Reprogramming Adult Schwann Cells to Stem Cell-like Cells by Leprosy Bacilli Promotes Dissemination of Infection von Masaki, Toshihiro, Qu, Jinrong, Cholewa-Waclaw, Justyna, Burr, Karen, Raaum, Ryan, Rambukkana, Anura

Volltext

Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis von Mehta, Arpan R., Gregory, Jenna M., Dando, Owen, Carter, Roderick N., Burr, Karen, Nanda, Jyoti, Story, David, McDade, Karina, Smith, Colin, Morton, Nicholas M., Mahad, Don J., Hardingham, Giles E., Chandran, Siddharthan, Selvaraj, Bhuvaneish T.

Volltext

Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology von Zhao, Chen, Devlin, Anna‐Claire, Chouhan, Amit K., Selvaraj, Bhuvaneish T., Stavrou, Maria, Burr, Karen, Brivio, Veronica, He, Xin, Mehta, Arpan R., Story, David, Shaw, Christopher E., Dando, Owen, Hardingham, Giles E., Miles, Gareth B., Chandran, Siddharthan

Volltext

Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy von Serio, Andrea, Bilican, Bilada, Barmada, Sami J., Ando, Dale Michael, Zhao, Chen, Siller, Rick, Burr, Karen, Haghi, Ghazal, Story, David, Nishimura, Agnes Lumi, Carrasco, Monica A., Phatnani, Hemali P., Shum, Carole, Wilmut, Ian, Maniatis, Tom, Shaw, Christopher E., Finkbeiner, Steven, Chandran, Siddharthan

Volltext

A comparison of basal and activity-dependent exon splicing in cortical-patterned neurons of human and mouse origin von Dando, Owen, McQueen, Jamie, Burr, Karen, Kind, Peter C, Chandran, Siddharthan, Hardingham, Giles E, Qiu, Jing

Volltext

Maturation and electrophysiological properties of human pluripotent stem cell‐derived oligodendrocytes von Livesey, Matthew R., Magnani, Dario, Cleary, Elaine M., Vasistha, Navneet A., James, Owain T., Selvaraj, Bhuvaneish T., Burr, Karen, Story, David, Shaw, Christopher E., Kind, Peter C., Hardingham, Giles E., Wyllie, David J.A., Chandran, Siddharthan

Volltext

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction von Perkins, Emma M, Burr, Karen, Banerjee, Poulomi, Mehta, Arpan R, Dando, Owen, Selvaraj, Bhuvaneish T, Suminaite, Daumante, Nanda, Jyoti, Henstridge, Christopher M, Gillingwater, Thomas H, Hardingham, Giles E, Wyllie, David J A, Chandran, Siddharthan, Livesey, Matthew R

Volltext

The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling von Schembs, Leah, Willems, Ariane, Hasenpusch-Theil, Kerstin, Cooper, James D., Whiting, Katie, Burr, Karen, Bøstrand, Sunniva M.K., Selvaraj, Bhuvaneish T., Chandran, Siddharthan, Theil, Thomas

Volltext

Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells von Banerjee, Poulomi, Paza, Evdokia, Perkins, Emma M., James, Owen G., Kenkhuis, Boyd, Lloyd, Amy F., Burr, Karen, Story, David, Yusuf, Dilmurat, He, Xin, Backofen, Rolf, Dando, Owen, Chandran, Siddharthan, Priller, Josef

Volltext

Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells von Bilican, Bilada, Livesey, Matthew R, Haghi, Ghazal, Qiu, Jing, Burr, Karen, Siller, Rick, Hardingham, Giles E, Wyllie, David J A, Chandran, Siddharthan

Volltext

Maturation of AMPAR composition and the GABAAR reversal potential in hPSC-derived cortical neurons von Livesey, Matthew R, Bilican, Bilada, Qiu, Jing, Rzechorzek, Nina M, Haghi, Ghazal, Burr, Karen, Hardingham, Giles E, Chandran, Siddharthan, Wyllie, David J A

Volltext

Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis von Barton, Samantha K, Gregory, Jenna M, Selvaraj, Bhuvaneish T, McDade, Karina, Henstridge, Christopher M, Spires-Jones, Tara L, James, Owen G, Mehta, Arpan R, Story, David, Burr, Karen, Magnani, Dario, Isaacs, Adrian M, Smith, Colin, Chandran, Siddharthan

Volltext

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936 von Toombs, Jamie, Panther, Lindsay, Ornelas, Loren, Liu, Chunyan, Gomez, Emilda, Martín-Ibáñez, Raquel, Cox, Simon R., Ritchie, Stuart J., Harris, Sarah E., Taylor, Adele, Redmond, Paul, Russ, Tom C., Murphy, Lee, Cooper, James D., Burr, Karen, Selvaraj, Bhuvaneish T., Browne, Cathy, Svendsen, Clive N., Cowley, Sally A., Deary, Ian J., Chandran, Siddharthan, Spires-Jones, Tara L., Sareen, Dhruv

Volltext

Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons von Qiu, Jing, McQueen, Jamie, Bilican, Bilada, Dando, Owen, Magnani, Dario, Punovuori, Karolina, Selvaraj, Bhuvaneish T, Livesey, Matthew, Haghi, Ghazal, Heron, Samuel, Burr, Karen, Patani, Rickie, Rajan, Rinku, Sheppard, Olivia, Kind, Peter C, Simpson, T Ian, Tybulewicz, Victor Lj, Wyllie, David Ja, Fisher, Elizabeth Mc, Lowell, Sally, Chandran, Siddharthan, Hardingham, Giles E

Volltext

Hypothermic modulation of human cortical neurons to explore a role for tau protein in neuroprotection von Rzechorzek, Nina M, Dr, Connick, Peter, PhD, Livesey, Matthew R, PhD, Borooah, Shyamanga, MRCP(UK), Patani, Rickie, PhD, Burr, Karen, PhD, Story, David, BSc, Wyllie, David J A, Prof, Hardingham, Giles E, Prof, Chandran, Siddharthan, Prof

Volltext

Radiation-Induced Delayed Bystander-Type Effects Mediated by Hemopoietic Cells von Burr, Karen L., Robinson, Joanne I., Rastogi, Shubhra, Boylan, Michael T., Coates, Philip J., Lorimore, Sally A., Wright, Eric G.

Volltext

Elevated mutation rates in the germline of Polκ mutant male mice von Burr, Karen L-A., Velasco-Miguel, Susana, Duvvuri, Venkata S., McDaniel, Lisa D., Friedberg, Errol C., Dubrova, Yuri E.

Volltext

The effects of MSH2 deficiency on spontaneous and radiation-induced mutation rates in the mouse germline von Burr, KLA, van Duyn-Goedhart, A, Hickenbotham, P, Monger, K, van Buul, PPW, Dubrova, YE

Volltext

The combined effects of xeroderma pigmentosum C deficiency and mutagens on mutation rates in the mouse germ line von MICCOLI, Laurent, BURR, Karen L-A, HICKENBOTHAM, Peter, FRIEDBERG, Errol C, ANGULO, Jaime F, DUBROVA, Yuri E

Volltext

p53 deficiency does not affect mutation rate in the mouse germline von Burr, Karen L-A, Smith, Andrew G, Dubrova, Yuri E

Volltext