Prediction of designer-recombinases for DNA editing with generative deep learning von Schmitt, Lukas Theo, Paszkowski-Rogacz, Maciej, Jug, Florian, Buchholz, Frank

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The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo von Korotkevich, Ekaterina, Niwayama, Ritsuya, Courtois, Aurélien, Friese, Stefanie, Berger, Nicolas, Buchholz, Frank, Hiiragi, Takashi

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Cre Recombinase and Other Tyrosine Recombinases von Meinke, Gretchen, Bohm, Andrew, Hauber, Joachim, Pisabarro, M. Teresa, Buchholz, Frank

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A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances von Hein, Marco Y., Hubner, Nina C., Poser, Ina, Cox, Jürgen, Nagaraj, Nagarjuna, Toyoda, Yusuke, Gak, Igor A., Weisswange, Ina, Mansfeld, Jörg, Buchholz, Frank, Hyman, Anthony A., Mann, Matthias

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A Tug-of-War between Cell Shape and Polarity Controls Division Orientation to Ensure Robust Patterning in the Mouse Blastocyst von Niwayama, Ritsuya, Moghe, Prachiti, Liu, Yan-Jun, Fabrèges, Dimitri, Buchholz, Frank, Piel, Matthieu, Hiiragi, Takashi

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HIV-1 Proviral DNA Excision Using an Evolved Recombinase von Sarkar, Indrani, Hauber, Ilona, Hauber, Joachim, Buchholz, Frank

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Quantification of evolved DNA-editing enzymes at scale with DEQSeq von Schmitt, Lukas Theo, Schneider, Aksana, Posorski, Jonas, Lansing, Felix, Jelicic, Milica, Jain, Manavi, Sayed, Shady, Buchholz, Frank, Sürün, Duran

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Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1 von Raychaudhuri, Swasti, Loew, Christian, Körner, Roman, Pinkert, Stefan, Theis, Mirko, Hayer-Hartl, Manajit, Buchholz, Frank, Hartl, F. Ulrich

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Efficient Generation and Correction of Mutations in Human iPS Cells Utilizing mRNAs of CRISPR Base Editors and Prime Editors von Sueruen, Duran, Schneider, Aksana, Mircetic, Jovan, Neumann, Katrin, Lansing, Felix, Paszkowski-Rogacz, Maciej, Haenchen, Vanessa, Lee-Kirsch, Min Ae, Buchholz, Frank

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Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators von Scheibe, Marion, Arnoult, Nausica, Kappei, Dennis, Buchholz, Frank, Decottignies, Anabelle, Butter, Falk, Mann, Matthias

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A heterodimer of evolved designer-recombinases precisely excises a human genomic DNA locus von Lansing, Felix, Paszkowski-Rogacz, Maciej, Schmitt, Lukas Theo, Schneider, Paul Martin, Rojo Romanos, Teresa, Sonntag, Jan, Buchholz, Frank

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Antibody-mediated delivery of anti-KRAS-siRNA in vivo overcomes therapy resistance in colon cancer von Bäumer, Sebastian, Bäumer, Nicole, Appel, Neele, Terheyden, Lisa, Fremerey, Julia, Schelhaas, Sonja, Wardelmann, Eva, Buchholz, Frank, Berdel, Wolfgang E, Müller-Tidow, Carsten

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A single reporter mouse line for Vika, Flp, Dre, and Cre-recombination von Karimova, Madina, Baker, Oliver, Camgoz, Aylin, Naumann, Ronald, Buchholz, Frank, Anastassiadis, Konstantinos

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In-cell identification and measurement of RNA-protein interactions von Graindorge, Antoine, Pinheiro, Inês, Nawrocka, Anna, Mallory, Allison C., Tsvetkov, Peter, Gil, Noa, Carolis, Carlo, Buchholz, Frank, Ulitsky, Igor, Heard, Edith, Taipale, Mikko, Shkumatava, Alena

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TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes von Aich, Meghali, Ansari, Asgar Hussain, Ding, Li, Iesmantavicius, Vytautas, Paul, Deepanjan, Choudhary, Chunaram, Maiti, Souvik, Buchholz, Frank, Chakraborty, Debojyoti

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Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins von Hutchins, James R.A, Toyoda, Yusuke, Hegemann, Björn, Poser, Ina, Hériché, Jean-Karim, Sykora, Martina M, Augsburg, Martina, Hudecz, Otto, Buschhorn, Bettina A, Bulkescher, Jutta, Conrad, Christian, Comartin, David, Schleiffer, Alexander, Sarov, Mihail, Pozniakovsky, Andrei, Slabicki, Mikolaj Michal, Schloissnig, Siegfried, Steinmacher, Ines, Leuschner, Marit, Ssykor, Andrea, Lawo, Steffen, Pelletier, Laurence, Stark, Holger, Nasmyth, Kim, Ellenberg, Jan, Durbin, Richard, Buchholz, Frank, Mechtler, Karl, Hyman, Anthony A, Peters, Jan-Michael

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Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding von Toyoda, Yusuke, Cattin, Cedric J., Stewart, Martin P., Poser, Ina, Theis, Mirko, Kurzchalia, Teymuras V., Buchholz, Frank, Hyman, Anthony A., Müller, Daniel J.

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Pairing of single mutations yields obligate Cre-type site-specific recombinases von Hoersten, Jenna, Ruiz-Gómez, Gloria, Lansing, Felix, Rojo-Romanos, Teresa, Schmitt, Lukas Theo, Sonntag, Jan, Pisabarro, M Teresa, Buchholz, Frank

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Nearest-neighbor amino acids of specificity-determining residues influence the activity of engineered Cre-type recombinases von Soni, Anjali, Augsburg, Martina, Buchholz, Frank, Pisabarro, M. Teresa

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Development of a genetic sensor that eliminates p53 deficient cells von Mircetic, Jovan, Dietrich, Antje, Paszkowski-Rogacz, Maciej, Krause, Mechthild, Buchholz, Frank

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