Application of a Fluorescence Recovery-Based Polo-Like Kinase 1 Binding Assay to Polo-Like Kinase 2 and Polo-Like Kinase 3 von Tsuji, Kohei, Tamamura, Hirokazu, Burke, Terrence R., Jr

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Recent Advances and New Strategies in Targeting Plk1 for Anticancer Therapy von Lee, Kyung S, Burke, Terrence R, Park, Jung-Eun, Bang, Jeong K, Lee, Eunhye

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Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody–Drug Conjugates von Hwang, Dobeen, Tsuji, Kohei, Park, HaJeung, Burke, Terrence R, Rader, Christoph

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Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1 von Nicklaus, Marc C, Appella, Ettore, Liu, Fa, Lee, Sunhee, Lee, Kyung S, Park, Jung-Eun, Burke Jr, Terrence R, McMahon, James B, Otaka, Akira, Shenoy, Shilpa R, Liao, Chenzhong, Yaffe, Michael B, Soung, Nak-Kyun, Wlodawer, Alexander, Yun, Sang-Moon, Yoon, Do-Young, Lim, Dan, Bang, Jeong K, Moulaei, Tinoush, Kang, Young H, Lim, Yoongho, Lee, Dong-Hee

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Retroviral DNA integration: reaction pathway and critical intermediates von Li, Min, Mizuuchi, Michiyo, Burke Jr, Terrence R, Craigie, Robert

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Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase von Boyer, Paul L, Smith, Steven J, Zhao, Xue Zhi, Das, Kalyan, Gruber, Kevin, Arnold, Eddy, Burke, Jr, Terrence R, Hughes, Stephen H

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A Practical Approach to Bicyclic Carbamoyl Pyridones with Application to the Synthesis of HIV-1 Integrase Strand Transfer Inhibitors von Mahajan, Pankaj S, Smith, Steven J, Hughes, Stephen H, Zhao, Xuezhi, Burke, Jr, Terrence R

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Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inhibitors von Hymel, David, Grant, Robert A., Tsuji, Kohei, Yaffe, Michael B., Burke, Terrence R.

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Affinity enhancement of polo-like kinase 1 polo box domain-binding ligands by a bivalent approach using a covalent kinase-binding component von Tsuji, Kohei, Tamamura, Hirokazu, Burke, Jr, Terrence R

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Structural basis for strand-transfer inhibitor binding to HIV intasomes von Passos, Dario Oliveira, Li, Min, Jozwik, Ilona K., Zhao, Xue Zhi, Santos-Martins, Diogo, Yang, Renbin, Smith, Steven J., Jeon, Youngmin, Forli, Stefano, Hughes, Stephen H., Burke, Terrence R., Craigie, Robert, Lyumkis, Dmitry

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Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macro... von Hymel, David, Tsuji, Kohei, Grant, Robert A, Chingle, Ramesh M, Kunciw, Dominique L, Yaffe, Michael B, Burke, Terrence R

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Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding Inhibitors von Zhao, Xue Zhi, Tsuji, Kohei, Hymel, David, Burke, Jr, Terrence R

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Application of oxime-diversification to optimize ligand interactions within a cryptic pocket of the polo-like kinase 1 polo-box domain von Zhao, Xue Zhi, Hymel, David, Burke, Terrence R.

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Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment... von Lountos, George T, Zhao, Xue Zhi, Kiselev, Evgeny, Tropea, Joseph E, Needle, Danielle, Pommier, Yves, Burke, Terrence R, Waugh, David S

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Folliculin Encoded by the BHD Gene Interacts with a Binding Protein, FNIP1, and AMPK, and Is Involved in AMPK and mTOR Signaling von Baba, Masaya, Hong, Seung-Beom, Sharma, Nirmala, Warren, Michelle B., Nickerson, Michael L., Iwamatsu, Akihiro, Esposito, Dominic, Gillette, William K., Hopkins, Ralph F., Hartley, James L., Furihata, Mutsuo, Oishi, Shinya, Zhen, Wei, Burke, Terrence R., Linehan, W. Marston, Schmidt, Laura S., Zbar, Berton

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Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel von Liu, Fa, Park, Jung-Eun, Qian, Wen-Jian, Lim, Dan, Gräber, Martin, Berg, Thorsten, Yaffe, Michael B, Lee, Kyung S, Burke, Terrence R

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INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay von Smith, Steven J., Ferris, Andrea, Zhao, Xuezhi, Pauly, Gary, Schneider, Joel P., Burke, Terrence R., Hughes, Stephen H.

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Targeted sulfur(VI) fluoride exchange-mediated covalent modification of a tyrosine residue in the catalytic pocket of tyrosyl-DNA phosphodiesterase 1 von Zhao, Xue Zhi, Barakat, Idris A., Lountos, George T., Wang, Wenjie, Agama, Keli, Mahmud, Md Rasel Al, Suazo, Kiall F., Andresson, Thorkell, Pommier, Yves, Burke, Terrence R.

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An NMR strategy for fragment-based ligand screening utilizing a paramagnetic lanthanide probe von Saio, Tomohide, Ogura, Kenji, Shimizu, Kazumi, Yokochi, Masashi, Burke, Terrence R., Inagaki, Fuyuhiko

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Stable and Potent Selenomab-Drug Conjugates von Li, Xiuling, Nelson, Christopher G., Nair, Rajesh R., Hazlehurst, Lori, Moroni, Tina, Martinez-Acedo, Pablo, Nanna, Alex R., Hymel, David, Burke, Terrence R., Rader, Christoph

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