Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disorders von Bruns, Robert F., Mitchell, Stephen N., Wafford, Keith A., Harper, Alex J., Shanks, Elaine A., Carter, Guy, O'Neill, Michael J., Murray, Tracey K., Eastwood, Brian J., Schaus, John M., Beck, James P., Hao, Junliang, Witkin, Jeffrey M., Li, Xia, Chernet, Eyassu, Katner, Jason S., Wang, Hong, Ryder, John W., Masquelin, Meghane E., Thompson, Linda K., Love, Patrick L., Maren, Deanna L., Falcone, Julie F., Menezes, Michelle M., Zhang, Linli, Yang, Charles R., Svensson, Kjell A.

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Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior von Ferris, Craig F., Lu, Shi-fang, Messenger, Tara, Guillon, Christophe D., Heindel, Ned, Miller, Marvin, Koppel, Gary, Robert Bruns, F., Simon, Neal G.

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Rules for Identifying Potentially Reactive or Promiscuous Compounds von Bruns, Robert F, Watson, Ian A

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Mutual Cooperativity of Three Allosteric Sites on the Dopamine D1 Receptor von Wang, Xushan, Hembre, Erik J., Goldsmith, Paul J., Beck, James P., Svensson, Kjell A., Willard, Francis S., Bruns, Robert F.

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Effects of DPTQ, a novel positive allosteric modulator of the dopamine D1 receptor, on spontaneous eye blink rate and spatial working memory in the nonhuman primate von Castner, Stacy A., Zhang, Linli, Yang, Charles R., Hao, Junliang, Cramer, Jeffrey W., Wang, Xushan, Bruns, Robert F., Marston, Hugh, Svensson, Kjell A., Williams, Graham V.

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Intracellular Binding Site for a Positive Allosteric Modulator of the Dopamine D1 Receptor von Wang, Xushan, Heinz, Beverly A., Qian, Yue-Wei, Carter, Joan H., Gadski, Robert A., Beavers, Lisa S., Little, Sheila P., Yang, Charles R., Beck, James P., Hao, Junliang, Schaus, John M., Svensson, Kjell A., Bruns, Robert F.

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Synthesis and Pharmacological Characterization of 2‑(2,6-Dichlorophenyl)-1-((1S,3R)‑5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)‑yl)ethan-1-o... von Hao, Junliang, Beck, James P, Schaus, John M, Krushinski, Joseph H, Chen, Qi, Beadle, Christopher D, Vidal, Paloma, Reinhard, Matthew R, Dressman, Bruce A, Massey, Steven M, Boulet, Serge L, Cohen, Michael P, Watson, Brian M, Tupper, David, Gardinier, Kevin M, Myers, Jason, Johansson, Anette M, Richardson, Jeffery, Richards, Daniel S, Hembre, Erik J, Remick, David M, Coates, David A, Bhardwaj, Rajni M, Diseroad, Benjamin A, Bender, David, Stephenson, Greg, Wolfangel, Craig D, Diaz, Nuria, Getman, Brian G, Wang, Xu-shan, Heinz, Beverly A, Cramer, Jeff W, Zhou, Xin, Maren, Deanna L, Falcone, Julie F, Wright, Rebecca A, Mitchell, Stephen N, Carter, Guy, Yang, Charles R, Bruns, Robert F, Svensson, Kjell A

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An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis von Svensson, Kjell A, Heinz, Beverly A, Schaus, John M, Beck, James P, Hao, Junliang, Krushinski, Joseph H, Reinhard, Matthew R, Cohen, Michael P, Hellman, Sarah L, Getman, Brian G, Wang, Xushan, Menezes, Michelle M, Maren, Deanna L, Falcone, Julie F, Anderson, Wesley H, Wright, Rebecca A, Morin, S Michelle, Knopp, Kelly L, Adams, Benjamin L, Rogovoy, Borys, Okun, Ilya, Suter, Todd M, Statnick, Michael A, Gehlert, Donald R, Nelson, David L, Lucaites, Virginia L, Emkey, Renee, DeLapp, Neil W, Wiernicki, Todd R, Cramer, Jeffrey W, Yang, Charles R, Bruns, Robert F

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Potent and Selective 1,2,3-Trisubstituted Indole NPY Y-1 Antagonists von Hipskind, Philip A, Lobb, Karen L, Nixon, James A, Britton, Thomas C, Bruns, Robert F, Catlow, John, Dieckman-McGinty, Donna K, Gackenheimer, Susan L, Gitter, Bruce D, Iyengar, Smriti, Schober, Douglas A, Simmons, Rosa M. A, Swanson, Steve, Zarrinmayeh, Hamideh, Zimmerman, Dennis M, Gehlert, Donald R

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Azetidinones as vasopressin V1a antagonists von Guillon, Christophe D., Koppel, Gary A., Brownstein, Michael J., Chaney, Michael O., Ferris, Craig F., Lu, Shi-fang, Fabio, Karine M., Miller, Marvin J., Heindel, Ned D., Hunden, David C., Cooper, Robin D.G., Kaldor, Stephen W., Skelton, Jeffrey J., Dressman, Bruce A., Clay, Michael P., Steinberg, Mitchell I., Bruns, Robert F., Simon, Neal G.

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Synthesis and Evaluation of a Series of Novel 2-[(4-Chlorophenoxy)methyl]- benzimidazoles as Selective Neuropeptide Y Y1 Receptor Antagonists von Zarrinmayeh, Hamideh, Nunes, Anne M, Ornstein, Paul L, Zimmerman, Dennis M, Arnold, M. Brian, Schober, Douglas A, Gackenheimer, Susan L, Bruns, Robert F, Hipskind, Philip A, Britton, Thomas C, Cantrell, Buddy E, Gehlert, Donald R

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Inhibition of protein kinase C by calphostin C is light-dependent von Bruns, Robert F., Miller, F.Dean, Merriman, Ronald L., Howbert, J.Jeffry, Heath, William F., Kobayashi, Eiji, Takahashi, Isami, Tamaoki, Tatsuya, Nakano, Hirofumi

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PD 81,723, an allosteric enhancer of the A1 adenosine receptor, lowers the threshold for ischemic preconditioning in dogs von MIZUMURA, T, AUCHAMPACH, J. A, LINDEN, J, BRUNS, R. F, GROSS, G. J

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The neuropeptide Y Y1 antagonist, 1229U91, a potent agonist for the human pancreatic polypeptide-preferring (NPY Y4) receptor von Schober, D A, Van Abbema, A M, Smiley, D L, Bruns, R F, Gehlert, D R

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A rapid filtration assay for soluble receptors using polyethylenimine-treated filters von Bruns, Robert F., Lawson-Wendling, Karen, Pugsley, Thomas A.

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In Vitro Characterization of a Novel Allosteric Potentiator of the Dopamine D1 Receptor von Heinz, Beverly A, Schaus, John M, Beck, James P, Hao, Junliang, Wang, Xushan, Krushinski, Joseph, Reinhard, Matthew, Hellman, Sarah, Getman, Brian, Suter, Todd, Nelson, David, Wiernicki, Todd, Cohen, Michael P, Yang, Charles R, Svensson, Kjell A, Bruns, Robert F

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3-Aryl-1,2-diacetamidopropane Derivatives as Novel and Potent NK-1 Receptor Antagonists von Hipskind, Philip A, Howbert, J. Jeffry, Bruns, Robert F, Cho, Steven S. Y, Crowell, Thomas A, Foreman, Mark M, Gehlert, Donald R, Iyengar, Smriti, Johnson, Kirk W, Krushinski, Joseph H, Li, Dominic L, Lobb, Karen L, Mason, Norman R, Muehl, Brian S, Nixon, James A, Phebus, Lee A, Regoli, Domenico, Simmons, Rosa M, Threlkeld, Penny G, Waters, Diane C, Gitter, Bruce D

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Behavioral Effects of a Novel Allosteric Potentiator of the Dopamine D1 Receptor in Human D1 Knock‐in Mice and Rhesus Monkeys von Svensson, Kjell A, Beck, James P, Hao, Junliang, Schaus, John M, Maren, Deanna L, Menezes, Michelle M, Falcone, Julie F, Anderson, Wesley, Knopp, Kelly, Adams, Benjamin L, Witkin, Jeffrey M, Li, Xia, Cramer, Jeffrey, Harper, Alex J, Wafford, Keith A, Zhang, Linli, Yang, Charles R, Bruns, Robert F

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Neurochemical Profile of a Novel Allosteric Potentiator of the Dopamine D1 Receptor von Falcone, Julie F, Mitchell, Stephen N, Carter, Guy, Maren, Deanna L, Katner, Jason, Chernet, Eyassu, Wright, Rebecca A, Wang, Hong, Ryder, John W, Morin, Michelle, Gehlert, Donald R, Johnson, Michael P, Beck, James P, Hao, Junliang, Menezes, Michelle M, Bruns, Robert F, Svensson, Kjell A

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Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes von BRUNS, R. F, FERGUS, J. H, BADGER, E. W, BRISTOL, J. A, SANTAY, L. A, HARTMAN, J. D, HAYS, S. J, HUANG, C. C

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