The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins von SHENDEROVA, A, BURKE, T. G, SCHWENDEMAN, S. P

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The Novel Silatecan 7-tert-Butyldimethylsilyl-10-hydroxycamptothecin Displays High Lipophilicity, Improved Human Blood Stability, and Potent Anticancer Activity von Bom, David, Curran, Dennis P, Kruszewski, Stefan, Zimmer, Stephen G, Thompson Strode, J, Kohlhagen, Glenda, Du, Wu, Chavan, Ashok J, Fraley, Kimberly A, Bingcang, Alex L, Latus, Lori J, Pommier, Yves, Burke, Thomas G

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The structural basis of camptothecin interactions with human serum albumin: impact on drug stability von Burke, Thomas G, Mi, Zihou

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The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity von Bom, D., Curran, D.P., Zhang, J., Zimmer, S.G., Bevins, R., Kruszewski, S., Howe, J.N., Bingcang, A., Latus, L.J., Burke, T.G.

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Preferential Binding of the Carboxylate Form of Camptothecin by Human Serum Albumin von Burke, T.G., Mi, Z.H.

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Stabilization of 10-hydroxycamptothecin in poly(lactide-co-glycolide) microsphere delivery vehicles von SHENDEROVA, A, BURKE, T. G, SCHWENDEMAN, S. P

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Novel A,B,E-Ring-Modified Camptothecins Displaying High Lipophilicity and Markedly Improved Human Blood Stabilities von Bom, David, Curran, Dennis P, Chavan, Ashok J, Kruszewski, Stefan, Zimmer, Stephen G, Fraley, Kimberly A, Burke, Thomas G

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Potent topoisomerase I inhibition by novel silatecans eliminates glioma proliferation in vitro and in vivo von POLLACK, I. F, ERFF, M, BOM, D, BURKE, T. G, STRODE, J. T, CURRAN, D. P

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DNA Interactions of Two Clinical Camptothecin Drugs Stabilize Their Active Lactone Forms von Yang, Danzhou, Strode, J. Thompson, Spielmann, H. Peter, Wang, Andrew H.-J, Burke, Thomas G

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Lipid bilayer partitioning and stability of camptothecin drugs von Burke, Thomas G, Mishra, Awadesh K, Wani, Mansukh C, Wall, Monroe E

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Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks von ECKHARDT, S. G, BAKER, S. D, ROTHENBERG, M. L, WHITE, L, WISSEL, P, KUNKA, R, DEPEE, S, LITTLEFIELD, D, BURRIS, H. A, VON HOFF, D. D, ROWINSKY, E. K, ECKARDT, J. R, BURKE, T. G, WARNER, D. L, KUHN, J. G, RODRIGUEZ, G, FIELDS, S, THURMAN, A, SMITH, L

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Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albumin von Burke, Thomas G, Mi, Zihou

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Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the alpha-subunit of the insulin receptor. Identification of a new insulin-binding d... von Kurose, T, Pashmforoush, M, Yoshimasa, Y, Carroll, R, Schwartz, G P, Burke, G T, Katsoyannis, P G, Steiner, D F

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Dissection of the free energy of anthracycline antibiotic binding to DNA: electrostatic contributions von Chaires, J. B, Priebe, W, Graves, D. E, Burke, T. G

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Stabilization of Topotecan in Low pH Liposomes Composed of Distearoylphosphatidylcholine von Burke, Thomas G., Gao, Xiang

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Lack of latex allergen contamination of solutions withdrawn from vials with natural rubber stoppers von Thomsen, DJ, Burke, TG

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A Superactive Insulin: [B 10-aspartic Acid]Insulin(Human) von Schwartz, Gerald P., Burke, G. Thompson, Katsoyannis, Panayotis G.

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Differential Interactions of Camptothecin Lactone and Carboxylate Forms with Human Blood Components von Mi, Zihou, Burke, Thomas G

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Drug allergy assessment at a university hospital and clinic von Pilzer, JD, Burke, TG, Mutnick, AH

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Removal of the basic center from doxorubicin partially overcomes multidrug resistance and decreases cardiotoxicity von Priebe, Waldemar, Van, Nguyen T, Burke, Thomas G, Perez-Soler, Roman

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