The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes von Frkic, Rebecca L., Richter, Katharina, Bruning, John B.

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Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism von Kroker, Alice J., Bruning, John B.

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A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis von Mohamed, Hebatalla, Child, Stella A., Bruning, John B., Bell, Stephen G.

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Structural mechanism for signal transduction in RXR nuclear receptor heterodimers von Kojetin, Douglas J., Matta-Camacho, Edna, Hughes, Travis S., Srinivasan, Sathish, Nwachukwu, Jerome C., Cavett, Valerie, Nowak, Jason, Chalmers, Michael J., Marciano, David P., Kamenecka, Theodore M., Shulman, Andrew I., Rance, Mark, Griffin, Patrick R., Bruning, John B., Nettles, Kendall W.

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Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-δ p66 Subunit and Flap Endonuclease-1 von Bruning, John B., Shamoo, Yousif

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Expressing a moth abcc2 gene in transgenic Drosophila causes susceptibility to Bt Cry1Ac without requiring a cadherin-like protein receptor von Stevens, Tristan, Song, Sisi, Bruning, John B., Choo, Amanda, Baxter, Simon W.

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DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex von Zhang, Jun, Chalmers, Michael J, Stayrook, Keith R, Burris, Lorri L, Wang, Yongjun, Busby, Scott A, Pascal, Bruce D, Garcia-Ordonez, Ruben D, Bruning, John B, Istrate, Monica A, Kojetin, Douglas J, Dodge, Jeffrey A, Burris, Thomas P, Griffin, Patrick R

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Structure of the Mycobacterium tuberculosis d-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine von BRUNING, John B, MURILLO, Ana C, CHACON, Ofelia, BARLETTA, Raúl G, SACCHETTINI, James C

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An improved methodology to evaluate crop salt tolerance from field trials von van Straten, G., de Vos, A.C., Rozema, J., Bruning, B., van Bodegom, P.M.

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Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features von Bonnefond, Amélie, Raimondo, Anne, Stutzmann, Fanny, Ghoussaini, Maya, Ramachandrappa, Shwetha, Bersten, David C, Durand, Emmanuelle, Vatin, Vincent, Balkau, Beverley, Lantieri, Olivier, Raverdy, Violeta, Pattou, François, Van Hul, Wim, Van Gaal, Luc, Peet, Daniel J, Weill, Jacques, Miller, Jennifer L, Horber, Fritz, Goldstone, Anthony P, Driscoll, Daniel J, Bruning, John B, Meyre, David, Whitelaw, Murray L, Froguel, Philippe

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HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions von Zheng, Jie, Chang, Mi Ra, Stites, Ryan E., Wang, Yong, Bruning, John B., Pascal, Bruce D., Novick, Scott J., Garcia-Ordonez, Ruben D., Stayrook, Keith R., Chalmers, Michael J., Dodge, Jeffrey A., Griffin, Patrick R.

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Coupling of receptor conformation and ligand orientation determine graded activity von Nettles, Kendall W, Bruning, John B, Parent, Alexander A, Gil, German, Zhao, Min, Nowak, Jason, Pace, Margaret C, Smith, Carolyn L, Afonine, Pavel V, Adams, Paul D, Katzenellenbogen, John A

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Targeting Unconventional Pathways in Pursuit of Novel Antifungals von Nguyen, Stephanie, Truong, Jia Q, Bruning, John B

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Biochemical and in silico characterization of glycosyltransferases from red sweet cherry (Prunus avium L.) reveals their broad specificity toward phenolic substrates von Clayton-Cuch, Daniel, Yu, Long, McDougal, Daniel, Burbidge, Crista A., Bruning, John B., Bradley, David, Böttcher, Christine, Bulone, Vincent

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Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes von Thompson, Andrew P, Salaemae, Wanisa, Pederick, Jordan L, Abell, Andrew D, Booker, Grant W, Bruning, John B, Wegener, Kate L, Polyak, Steven W

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PPARγ in Complex with an Antagonist and Inverse Agonist: a Tumble and Trap Mechanism of the Activation Helix von Frkic, Rebecca L., Marshall, Andrew C., Blayo, Anne-Laure, Pukala, Tara L., Kamenecka, Theodore M., Griffin, Patrick R., Bruning, John B.

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Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function von Bersten, David C, Bruning, John B, Peet, Daniel J, Whitelaw, Murray L

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Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia von Downes, Charlotte E. J., McClure, Barbara J., Bruning, John B., Page, Elyse, Breen, James, Rehn, Jacqueline, Yeung, David T., White, Deborah L.

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JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies von Downes, Charlotte EJ, McClure, Barbara J., McDougal, Daniel P., Heatley, Susan L., Bruning, John B., Thomas, Daniel, Yeung, David T., White, Deborah L.

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Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus von Vandborg, Bethiney C., Horsfall, Aimee J., Pederick, Jordan L., Abell, Andrew D., Bruning, John B.

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