377-OR: Stabilizing 14-3-3 and ChREBP Cytoplasmic Interaction to Rescue ß-Cells from Glucolipotoxicity von KATZ, LIORA S., TSE, ISABELLE L., VISSER, EMIRA, BAUMEL-ALTERZON, SHARON, KAISER, MARKUS, BRUNSVELD, LUC M., PENNINGS, MARLOES, OTTMANN, CHRISTIAN, SCOTT, DONALD

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Modulators of 14-3‑3 Protein–Protein Interactions von Stevers, Loes M, Sijbesma, Eline, Botta, Maurizio, MacKintosh, Carol, Obsil, Tomas, Landrieu, Isabelle, Cau, Ylenia, Wilson, Andrew J, Karawajczyk, Anna, Eickhoff, Jan, Davis, Jeremy, Hann, Michael, O’Mahony, Gavin, Doveston, Richard G, Brunsveld, Luc, Ottmann, Christian

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Supramolecular Nanoscaffolds within Cytomimetic Protocells as Signal Localization Hubs von Magdalena Estirado, Eva, Mason, Alexander F, Alemán García, Miguel Ángel, van Hest, Jan C. M, Brunsveld, Luc

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Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR von Stevers, Loes M., Wolter, Madita, Carlile, Graeme W., Macdonald, Dwight, Richard, Luc, Gielkens, Frank, Hanrahan, John W., Thomas, David Y., Chakka, Sai Kumar, Peterson, Mark L., Thomas, Helmut, Brunsveld, Luc, Ottmann, Christian

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A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14‐3‐3 von de Vink, Pim J., Briels, Jeroen M., Schrader, Thomas, Milroy, Lech‐Gustav, Brunsveld, Luc, Ottmann, Christian

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DNA‐Mediated Protein Shuttling between Coacervate‐Based Artificial Cells von Mashima, Tsuyoshi, Stevendaal, Marleen H. M. E., Cornelissens, Femke R. A., Mason, Alexander F., Rosier, Bas J. H. M., Altenburg, Wiggert J., Oohora, Koji, Hirayama, Shota, Hayashi, Takashi, Hest, Jan C. M., Brunsveld, Luc

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Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2 Photocatalysis von Bottecchia, Cecilia, Erdmann, Nico, Tijssen, Patricia M. A., Milroy, Lech-Gustav, Brunsveld, Luc, Hessel, Volker, Noël, Timothy

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Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR von Stevers, Loes M., Lam, Chan V., Leysen, Seppe F. R., Meijer, Femke A., van Scheppingen, Daphne S., de Vries, Rens M. J. M., Carlile, Graeme W., Milroy, Lech G., Thomas, David Y., Brunsveld, Luc, Ottmann, Christian

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A Thermodynamic Model for Multivalency in 14-3‑3 Protein–Protein Interactions von Stevers, Loes M, de Vink, Pim J, Ottmann, Christian, Huskens, Jurriaan, Brunsveld, Luc

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Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering von Wolter, Madita, Valenti, Dario, Cossar, Peter J., Levy, Laura M., Hristeva, Stanimira, Genski, Thorsten, Hoffmann, Torsten, Brunsveld, Luc, Tzalis, Dimitrios, Ottmann, Christian

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Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3‑3 Hub Protein Interactions von Cossar, Peter J, Wolter, Madita, van Dijck, Lars, Valenti, Dario, Levy, Laura M, Ottmann, Christian, Brunsveld, Luc

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Dynamic Protease Activation on a Multimeric Synthetic Protein Scaffold via Adaptable DNA‐Based Recruitment Domains von Mashima, Tsuyoshi, Rosier, Bas J. H. M., Oohora, Koji, Greef, Tom F. A., Hayashi, Takashi, Brunsveld, Luc

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Conjugated Protein Domains as Engineered Scaffold Proteins von Lemmens, Lenne J M, Ottmann, Christian, Brunsveld, Luc

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Bioactivity-guided mapping and navigation of chemical space von Waldmann, Herbert, Renner, Steffen, van Otterlo, Willem A L, Dominguez Seoane, Marta, Möcklinghoff, Sabine, Hofmann, Bettina, Wetzel, Stefan, Schuffenhauer, Ansgar, Ertl, Peter, Oprea, Tudor I, Steinhilber, Dieter, Brunsveld, Luc, Rauh, Daniel

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Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin von Taha, Mohamed S, Nouri, Kazem, Milroy, Lech G, Moll, Jens M, Herrmann, Christian, Brunsveld, Luc, Piekorz, Roland P, Ahmadian, Mohammad R

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An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3‑3 Interaction with NF-κBUtilizing a Reversible Covalent Tethering Approach von Wolter, Madita, Valenti, Dario, Cossar, Peter J, Hristeva, Stanimira, Levy, Laura M, Genski, Thorsten, Hoffmann, Torsten, Brunsveld, Luc, Tzalis, Dimitrios, Ottmann, Christian

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Designed Asymmetric Protein Assembly on a Symmetric Scaffold von Lemmens, Lenne J. M., Roodhuizen, Job A. L., Greef, Tom F. A., Markvoort, Albert J., Brunsveld, Luc

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Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome von Rosier, Bas J. H. M., Markvoort, Albert J., Gumí Audenis, Berta, Roodhuizen, Job A. L., den Hamer, Anniek, Brunsveld, Luc, de Greef, Tom F. A.

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Dynamic modulation of proximity-induced enzyme activity using supramolecular polymers von Magdalena Estirado, Eva, Rosier, Bas J. H. M, de Greef, Tom F. A, Brunsveld, Luc

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From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking von Visser, Emira J., Jaishankar, Priyadarshini, Sijbesma, Eline, Pennings, Marloes A. M., Vandenboorn, Edmee M. F., Guillory, Xavier, Neitz, R. Jeffrey, Morrow, John, Dutta, Shubhankar, Renslo, Adam R., Brunsveld, Luc, Arkin, Michelle R., Ottmann, Christian

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