Engineered protein nano-compartments for targeted enzyme localization von Choudhary, Swati, Quin, Maureen B, Sanders, Mark A, Johnson, Ethan T, Schmidt-Dannert, Claudia

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Affinity improvement of a therapeutic antibody by structure-based computational design: generation of electrostatic interactions in the transition state stabilizes the antibody-ant... von Kiyoshi, Masato, Caaveiro, Jose M M, Miura, Eri, Nagatoishi, Satoru, Nakakido, Makoto, Soga, Shinji, Shirai, Hiroki, Kawabata, Shigeki, Tsumoto, Kouhei

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Molecular determinants of epidermal growth factor binding: a molecular dynamics study von Sanders, Jeffrey M, Wampole, Matthew E, Thakur, Mathew L, Wickstrom, Eric

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Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling von Peng, Weng Chuan, de Lau, Wim, Madoori, Pramod K, Forneris, Federico, Granneman, Joke C M, Clevers, Hans, Gros, Piet

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Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations von Minde, David P, Radli, Martina, Forneris, Federico, Maurice, Madelon M, Rüdiger, Stefan G D

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Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding von Sirois, Allison R, Deny, Daniela A, Baierl, Samantha R, George, Katia S, Moore, Sarah J

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The preferred substrates for transglutaminase 2 in a complex wheat gluten digest are Peptide fragments harboring celiac disease T-cell epitopes von Dørum, Siri, Arntzen, Magnus Ø, Qiao, Shuo-Wang, Holm, Anders, Koehler, Christian J, Thiede, Bernd, Sollid, Ludvig M, Fleckenstein, Burkhard

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Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants von Maggi, Maristella, Chiarelli, Laurent R, Valentini, Giovanna, Scotti, Claudia

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Four small puzzles that Rosetta doesn't solve von Das, Rhiju

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A major role for side-chain polyglutamine hydrogen bonding in irreversible ataxin-3 aggregation von Natalello, Antonino, Frana, Anna Maria, Relini, Annalisa, Apicella, Alessandra, Invernizzi, Gaetano, Casari, Carlo, Gliozzi, Alessandra, Doglia, Silvia Maria, Tortora, Paolo, Regonesi, Maria Elena

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Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface von Yu, Chung-Ming, Peng, Hung-Pin, Chen, Ing-Chien, Lee, Yu-Ching, Chen, Jun-Bo, Tsai, Keng-Chang, Chen, Ching-Tai, Chang, Jeng-Yih, Yang, Ei-Wen, Hsu, Po-Chiang, Jian, Jhih-Wei, Hsu, Hung-Ju, Chang, Hung-Ju, Hsu, Wen-Lian, Huang, Kai-Fa, Ma, Alex Che, Yang, An-Suei

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Intracellular serine protease inhibitor SERPINB4 inhibits granzyme M-induced cell death von de Koning, Pieter J A, Kummer, J Alain, de Poot, Stefanie A H, Quadir, Razi, Broekhuizen, Roel, McGettrick, Anne F, Higgins, Wayne J, Devreese, Bart, Worrall, D Margaret, Bovenschen, Niels

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Real-time imaging and quantification of amyloid-beta peptide aggregates by novel quantum-dot nanoprobes von Tokuraku, Kiyotaka, Marquardt, Meg, Ikezu, Tsuneya

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Towards engineering hormone-binding globulins as drug delivery agents von Chan, Wee Lee, Zhou, Aiwu, Read, Randy J

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Going beyond clustering in MD trajectory analysis: an application to villin headpiece folding von Rajan, Aruna, Freddolino, Peter L, Schulten, Klaus

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Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes von Isin, Basak, Estiu, Guillermina, Wiest, Olaf, Oltvai, Zoltán N

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Computational design of binding proteins to EGFR domain II von Choi, Yoon Sup, Yoon, Soomin, Kim, Kyung-Lock, Yoo, Jiho, Song, Parkyong, Kim, Minsoo, Shin, Young-Eun, Yang, Won Jun, Noh, Jung-eun, Cho, Hyun-Soo, Kim, Sanguk, Chung, Junho, Ryu, Sung Ho

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Regulatory elements within the prodomain of Falcipain-2, a cysteine protease of the malaria parasite Plasmodium falciparum von Pandey, Kailash C, Barkan, David T, Sali, Andrej, Rosenthal, Philip J

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Molecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor region von Bourne, Yves, Renault, Ludovic, Essono, Sosthène, Mondielli, Grégoire, Lamourette, Patricia, Boquet, Didier, Grassi, Jacques, Marchot, Pascale

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A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family von Lee, Yingying, Mick, Jacob, Furdui, Cristina, Beamer, Lesa J

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