von Radke, Joshua B, Burrows, Jeremy N, Goldberg, Daniel E, Sibley, L. David

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Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)‑Quinolones with Potent Antimalarial Activity: Structure–Activity and Structure–Property Relationship Studie... von Neelarapu, Raghupathi, Maignan, Jordany R, Lichorowic, Cynthia L, Monastyrskyi, Andrii, Mutka, Tina S, LaCrue, Alexis N, Blake, Lynn D, Casandra, Debora, Mashkouri, Sherwin, Burrows, Jeremy N, Willis, Paul A, Kyle, Dennis E, Manetsch, Roman

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The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Plasmodium falciparum Viability after Antimalarial Treatment In Vitro von Walz, Annabelle, Duffey, Maëlle, Aljayyoussi, Ghaith, Sax, Sibylle, Leroy, Didier, Besson, Dominique, Burrows, Jeremy N, Cherkaoui-Rbati, Mohammed H, Gobeau, Nathalie, Westwood, Marie-Anne, Siethoff, Christoph, Gamo, Francisco-Javier, Mäser, Pascal, Wittlin, Sergio

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Development and application of a PBPK modeling strategy to support antimalarial drug development von Abla, Nada, Howgate, Eleanor, Rowland‐Yeo, Karen, Dickins, Maurice, Bergagnini‐Kolev, Mackenzie C., Chen, Kuan‐Fu, McFeely, Savannah, Bonner, Jennifer J., Santos, Laura G. A., Gobeau, Nathalie, Burt, Howard, Barter, Zoe, Jones, Hannah M., Wesche, David, Charman, Susan A., Möhrle, Jörg J., Burrows, Jeremy N., Almond, Lisa M.

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Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 von Lowe, Martin A., Cardenas, Alvaro, Valentin, Jean-Pierre, Zhu, Zhaoning, Abendroth, Jan, Castro, Jose L., Class, Reiner, Delaunois, Annie, Fleurance, Renaud, Gerets, Helga, Gryshkova, Vitalina, King, Lloyd, Lorimer, Donald D., MacCoss, Malcolm, Rowley, Julian H., Rosseels, Marie-Luce, Royer, Leandro, Taylor, Richard D., Wong, Melanie, Zaccheo, Oliver, Chavan, Vishal P., Ghule, Gokul A., Tapkir, Bapusaheb K., Burrows, Jeremy N., Duffey, Maëlle, Rottmann, Matthias, Wittlin, Sergio, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Striepen, Josefine, Fairhurst, Kate J., Yeo, Tomas, Fidock, David A., Cowman, Alan F., Favuzza, Paola, Crespo-Fernandez, Benigno, Gamo, Francisco Javier, Goldberg, Daniel E., Soldati-Favre, Dominique, Laleu, Benoît, de Haro, Teresa

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Discovery of 1,3,4-oxadiazoles with slow-action activity against Plasmodium falciparum malaria parasites von Andrews, Katherine T., Fisher, Gillian M., Firmin, Meaghan, Liepa, Andris J., Wilson, Tony, Gardiner, James, Mohri, Yacine, Debele, Emmanuel, Rai, Anjana, Davey, Andrew K., Masurier, Antoine, Delion, Alix, Mouratidis, Alexandros A., Hutt, Oliver E., Forsyth, Craig M., Burrows, Jeremy N., Ryan, John H., Riches, Andrew G., Skinner-Adams, Tina S.

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Subtle changes in endochin-like quinolone structure alter the site of inhibition within the cytochrome bc1 complex of Plasmodium falciparum von Stickles, Allison M, de Almeida, Mariana Justino, Morrisey, Joanne M, Sheridan, Kayla A, Forquer, Isaac P, Nilsen, Aaron, Winter, Rolf W, Burrows, Jeremy N, Fidock, David A, Vaidya, Akhil B, Riscoe, Michael K

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