Toll-like receptors 2 and 3 agonists differentially affect oligodendrocyte survival, differentiation, and myelin membrane formation von Bsibsi, Malika, Nomden, Anita, van Noort, Johannes M., Baron, Wia

Volltext

Broad Expression of Toll-Like Receptors in the Human Central Nervous System von BSIBSI, MALIKA, RAVID, RIVKA, GVERIC, DJORDJE, VAN NOORT, JOHANNES M

Volltext

Therapeutic Intervention in Multiple Sclerosis with Alpha B-Crystallin: A Randomized Controlled Phase IIa Trial von van Noort, Johannes M, Bsibsi, Malika, Nacken, Peter J, Verbeek, Richard, Venneker, Edna H G

Volltext

Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators von Bsibsi, Malika, Persoon-Deen, Carla, Verwer, Ronald W.H., Meeuwsen, Sonja, Ravid, Rivka, Van Noort, Johannes M.

Volltext

HspB5 Activates a Neuroprotective Glial Cell Response in Experimental Tauopathy von Hampton, David W., Amor, Sandra, Story, David, Torvell, Megan, Bsibsi, Malika, van Noort, Johannes M., Chandran, Siddarthan

Volltext

Identification of highly connected hub genes in the protective response program of human macrophages and microglia activated by alpha B‐crystallin von Holtman, Inge R., Bsibsi, Malika, Gerritsen, Wouter H., Boddeke, Hendrikus W. G. M., Eggen, Bart J. L., van der Valk, Paul, Kipp, Markus, van Noort, Johannes M., Amor, Sandra

Volltext

The microtubule regulator stathmin is an endogenous protein agonist for TLR3 von Bsibsi, Malika, Bajramovic, Jeffrey J, Vogt, Mario H J, van Duijvenvoorden, Eveline, Baghat, Aabed, Persoon-Deen, Carla, Tielen, Frans, Verbeek, Richard, Huitinga, Inge, Ryffel, Bernhard, Kros, Alexander, Gerritsen, Wouter H, Amor, Sandra, van Noort, Johannes M

Volltext

Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli von Meeuwsen, Sonja, Persoon‐Deen, Carla, Bsibsi, Malika, Ravid, Rivka, Noort, Johannes M. Van

Volltext

Comparison of Human Primary microglia and Human iPSC derived microglia cells as in vitro models for microglia activation von Bsibsi, Malika, Lo, Kimberly, Zanella, Matteo, Geerts, Lieke, Kostense, Stefan, De Groot, Jeroen, Fisher, David F, Vlaming, Marijn

Volltext

TDP‐43 dysregulation and STMN‐2 mis‐splicing upon proteasomal inhibition in potential iPSC‐derived neuronal ALS model von Ritsma, Laila, Bsibsi, Malika, Popalzij, Abeera, Sancerni, Sara Compte, de Kraa, Esther, Magnani, Dario, Turner, Amanda, Oosterveen, Tony, Fisher, David F, Iovino, Mariangela, Vlaming, Marijn

Volltext

Development and characterization of a robust in vitro disease cell line to study tauopathies von Ritsma, Laila, Bsibsi, Malika, Buti, Ludovico, Stevenhagen, Fleur, Sancerni, Sara Compte, de Kraa, Esther, Popalzij, Abeera, Iovino, Mariangela, Oosterveen, Tony, Turner, Amanda, Fisher, David F, Vlaming, Marijn

Volltext

The link between small heat shock proteins and the immune system von van Noort, Johannes M., Bsibsi, Malika, Nacken, Peter, Gerritsen, Wouter H., Amor, Sandra

Volltext

αB-Crystallin Is a Target for Adaptive Immune Responses and a Trigger of Innate Responses in Preactive Multiple Sclerosis Lesions von van Noort, Johannes M, Bsibsi, Malika, Gerritsen, Wouter H, van der Valk, Paul, Bajramovic, Jeffrey J, Steinman, Lawrence, Amor, Sandra

Volltext

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin von Bsibsi, Malika, Peferoen, Laura A. N., Holtman, Inge R., Nacken, Peter J., Gerritsen, Wouter H., Witte, Maarten E., van Horssen, Jack, Eggen, Bart J. L., van der Valk, Paul, Amor, Sandra, van Noort, Johannes M.

Volltext

Pentraxin‐3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease von Ummenthum, Kimberley, Peferoen, Laura A. N., Finardi, Annamaria, Baker, David, Pryce, Gareth, Mantovani, Alberto, Bsibsi, Malika, Bottazzi, Barbara, Peferoen‐Baert, Regina, van der Valk, Paul, Garlanda, Cecilia, Kipp, Markus, Furlan, Roberto, van Noort, Johannes M., Amor, Sandra

Volltext

Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA micropar... von van Noort, Johannes M, Bsibsi, Malika, Nacken, Peter J, Gerritsen, Wouter H, Amor, Sandra, Holtman, Inge R, Boddeke, Erik, van Ark, Ingrid, Leusink-Muis, Thea, Folkerts, Gert, Hennink, Wim E, Amidi, Maryam

Volltext

Alpha-B-Crystallin Induces an Immune-Regulatory and Antiviral Microglial Response in Preactive Multiple Sclerosis Lesions von Bsibsi, Malika, Holtman, Inge R., Gerritsen, Wouter H., Eggen, Bart J. L., Boddeke, Erik, van der Valk, Paul, van Noort, Johannes M., Amor, Sandra

Volltext

Demyelination during multiple sclerosis is associated with combined activation of microglia and macrophages by IFN-gamma and alpha B-crystallin von Bsibsi, Malika, Peferoen, Laura, Holtman, Inge, Nacken, Peter, Gerritsen, Wouter, Witte, Maarten, Van Horssen, Jack, Eggen, Bart, Van Der Valk, Paul, Amor, Sandra, Van Noort, Johannes

Volltext

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-[gamma] and alpha B-crystallin von Bsibsi, Malika, Peferoen, Laura A, N, Holtman, Inge R, Nacken, Peter J, Gerritsen, Wouter H, Witte, Maarten E, van Horssen, Jack, Eggen, Bart J, L, van der Valk, Paul, Amor, Sandra, van Noort, Johannes M

Volltext

Inhibition of microglial inflammation by the MLK inhibitor CEP‐1347 von Lund, Søren, Porzgen, Peter, Mortensen, Anne Louise, Hasseldam, Henrik, Bozyczko‐Coyne, Donna, Morath, Siegfried, Hartung, Thomas, Bianchi, Marina, Ghezzi, Pietro, Bsibsi, Malika, Dijkstra, Sipke, Leist, Marcel

Volltext